Habka wax soo saarka HPMC

Habka wax soo saarka ee loogu talagalayHydroxypropyl methylrcellesulose (HPMC)waxay ku lug leedahay taxane kiimiko, farsamada, iyo tillaabooyinka kuleylka. Hawshu waxay ku bilaabmaysaa unugyada celling cluew oo ka soo jeeda fiiska dabiiciga ah waxayna ku dhammaataa soosaarka ganaax, budo qalalan oo ku habboon codsiyada kala duwan. Guudmar faahfaahsan ayaa daboolaya tallaabo kasta oo ka mid ah nidaamka wax soo saarka ee HPMC, oo ay ku jiraan burburka marxaladaha muhiimka ah, alaabada ceyriinka, iyo tallaabooyinka xakamaynta tayada.

Hordhac wax soosaarka HPMC

Hydroxypropyl methylrcellulose(HPMC) waa in ether chetherka loo isticmaalo codsiyo kala duwan, oo ay kujirto dhismaha lagu daro (tusaale ahaan, aaladda lagu daro ama la-dagaallanka. Guryaheeda u gaarka ah waxaa ka mid ah haynta biyaha, awoodda sameynta filimka, viscosity sare, iyo fududeynta wax ka badalida.

HPMC waxaa lagu abuuray iyada oo loo badalo chemplules-ka kaadida, polymer dabiici ah oo laga soo saaray fiilooyinka dhirta. Iyada oo loo marayo geedi socodka dhiiga, kooxo gaar ah oo shaqeynaya-methylyliyohydroxypropylKooxaha-waxaa loo soo bandhigaa moleekul-ka-buugga unugyada, sidaasna wax looga beddelo astaamaha jir ahaaneed iyo kiimikada. Wax ka badashadaani waxay soo rogaan astaamaha loo baahan yahay sida silsiladaha biyaha, qulqulka qulqulka, iyo guryaha lagu xiro sheyga.

Qeybaha soosocda waxay bixiyaan burburin faahfaahsan oo ah tillaabooyinka ku lug leh soosaarka HPMC, oo daboolaya diyaarinta cayriin, hanaanka kiimikada, iyo tillaabooyinka wax soo saarka ka dib.

1. Diyaarinta ceew

Waxyaabaha ugu horeeya ee cayriin ee wax soo saarka HPMC waakaadida-u-duuban, kaas oo laga soo xigtay fiilooyinka dhirta, ugu horrayn alwaax alwaax ama suuf cudbi ah. Cellulose waa inuu maraa daaweyn taxane ah si meesha looga saaro ciladaha oo loo diyaariyo geedi socodka 'Etherent'. Tani waxay xaqiijineysaa in unugyadu ay nadiif tahay oo falcelin tahay.

1.1. Sourcing iyo nadiifinta cudurka cellulose

Fikrada unugyada ayaa laga shaqeeyaa oo la qalajiyaa si loo gaaro waxyaabo gaar ah oo qoyaan gaar ah, oo muhiim u ah talaabooyinka xiga.

1.2. Daaweynta hore ee alkali

Fikers-ka cudurka unugyada waxaa lagu daaweeyaa sodium hydrouxide (NaOh) xalka si ay u sameeyaan kuwa wax ku faafaya oo ay furayaan qaabkooda. Tan waxaa loo yaqaanDaaweynta Alkali or firfircoonida, waana talaabo muhiim u ah hawsha.

2. Habka Ethethility

Qaadaalku waa geedi socodka uu cellulose uga falceliyomethyl chloride (ch₃l)iyopropylene oxide (c₃h₆o)Si loo soo bandhigo methyl (ch₃) iyo hydroxypropyl (c₃h₆oh) kooxaha, u beddelashada unugyada unugyadaHydroxypropyl methylrcellesulose (HPMC).

Tani waa marxaladda ugu halista badan ee wax soo saarka HPMC, maadaama ay go'aamiso tayada iyo astaamaha ee sheyga ugu dambeeya.

2.1. Methylation (methyl group dheeraad ah)

Fikradaha unugyada unugyada ayaa marka hore falcelinayamethyl chlorideJoogitaanka saldhigga (badiyaa sodium hydroxide, NaOH), oo ku soo bandhigaya kooxaha methyl (-ch₃) ee qaab dhismeedka unugyada.

Qaddarka methylation ayaa go'aamisa Theheerka beddelka (ds), taas oo saameysa xaruuda iyo aragtida sheyga ugu dambeeya.

2.2. Hydroxypropylation (hydroxypropyl koox ahaan)

Cilmiga unugyada ayaa markaa ka falgalayapropylene oxide (c₃h₆o)si loo soo bandhigoKooxaha hydroxypyl (-c₃h₆oh), kuwaas oo siiya HPMC astaamaha dabeecaddiisa, sida culeyska biyaha iyo viscosity.

Heerka hydroxypropyl bedelka ayaa sidoo kale saameyn ku leh astaamaha ugu dambeeya ee HPMC, sida cod-gashi, karti, iyo awooda abuurista filimada.

2.3. Xakamaynta jawaab celinta

Falcelinta Ethelt-ka ayaa caadi ahaan lagu sameeyaa aVestortor ArcresshoosHeerkulka la xakameeyo iyo cadaadiska. Xaaladaha caadiga ah waa sida soo socota:

Fal-celinta waa in si taxaddar leh loo xakameeyaa si loo hubiyo labiska labiska oo iska ilaali jawaab celin aan dhammaystirnayn.

3. Qiyaasta iyo maydhista

Hawsha ka dib, isku-darka jawaab celinta waxaa ku jira kiimikooyin xad-dhaaf ah oo aan la koobi karin iyo kiimikooyin aan la koobi karin. Kuwani waxay u baahan yihiin in laga takhaluso oo laga saaro si loo hubiyo in sheyga ugu dambeeya ee HPMC uu amaan yahay, saafi yahay, oo uu buuxiyo faahfaahinta.

3.1. Ka beddelid

3.2. Meyd ku socodka

4. Qalajinta iyo budada

MarHPMCSlurry waa ka takhalusaa oo la sifeeyaa, tallaabada xigta ayaa qalajinaysa si loo beddelo sheyga budo ganaax ah. Hawsha qalajinta ayaa si taxaddar leh loo xakameeyaa si loo ilaaliyo astaamaha kiimikada ee HPMC.

4.1. Qalajin

4.2. Shiidida iyo raadinta

5. Xakamaynta Tayada iyo Imtixaanka

Kahor inta badeecada ugu dambeysa ee HPMC ay xirmalan tahay oo la rabo, waxaa lagu shubaa, waxaa lagu buufiyaa tijaabooyin xakameyn adag oo tayo badan oo tayo leh si loo hubiyo in ay la kulanto heerarka warshadaha.

5.1. Baadhitaanka viscosity

5.2. Qoraaga nuxurka

5.3. Daahirnimada iyo baaritaanka wasakhda ah

6. Baakadaha

Mar haddii HPMC ay dhaafto dhammaan imtixaannada kontaroolada tayada leh, waxaa loo xiraaBoorsooyinka, durdadka durbaanamaxaynWaxay kuxirantahay shuruudaha macaamiisha.

Gabagabo

Geedi socodka waxsoosaarka ee ku saabsan hydroxypropylkylkellellase (HPMC) waxay ku lug leedahay dhowr marxaladood oo si taxaddar leh loo xakameeyay, oo laga bilaabo socodka iyo nadiifinta unugyada unugyada ugu dambeeya ee sheyga. Tallaabo kasta oo hawsha ku jira wuxuu saameyn ku yeeshaa tayada iyo astaamaha HPMC, sida viscosity, xadhigoodu yahay, iyo kartida qaab-dhismeedka filimka.

Fahmitaanka nidaamka si faahfaahsan ayaa loo hubin karaa in soosaarayaasha ay kor u qaadi karaan marxalad kasta si ay u soo saarto shey tayo sare leh oo buuxiya baahiyaha warshadaha kala duwan, laga bilaabo dhismaha dawooyinka.