Ukuziqulatha udaka ngokwakho yinto yesixhobo sokwakha esiqhele ukusetyenziswa kulwakhiwo lomhlaba. Inolwelo oluhle, i-adheir eyomeleleyo kunye ne-shrinkini ephantsi. Izithako zayo eziphambili zibandakanya isamente, i-aggregate elungileyo, iimodyuli kunye namanzi. Njengoko iimfuno zeshishini lokwakha zokusebenza kakuhle kunye nomgangatho ziyaqhubeka nokunyuka, udaka lokuzibandakanya oziqulunqwa luhlala lunqunyanyiswa zizinto ezinje ngolwelo, ukunamathela kunye nokunyangwa.
I-HPMC yinto ye-polymer esekwe kwiseluplose kwaye yenziwe ngokuguqulwa kwemithombo yeekhemikhali. Inomoya ofanelekileyo wamanzi, iipropathi zokugcina amanzi kunye nokugcina amanzi. Ukusetyenziswa kwayo kwi-purmac yokuzihlisa kunokuphucula ukusebenza ngokukuko, ukunganyangeki, ukusebenza kwendawo yokugcina amanzi, njl njl.
1. Iipropathi ezisisiseko ze-HPMC
I-HPMC yi-polymer ye-polymer ye-polymer elungiselelwe ngokuyizisa nge-methyl kunye namaqela e-hydroxypropy kwiimolekyuli. Inezinto ezibonakalayo zilandelayo:
Ukutyibilika: I-kimbacell®hpmc inokunyusa kakhulu i-viscomosity yesisombululo, ngaloo ndlela ukulungelelanisa ulwelo lodaka lokuziqokelela.
Ukugcinwa kwamanzi: i-HPMC inokugcina umswakama eluphangweni, kuphephe ukufika ngokukhawuleza komswakama, kwaye uqiniseke ukuba ne-hydration ye-hydration yesamente.
Ulawulo: Ukudityaniswa kwe-HPMC kunokuphucula ukusebenza kodaka, kwenza udaka luhamba phantsi komhlaba kwaye luphephe iibhloksi kunye neebhubhu.
Umbembeko: Ingaphucula i-adhesion phakathi kodaka kunye nomgangatho owona mgangatho kwaye iphucule ubumbisi bodaka lokuziqokelela.
2. Ifuthe elithile le-HPMC kwintsebenzo yodaka lokuzimela
I-fluindity kunye neepropathi zokwakha
I-HPMC, njenge-thi chickerer, inomsebenzi wokuphucula ulwahlulelo kwi-fert. Ulwelo yipropathi ebaluleke kakhulu ekwakhiweni kokuziqumanda ngodaka, echaphazela ukugudla kunye nesantya sokwakha. Izifundo zibonakalise ukuba isixa esifanelekileyo se-HPMC sinokuphucula udaka lodaka, senza kube lula ukulala, ngelixa siphepha ukuhamba okungathethekiyo okuthe tyaba. Ngokulawula isixa se-HPMC, udaka lodaka lunokuhlengahlengiswa ukuqinisekisa ukuba aluyi kuphulukana nolwelo okanye luthambile kakhulu, ngaloo ndlela ukuphuculwa kokusebenza ngokukuko.
Ukugcinwa kwamanzi
Ukugcinwa kwamanzi i-HPMC yenye inzuzo ebalulekileyo kwisicelo sayo kwi-duct. Ukufuma komswakama ekuziqokeleleni udaka ngokwakho kuya kuphulukana nokuphuma ngexesha lenkqubo yokwakha. Ukuba umswakama ulahlekile ngokukhawuleza, inokubangela udaka kwaye ubukele udaka, kwaye ichaphazela inkqubo ye-qudration yesamente. I-HPMC inokulibazisa ngempumelelo ukuvela kwamanzi ngokwenza i-hydration, eqinisekisa ukuba i-hydration impendulo yesamente inokuqhubeka ngokupheleleyo. Oku kungaluthintela umxholo omanzi ngenxa yokomisa ngokukhawuleza kwaye unciphise imifula kunye neziphene ngexesha lolwakhiwo.
Ukunganyangeki
Ukuziqulatha u-Arurr rhoqo uhlala ejongene nengxaki yokuqhekeza okubangelwa kukuncitshiswa okanye utshintsho lobushushu. Ukongezwa kwe-kimbacell®hpmc kunokuphucula ukugcinwa kwamanzi kodaka, kulibazise ukuvela kwamanzi, kwaye kunciphise ukuntywila kodaka, ngaloo ndlela kuphuculwe ukumelana nokunganyangeki. Isakhiwo se-phuclor se-HPMC sinokwenza inkqubo yokusasazeka i-qumerix matrix, iphazamise i-shrinking engalinganiyo ngexesha lenkqubo yokomisa, kwaye inciphise i-rocks.
Umlinganiso
UVIKILE OKANYE I-HPMC inceda ekuphuculeni ukunamathela kodaka, ngakumbi i-birmation enendawo yokuhlala ngexesha lenkqubo yokubhaka. Omnye wemisebenzi ephambili yokuziqokelela ngokwakho kukulinganisa umhlaba kwaye ubonelele ngokutsala oqinileyo. I-HPMC inokuphucula umbilini phakathi kodaka kunye nomhlaba, nqanda into embi phakathi kwendlela yokuzimela kunye nomlinganiso wesiseko, ngaloo ndlela ukuphuculwa komgangatho wokwakha. .
Iipropathi ezichasene nenqanaba
Ukuqhutywa kunye nokulawula i-foam yodaka ngokwakho Isakhiwo se-geculari se-HPMC sinokunceda ukunciphisa ukuthathwa komoya elufayoni, kuphephe ukusekwa kweebhubhu, kwaye uqiniseke ukuba ulungelwanga kunye nobungqingqwa bomhlaba. Ngokuphucula iipropathi zenqanaba lodaka lokuzihlisa, i-HPMC inokuqinisekisa ukuba isiphumo sokuzibandakanya nobukhosi benqanaba elikhulu kunye nokuphucula umgangatho wemveliso egqityiweyo.
I-3. Ukuphuculwa kwe-HPMC Dosage
Nangona i-HPMC ineziphumo ezilungileyo ekusebenzeni kokuzimela udaka, ukukhetha idosi yayo kubaluleke kakhulu. I-HPMC eninzi iya kwenza udaka kunye nokuchaphazela ulwahlulo; Ngelixa i-HPMC incinci kakhulu ayiyi kuba nakho ukugqiba ngokupheleleyo iziphumo. Ke ngoko, isixa esifanelekileyo se-HPMC esongeziweyo kufuneka silungiswe ngokweendlela ezahlukeneyo kunye neemfuno zokwakha. Ngokubanzi, isixa esifanelekileyo se-HPMC songezwa siphakathi kwe-0.1% ne-0,5%, kwaye umlinganiso othile kufuneka ufaneleke ngokweemfuno zentsebenzo zodaka.
Njengesimo sengqondo esibalulekileyo,Hydroxypropyl methylcelceluplose(I-HPMC) inefuthe lokuphucula intsebenzo xa isetyenziswa ekuziqokeleleni udaka lokuzibandakanya. Ingaphucula ubulwele, ukugcinwa kwamanzi, ukunganyangeki kunye nokunamathela kodaka. Isixa esifanelekileyo se-kimbacell®HPMC sinokuphucula ngokufanelekileyo ukusebenza kunye nobomi benkonzo wokuziqokelela udaka, kuyaqhubeka nokuhlangabezana neemfuno eziphezulu zeshishini lokwakha kunye nokusebenza kakuhle. Ke ngoko, kwi-fortion yoyilo lodaka lokuzihlisa, ukusetyenziswa kwe-HPMC yindlela ebalulekileyo yobugcisa. Nangona kunjalo, umthamo we-HPMC kunye nohlengahlengiso lwefomula kufuneka ilungiselelwe ngokweemeko ezithile zokwakha kunye neemfuno zomsebenzi ukufezekisa eyona ndlela ilungileyo yokwakha.
I-Post Time: Jan-18-2025