Hydroxypropyl methylcelculose (hpmc)Ngaba i-Polynential Polynent Polymer ye-Polymer esetyenziswe ngokubanzi isetyenziswa kwicandelo lolwakhiwo, amayeza, i-cosmetics, ishishini lokutya kunye nepetroleum. Isekwe kwiselfowuni yendalo kwaye ifunyenwe ngokulandelelana kweekhemikhali. Inamanzi amnandi, i-tickeng, ukwenza ifilimu kunye nepropathi yomthendeleko. Ukuveliswa kwemveliso ye-kimbacell®hpmc ikakhulu kubandakanya ikakhulu indlela yokuguqula i-Selelose. Ukuphendula ngokuguquguqukayo kubandakanya ubuchwephesha kunye ne-hydroxyypropy.
I-1. Izinto ezingafunekiyo kunye nokwamkelwa kwe-HPMC
I-Selew Selelose iZixhobo eziShumi: Ukuveliswa kwe-HPMC kuqala nge-seluplose yendalo. Imithombo yolwazi eqhelekileyo ibandakanya imicu yokutyala njenge-pulp, umqhaphu, kunye ne-hemp. Ukuqinisekisa inkqubela phambili egudileyo yokuphendula ngokulandelayo, i-seluplose ihlala iqatha ukuba isuswe ukususwa kunye nokunyusa umsebenzi wokuphendula.
Amanyathelo okhuseleko: Ukuthathwa kweSeluplose kubandakanya amanyathelo anjengokuhlamba, ukomisa, kwaye ukutyhobe ukuze aqhubekeke kwi-selsulose kwi-Granulase okanye kwiFowded Foections.
2. Inkqubo ye-Synthesis ye-HPMC
Inkqubo ye-Synthesis ye-HPMC ikakhulu ibandakanya i-methyling kunye ne-hydroxypropyproption, eqhutywa phantsi kweemeko zeAlkaline. Inkqubo ethile yemveliso ibandakanya la manyathelo alandelayo:
Ukusebenza kweselselose: Ukuze wenze lula i-selsulose ukusabela ngokukhawuleza, kuyimfuneko ukunyanga isellulose ngesisombululo se-alkaline enjenge-sodium hydroxide (i-nah) i-sloullese ye-slollese. Okweli nqanaba, i-crystallies ye-seluplose ihla kwaye isakhiwo siba sesoser, esiluncedo kwinguqulelo yekhemikhali elandelayo.
Impendulo ye-Methylity: Indlela yokuphendula ye-methyyth iguqula imolekyuli eselselose ngokwazisa ngeqela le-methyl (-Ch). Iiarhente eziqhelekileyo ze-methylating zisebenzisa i-methyl chloride (ch₃cl) okanye i-chloroform (Chcl₃). Phambi kwe-sodium hydroxide, iarhente ye-methylating iphinda iphinde ithathe indawo ye-hydroxyl iqela le-hydroxyl (-------) kwimolekyuli ye-selselose kwimolekyuli ye-selselose nge-methyl amaqela (-Ch₃), ngaloo ndlela esenza i-methyl sellulose.
I-HYDROXYPROKITROPROORD: Emva kokuba i-methyyred igqityiwe, i-propylene oxide (PO) idla ngokusetyenziswa njengeqela elinolwazi lokwazisa iQela le-HydropylPropyPropyPropyl (-oh). Impendulo iqhutywa phantsi kweemeko ze-alkaline. Ukuphendula i-hydroxypropypropy ye-hydroxypropypropypropy iphinda ithathe indawo yamaqela e-mayikisi kwimolekyuli ye-selselose enamaqela e-hydroxypropy, ngaloo ndlela yenza i-HPMC.
Ulawulo lokuphendula: Ngexesha lokuphendula, ubushushu, ixesha kunye nomyinge we-rolecyplopy, isidanga se-Hydroxy ye-kimbacell® ye-Kimalictra® yemveliso ihlangabezana neemfuno zemveliso. Ngokubanzi, ubushushu bokuphendula bulawulwa phakathi kwe-30 ne-80 ° C, kwaye ixesha lokuphendula lisusela kwiiyure ezininzi ukuya kwiiyure ezilishumi.
Ukungathathi cala nokucocwa: Emva kokuphendula kuyagqitywa, imveliso kufuneka ihlanjululwe kwaye ihlanjululwe, njenge-acid acid, i-Hydrochloric Acid, njl.). Amanyathelo ococeko aquka ukuhlamba, ukucoca, ukomisa kunye nezinye iinkqubo zokususa izixhobo ezingafunekiyo, izinyibilikisi kunye neemveliso.
I-3. Imveliso yomile kwaye ipakishwe
Ukomisa: I-HPMC ecocekileyo ihlala ikho ngohlobo lomgubo onyibilikayo wamanzi, kwaye umswakama kufuneka ususwe yi-Spray ukomisa, uVuruum womisa kwaye ezinye iindlela. Imveliso eyomileyo kufuneka igcine umxholo wokufuma ophantsi, idla ngokulawulwa ngezantsi kwe-5%, ukuthintela imveliso ekuthandeni nasekuthambiseni.
Ukupakisha: I-HPMC eyomileyo ipakishwe kwifom powder, kwaye inkqubo yokupakisha ifuna unyango lokufuma. Ihlala ithelekiswa kwiingxowa zePolythylene, iingxowa zephepha okanye iingxowa zendlela yokuhambisa ngokulula kunye nokugcinwa.
4. Ukulawulwa komgangatho kunye nemigangatho yemveliso
Kwinkqubo yemveliso ye-HPMC, ulawulo olusemgangathweni lubalulekile. Umgangatho we-HPMC uxhomekeke kuphela kumgangatho wezinto ezingafunekiyo, kodwa nakwizinto ezinjengeemeko zokuphendula kunye neenkqubo zokwenza emva. Abavelisi badla ngokuqhuba uhlolo lwemigangatho ngokwemigangatho yamanye amazwe nezemimandla. Izalathisi eziqhelekileyo eziPhindiweyo zibandakanya:
I-Solidaity: i-HPMC kufuneka ibe ne-solinoility elungileyo, kwaye i-solidaity kunye nexabiso lokuchitheka kufuneka lifezekise iimfuno ezithile.
I-Viskosity: Uhlobo lwe-HPMC luchaphazela ngokuthe ngqo ukusebenza kwesicelo, kwaye iimveliso ezahlukeneyo zineemfuno ezahlukeneyo zokufakwa kwi-viscofity. Iindlela zokuphila eziqhelekileyo zovavanyo lweemvavanyo zibandakanya indlela yeBrookfield.
Ukucoceka kunye nokungcola: Umxholo wezinto ezinqabileyo kwiimveliso ze-HPMC kufuneka ulawulwe ngaphakathi kuluhlu oluchaziweyo ukuqinisekisa ubunyulu obuphezulu bemveliso.
Ubungakanani bentsalela: Kuxhomekeka kwiimfuno zemimandla eyahlukeneyo yesicelo, ubungakanani be-HPMC bungahluka, kwaye imigubo entle okanye iimveliso ezintle ziya kuba nemeko eyahlukileyo yesicelo.
I-5. IIMPENDULO ZE-HPMC
I-HPMC isetyenziswa ngokubanzi kumashishini amaninzi kwaye inexabiso elibalulekileyo lentengiso.
Ishishini lokwakha: I-HPMC isetyenziswa ngokubanzi njengearhente ye-tickener kunye nokugcina amanzi kwizixhobo zokwakha ezinje ngodaka lodaka, enodaka lommiselo kunye nokugcinwa kwamanzi.
Ishishini lamachiza: I-HPMC inezicelo ezibalulekileyo kwicandelo le-chibhu njenge-capsule goshells, iitafile ezinamachaphaza kunye nokulawulwa kweziyobisi.
Umzi-mveliso wokutya: Ukutya, i-HPMC isetyenziswa njenge-thickener, i-stabilizer, i-emulsifier, njl.
I-Cosmetic Ishishini: I-HPMC isetyenziswa njengearhente ye-tickener kunye nefilimu kwi-cosmetics, kwaye isetyenziswa ekwenzeni iimveliso ezifana ne-ores kunye neekhrim.
Amanye amasimi: I-KIMEACLLG®HPMC isetyenziswa ngokubanzi kumashishini anjengePetroleum, amaphepha, iphepha kunye neengubo.
Ukuveliswa kwemveliso yeI-HPMCUkuguqula isellulose yendalo kwi-polymer ye-polymer ye-pullymer ehambelana nepropathi yezinto ezininzi ngothotho lwezinto zokuguqulwa kwekhemikhali. Ngokulawula ngokuthe ngqo kwiimeko zokuphendula kunye neenkqubo zonyango emva, iimveliso ze-HPMC ezihlangabezana neemfuno ezahlukeneyo zesicelo zingafumaneka. Ukusetyenziswa okubanzi kwe-HPMC, ngakumbi uphando oluninzi kunye nophando oluthe kratya kunye nezinto zetekhnoloji ziya kuqhubeka nokukhuthaza ukuphuculwa kwenkqubo yayo yemveliso kunye nomgangatho wemveliso.
IXESHA LOKUQALA: UJAN-27-2025