Hydroxypropyl MethylCellulose(HPMC) soo saaraha
CAS: 9004-65-3
Hydroxypropyl MethylCellulose (HPMC) amahypromellosewaa biyo milmi methyl cellulose ether, taas oo si weyn loogu isticmaalo dhismaha, farmashiyaha, cuntada, qurxinta, saabuunta, rinji, sida dhumuc weyn, emulsifier, film-hore, binder, wakiilka kala firdhiso, colloid.We ku siin kartaa heerka caadiga ah HPMC, waxaan sidoo kale waxay ku siin kartaa HPMC wax laga beddelay iyadoo la raacayo shuruudaha macaamiisha. Ka dib markii la hagaajiyay iyo daaweynta dusha, waxaan heli karnaa alaabta kuwaas oo si degdeg ah ugu firdhiyey biyaha, dheereeyaan wakhtiga furan, anti-sagging, iwm.
Muuqashada | Caddaan ama budo cad |
Methoxy (%) | 19.0 ~ 24.0 |
Hydroxypropoxy (%) | 4.0 ~ 12.0 |
pH | 5.0 ~ 7.5 |
Qoyaanka (%) | ≤ 5.0 |
Hadhaaga shilka (%) | ≤ 5.0 |
Heerkulka galalka (℃) | 70 ~ 90 |
Cabbirka walxaha | min.99% waxay maraan 100 mesh |
Darajada caadiga ah | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
HPMC MP400 | 320-480 | 320-480 |
HPMC MP60M | 48000-72000 | 24000-36000 |
HPMC MP100M | 80000-120000 | 40000-55000 |
HPMC MP150M | 120000-180000 | 55000-65000 |
HPMC MP200M | 160000-240000 | Min70000 |
HPMC MP60MS | 48000-72000 | 24000-36000 |
HPMC MP100MS | 80000-120000 | 40000-55000 |
HPMC MP150MS | 120000-180000 | 55000-65000 |
HPMC MP200MS | 160000-240000 | Min70000 |
Codsiyada caadiga ah ee HPMC:
Xabagta Dusha
●Biyo haynta wanaagsan: wakhtiga furitaanka oo dheeraada waxa ay ka dhigi doonta wax-ku-oolnimo badan.
●Adhesion iyo caabbinta simbiriirixidda oo hagaagtay: gaar ahaan tiirarka culus.
●Shaqeynta ka sii wanaagsan: dufanka iyo balaastiga ayaa la hubiyaa, hoobiye si fudud oo degdeg ah ayaa loo marsiin karaa.
Malaasta sibidhka / hoobiye isku darka qallalan
●Qaabaco qallalan oo fudud oo isku dhafan oo ay ugu wacan tahay milanka biyaha qabow: samaynta kuusku si fudud ayaa looga hortagi karaa, oo ku habboon tiirarka culus.
● Biyo-hayn wanaagsan: ka-hortagga luminta dareeraha ee substrate-ka, waxa ku habboon biyaha ku jira waxaa lagu hayaa isku dar taas oo dammaanad qaadaysa waqti dheer oo isku-ururin.
●Baahida biyaha oo korodhay: wakhtiga furan oo kordhay, aagga spry oo la balaariyay iyo qaabaynta dhaqaale oo badan.
●Faafinta fudud iyo iska caabbinta hoos u roonaanta sababtoo ah joogteynta oo soo hagaagtay.
darbiga derbiga
●Biyaha haynta: la kordhiyo waxa ku jira biyaha ku jira slurry.
●Ka-hortagga-soo-baxa: marka la faafinayo jiingado jaakad dhumuc weyn leh waa laga fogaan karaa.
●Dharka hoobiyeyaasha oo kordhay: iyadoo ku xiran culeyska isku dhafka qalalan iyo qaabeynta habboon, HPMC waxay kordhin kartaa mugga hoobiye.
Nidaamka Dhamaystirka iyo Dahaarka Dibadda (EIFS)
●Adhesion oo la hagaajiyay.
●Awoodda qoynta wanaagsan ee looxa EPS iyo substrate.
●Waxa yaraaday gelitaanka hawada iyo qaadashada biyaha.
Is-kala-qaadid
●Ka ilaalinta qulqulka biyaha iyo wasakhowga maadada.
●Wax saameyn ah kuma laha dareeraha dareeraha leh ee mawgu hooseeyo
HPMC, iyadoo sifooyinkeeda xajinta biyaha ay hagaajinayaan waxqabadka dhamaadka dusha sare.
Filler dildilaaca
●Shaqeynta ka sii wanaagsan: dhumucda saxda ah iyo caagagga.
●Biyo-hayntu waxay hubisaa wakhtiga shaqada oo dheer.
●Sag caabbinta: awoodda isku xidhka hoobiye oo roonaaday.
Codsiga cuntada ee dawooyinka iyo cuntada:
Isticmaalka | Darajada badeecada USP/EP/E464 | Qiyaasta |
Bulk Laxative | HPMC K4M,HPMC K100M | 3-30% |
Kareemada, jel | HPMC E4M,HPMC F4M,HPMC K4M | 1-5% |
Diyaarinta Indhaha | HPMC E50 | 01.-0.5% |
Diyaargarowga dhibcaha indhaha | HPMC E4M, HPMC F4M, HPMC K4M | 0.1-0.5% |
Wakiilka shaqada ka joojinaya | HPMC E3, HPMC E5 | 1-2% |
Antacids | HPMC E50, HPMC F50 | 1-2% |
Kiniinnada ku xidha | HPMC E5, HPMC E100 | 0.5-5% |
Convention Qoyan Granulation | HPMC E5, HPMC A4C | 2-6% |
Dahaarka kiniinka | HPMC E5, HPMC E15 | 0.5-5% |
Matrix siidaynta la xakameeyey | HPMC K100 ,HPMC K100M | 20-55% |
Baakad:
Alaabada HPMC waxa ay ka buuxaan saddex bac oo xaashi ah oo ay ku jirto bac polyetylen ah oo gudaha ah oo la xoojiyay, miisaanka saafiga ahi waa 25kg kiishadiba.
Kaydinta:
Ku hay bakhaar qallalan oo qabow, kana fog qoyaanka, qorraxda, dabka, roobka.