Ukuthelekisa ipropylene glycol kunye ne-carboxymethylcellulose (CMC) idinga ukuqonda iipropati zabo, izicelo, iinzuzo, kunye neengxaki. Zombini iikhompawundi zisetyenziswa kakhulu kumashishini ahlukeneyo, kubandakanya amayeza, ukutya, izinto zokuthambisa, kunye nokhathalelo lomntu.
Intshayelelo:
Ipropylene glycol (PG) kunye ne-carboxymethylcellulose (CMC) ziikhompawundi eziguquguqukayo ezisetyenziswa kumashishini ahlukeneyo ngenxa yeempawu zazo ezizodwa. I-PG yikhompawundi yendalo eyenziweyo enezicelo ezixhaphakileyo njengesinyibilikisi, i-humectant, kunye nesipholisi. I-CMC, kwelinye icala, iphuma kwiselulosi eyaziwa ngokujiya, ukuzinzisa, kunye neempawu zayo zokumisela. Zombini iikhompawundi zidlala indima ebalulekileyo kwiimveliso ezahlukeneyo, kubandakanya amayeza, ukutya, izinto zokuthambisa, kunye nezinto zokhathalelo lomntu.
Ulwakhiwo lweMichiza:
Ipropylene Glycol (PG):
Ifomula yeMichiza: C₃H₈O₂
Ulwakhiwo: I-PG yinto encinci, ayinambala, ayinavumba, kwaye incasa ephilayo ikhompawundi enamaqela amabini e-hydroxyl. Kukwiklasi yee-diols (i-glycols) kwaye ixutywe ngamanzi, utywala, kunye nezinyibilikisi ezininzi zezinto eziphilayo.
I-Carboxymethylcellulose (CMC):
Ifomula yeMichiza: [C₆H₉O₄(OH)₃-x(OCH₂COOH)x]n
Ubume: I-CMC ithathwe kwi-cellulose ngokutshintshwa kwamaqela e-hydroxyl kunye namaqela e-carboxymethyl. Yenza i-polymer e-soluble yamanzi kunye namazinga ahlukeneyo okutshintshwa, okuchaphazela iimpawu zayo ezifana ne-viscosity kunye ne-solubility.
Usetyenziso:
Ipropylene Glycol (PG):
Ishishini lokutya kunye nesiselo: I-PG iqhele ukusetyenziswa njenge-humectant, i-solvent, kunye ne-preservative ekutyeni nakwimveliso yesiselo.
I-Pharmaceuticals: Isebenza njengesinyibilikisi kwimixube yonyango yomlomo, etofwayo, kunye neyezihloko.
Izithambiso kunye noNonophelo loBuqu: I-PG ikhona kwiimveliso ezahlukeneyo ezifana neloshini, iishampu, kunye nezithambiso ngenxa yeempawu zayo zokufuma.
I-Carboxymethylcellulose (CMC):
Ishishini lokutya: I-CMC isebenza njengento etyebisayo, isizinzisi, kunye nokugcina ukufuma kwiimveliso zokutya ezifana ne-ayisikhrimu, iisosi, kunye nokunxiba.
Amachiza: I-CMC isetyenziswa njengesibophelelo kunye ne-disintegrant kwi-tablet formulations kunye ne-excipient kwizisombululo ze-ophthalmic.
IiMveliso zoNonophelo lomntu: Ifumaneka kwintlama yamazinyo, iikhrimu, kunye neloshini ngenxa yokuqina kwayo kunye neziphumo zokuzinzisa.
Iinkcazelo ngeempawu:
Ipropylene Glycol (PG):
IHygroscopic: I-PG ifunxa amanzi, iwenza abe luncedo njenge-humectant kwizicelo ezahlukeneyo.
Ubuthi obuphantsi: Ibonwa ngokubanzi njengekhuselekile (GRAS) ngabasemagunyeni abalawulayo xa isetyenziswa kwiindawo ezithile ezichaziweyo.
I-Viscosity ephantsi: I-PG ine-viscosity ephantsi, enokuba luncedo kwizicelo ezifuna ukumanzi.
I-Carboxymethylcellulose (CMC):
I-Arhente eQinisayo: I-CMC yenza izisombululo ze-viscous, iyenza isebenze njenge-thickener kunye ne-stabilizer ekutyeni nakwiimveliso zokhathalelo lomntu.
Ukunyibilika kwamanzi: I-CMC inyibilika ngokulula emanzini, ivumela ukudityaniswa lula kwimixube.
Iipropathi zokubumba ifilimu: I-CMC inokwenza iifilimu ezicacileyo, eziluncedo kwizicelo ezahlukeneyo ezifana nezaleko kunye nezinto ezincamathelayo.
Ukhuseleko:
Ipropylene Glycol (PG):
Ngokubanzi ibonwa njengeKhuselekileyo (GRAS): I-PG inembali ende yokusetyenziswa ngokukhuselekileyo ekutyeni, kumayeza, nakwiimveliso zokhathalelo lomntu.
Ubuthi obuphantsi: Ukutya okuninzi kunokubangela ukungonwabi kwesisu, kodwa ubuthi obukhulu bunqabile.
I-Carboxymethylcellulose (CMC):
Ngokubanzi ithathwa njengeKhuselekileyo (GRAS): I-CMC ithathwa njengekhuselekile ukuba ingasetyenziswa kunye nokusetyenziswa kwezihloko.
Ukufunxa okuncinci: I-CMC ayifakwanga kakuhle kumzila wesisu, inciphisa ukuvezwa kwenkqubo kunye nobutyhefu obunokubakho.
Impembelelo yokusingqongileyo:
Ipropylene Glycol (PG):
I-Biodegradability: I-PG iyakwazi ukubola phantsi kweemeko ze-aerobic, inciphisa impembelelo yayo yokusingqongileyo.
Imithombo eHlaziywayo: Abanye abavelisi bavelisa i-PG kwimithombo ehlaziyekayo efana nombona okanye umoba.
I-Carboxymethylcellulose (CMC):
I-Biodegradable: I-CMC ithathwe kwi-cellulose, isibonelelo esinokuhlaziywa kunye ne-biodegradable, isenza ukuba sivumelane nokusingqongileyo.
Ayinatyhefu: I-CMC ayibeki mngcipheko ubalulekileyo kwizinto eziphilayo zasemanzini okanye ezisemhlabeni.
Izinto eziluncedo kunye nezingeloncedo:
Ipropylene Glycol (PG):
Izinto eziluncedo:
I-solvent ehlukeneyo kunye ne-humectant.
Ubuthi obuphantsi kunye nesimo se-GRAS.
Ixutywe namanzi kunye nezinyibilikisi ezininzi eziphilayo.
Izinto ezingeloncedo:
Ubunakho bokuqina obuncinci.
Ukubanakho ukucaphuka kwesikhumba kubantu ababuthathaka.
Isesichengeni sokuthotywa phantsi kweemeko ezithile.
I-Carboxymethylcellulose (CMC):
Izinto eziluncedo:
Iipropati ezigqwesileyo zokujiya kunye nokuzinzisa.
I-Biodegradable kwaye ihambelana nokusingqongileyo.
Uluhlu olubanzi lwezicelo ekutyeni, kumayeza, nakukhathalelo lomntu.
Izinto ezingeloncedo:
Ukunyibilika okulinganiselweyo kwizinyibilikisi eziphilayo.
I-viscosity ephezulu kwiindawo eziphantsi.
Isenokufuna amanqanaba aphezulu osetyenziso xa kuthelekiswa nezinye izityebi.
ipropylene glycol (PG) kunye ne-carboxymethylcellulose (CMC) zikhompawundi ezixabisekileyo ezineempawu ezicacileyo kunye nokusetyenziswa. I-PG igqwesile njengesinyibilikisi kunye ne-humectant, ngelixa i-CMC ikhazimla njengento ejiyileyo kunye nezinzisi. Zombini iikhompawundi zibonelela ngezinto eziluncedo kwimimandla yazo, kunye ne-PG exatyisiweyo ngenxa yetyhefu ephantsi kunye nokungahambi kakuhle, kunye ne-CMC exatyiswe ngokuguquguquka kwayo kunye nobuchule bayo bokutyeba. Ukukhetha phakathi kwe-PG kunye ne-CMC kuxhomekeke kwiimfuno ezithile zoqulunqo, iingqwalasela zolawulo, kunye neenkxalabo zokusingqongileyo. Ekugqibeleni, zombini iikhompawundi zinegalelo elikhulu kuluhlu olwahlukeneyo lweemveliso ezikhoyo kwimarike namhlanje.
Ixesha lokuposa: Mar-20-2024