Tšebeliso ea CMC ho Meriana

Carboxymethyl cellulose (CMC) ke polymer e qhibilihang ka metsi e tsoang selulose, e sebelisoang haholo indastering ea bongaka ka lebaka la thepa ea eona e ikhethang, joalo ka biocompatibility, non-toxicity, le bokhoni bo botle ba ho khomarela mucoadhesive. Sengoliloeng sena, re tla tšohla lits'ebetso tse fapaneng tsa CMC ho tsa bongaka.

1. Ophthalmic dikopo: CMC e ho pharaletseng sebelisoa ka litokisetso ophthalmic, tse kang marotholi a mahlo le mafura a, ka lebaka la matla a eona a ho eketsa nako ea ho lula ea lithethefatsi ka holim'a ocular, ka tsela eo ho ntlafatsa bioavailability lona. CMC e boetse e sebetsa e le setsi se teteaneng mme e fana ka lubrication, ho fokotsa ho teneha ho bakoang ke ho sebelisoa ha moriana.
2. Pholiso ea maqeba: Li-hydrogel tse thehiloeng ho CMC li entsoe bakeng sa lits'ebetso tsa ho folisa maqeba. Li-hydrogel tsena li na le metsi a mangata 'me li fana ka tikoloho e mongobo e khothalletsang pholiso ea maqeba. Li-hydrogel tsa CMC le tsona li na le biocompatibility e ntle haholo 'me li ka sebelisoa e le scaffolds bakeng sa kholo ea lisele le lisele.
3. Phano ea lithethefatsi: CMC e sebelisoa haholo lits'ebetsong tsa phano ea lithethefatsi, joalo ka li-microspheres, nanoparticles, le liposomes, ka lebaka la ho lumellana ha eona, ho senyeha ha lintho, le thepa ea mucoadhesive. Sistimi ea phano ea lithethefatsi e thehiloeng ho CMC e ka ntlafatsa bioavailability ea lithethefatsi, ea fokotsa chefo ea tsona, 'me ea fana ka phano e lebisitsoeng ho lisele kapa litho tse itseng.
4. Ts'ebeliso ea mala: CMC e sebelisoa ha ho etsoa matlapa le li-capsules ho ntlafatsa thepa ea tsona ea ho qhibiliha le ho qhalana. CMC e boetse e sebelisoa e le se tlamella le ho qhalana ha ho etsoa matlapa a qhalang ka molomo. CMC e sebelisoa ha ho etsoa suspensions le emulsions ho ntlafatsa botsitso ba bona le viscosity.
5. Lisebelisoa tsa meno: CMC e sebelisoa mekhoeng ea meno, joalo ka sesepa sa meno le molomo, ka lebaka la bokhoni ba eona ba ho fana ka viscosity le ho ntlafatsa thepa ea ho phalla ha motsoako. CMC e boetse e sebetsa e le tlamahano, e thibelang karohano ea likarolo tse fapaneng tsa sebopeho.
6. Lits'ebetso tsa botšehali: CMC e sebelisoa mefuteng ea botšehali, joalo ka li-gel le litlolo, ka lebaka la thepa ea eona ea sekhomaretsi. Metsoako e thehiloeng ho CMC e ka ntlafatsa nako ea ho lula ha moriana ka har'a mucosa ea botšehali, ka hona ho ntlafatsa bioavailability ea eona.

Qetellong, CMC ke polymer e feto-fetohang e nang le mefuta e mengata ea lits'ebetso ho tsa bongaka. Lintho tsa eona tse ikhethang, tse kang biocompatibility, non-toxicity, le bokhoni ba ho khomarela mucoadhesive, e etsa hore e be motsoako oa bohlokoa litokisetsong tsa mahlo, ho folisa maqeba, mekhoa ea ho fana ka lithethefatsi, ho etsoa ha mala, ho etsoa ha meno, le litokisetso tsa botšehali. Tšebeliso ea litlhare tse thehiloeng ho CMC e ka ntlafatsa bioavailability ea lithethefatsi, ea fokotsa chefo ea tsona, 'me ea fana ka phano e lebisitsoeng ho lisele tse itseng kapa litho tsa 'mele, kahoo ea ntlafatsa liphello tsa mokuli.