tsebisa
Hydroxypropyl methylcellulose (HPMC) ke selulose ether e qhibilihang ka metsing e atisang ho sebelisoa lits'ebetsong tse fapaneng tse kang kaho, lijo, meriana le litlolo ka lebaka la thepa ea eona e ikhethang e kang ho boloka metsi, ho teteaneng le ho etsa lifilimi. Thepa ea ho boloka metsi ea HPMC e bohlokoa haholo kahong kaha e thusa ho ntlafatsa ts'ebetso, ho fokotsa ho petsoha le ho matlafatsa ts'ebetso ea lisebelisoa tse thehiloeng ho samente. Ka hona, ho lekanya ka nepo matla a ho boloka metsi a HPMC ho bohlokoa ho netefatsa boleng ba sehlahisoa sa ho qetela. Sehloohong sena, re tla tšohla mokhoa oa tlhahlobo ea ho boloka metsi oa HPMC le bohlokoa ba ona indastering ea kaho.
Mokhoa oa teko ea ho boloka metsi
Bokhoni ba ho ts'oara metsi ba HPMC bo lekantsoe ka bongata ba metsi ao HPMC e ka a bolokang ka nako e itseng. Ho na le mekhoa e mengata ea ho leka ho boloka metsi a HPMC, mokhoa o sebelisoang haholo ke mokhoa oa centrifugation. Mokhoa ona o na le mehato e meraro ea mantlha:
Mohato oa 1: Tokiso ea Mohlala
Mohato oa pele ke ho lokisa sampole ea HPMC. Beha palo e itseng ea phofo ea HPMC esale pele 'me u kenye metsi a mangata ho etsa slurry. Karolelano ea HPMC ho metsi e fapana ho latela litlhoko tse ikhethileng tsa kopo le tlhahlobo. Leha ho le joalo, karolelano e tloaelehileng ke 0.5% HPMC ho metsi ka boima ba 'mele. The slurry e lokela ho tsosoa metsotso e 'maloa ho netefatsa hore HPMC e hasane ka ho lekana ka metsing. Ebe, tlohela slurry hore e lule lihora tse 12 ho netefatsa hore e na le metsi ka botlalo.
Mohato oa 2: Centrifuge
Ka mor'a lihora tse 12, tlosa slurry 'me u behe boima bo tsejoang ba slurry ka har'a tube ea centrifuge. Joale tube e kenngoa ka har'a centrifuge ebe e ohloa ka lebelo le itseng ka nako e behiloeng. Lebelo le nako ea centrifugation li ka fapana ho latela mokhoa o khethiloeng. Ka kakaretso, lebelo la centrifuge ke 3000rpm mme nako ea teko ke metsotso e 30. Leha ho le joalo, litekanyetso tse fapaneng li ka hloka lebelo le nako e fapaneng.
Mohato oa 3: Palo ea boleng ba ho boloka metsi
Ka mor'a centrifugation, tlosa tube 'me u arole metsi ho tloha ho HPMC. Boleng ba ho boloka metsi bo ka baloa ka tsela e latelang:
Boleng ba ho boloka metsi = [(HPMC + boima ba metsi pele ho centrifugation) - (HPMC + boima ba metsi ka mor'a centrifugation)] / (HPMC + boima ba metsi pele ho centrifugation) x 100
Boleng ba ho boloka metsi bo bontša palo ea metsi a bolokiloeng ke HPMC ka mor'a centrifugation.
Bohlokoa ba tlhahlobo ea ho boloka metsi kahong
Teko ea ho boloka metsi e bohlokoa indastering ea kaho kaha e thusa ho etsa bonnete ba hore sehlahisoa sa ho qetela ke sa boleng bo ts'oanang 'me se kopana le litlhaloso tse hlokahalang. HPMC e atisa ho sebelisoa linthong tse entsoeng ka samente tse kang seretse, grout le konkreite ho ntlafatsa ts'ebetso ea tsona, ho fokotsa ho honyela le ho eketsa nako e telele. Thepa ea ho boloka metsi ea HPMC e bapala karolo ea bohlokoa ho fihlelleng melemo ena.
Boleng ba ho boloka metsi ba HPMC bo etsa qeto ea hore na metsi a ka bolokoa ka har'a thepa e thehiloeng ho samente, e leng se tlatsetsang ho sebetsa ha eona. Lisebelisoa tsa samente tse nang le boleng bo phahameng ba ho boloka metsi li khoneha ebile li bonolo ho li kopanya le ho li sebelisa. Ho phaella moo, lisebelisoa tse nang le boleng bo phahameng ba ho boloka metsi li na le lipokotho tse fokolang tsa moea, tse fokotsang monyetla oa ho senya le ho eketsa nako e telele ea thepa.
Ho feta moo, boleng ba ho boloka metsi ba HPMC ke sesupo sa boleng ba HPMC bo sebelisitsoeng ho thepa. HPMC e nang le thepa e hlokahalang ea ho boloka metsi e netefatsa ts'ebetso ea nako e telele ea thepa ea mohaho. Ka lehlakoreng le leng, HPMC e nang le litekanyetso tse tlaase tsa ho boloka metsi e ka lebisa ho thepa e sa lekaneng ea kaho, ho ba le maqhama a fokolang le ho fokotseha, ho lebisang ho hloleheng ha thepa ea mohaho.
ha re phethela
Teko ea ho boloka metsi ke ntlha ea bohlokoa ho fumana boleng ba HPMC e sebelisoang indastering ea kaho. Teko ena e thusa ho lekanya ka nepo thepa ea ho boloka metsi ea HPMC ho netefatsa hore e fihlela litlhoko tse ikhethileng tsa ts'ebeliso e fanoeng. HPMC e na le polokelo e phahameng ea metsi, e fana ka ts'ebetso e ntlafetseng, likamano tse ntlafetseng, ho fokotsa ho phunyeha le ho eketsa nako e telele ho thepa ea samente. Ka hona, indastering ea kaho, hoa hlokahala ho etsa liteko tsa ho boloka metsi ho HPMC ho netefatsa boleng ba sehlahisoa sa ho qetela.
Nako ea poso: Sep-18-2023