Hydroxyprupyl methylcellose (HPMC)is cellulose inobviswa zvakanyanya kushandiswa mune yemishonga, chikafu, maindasitiri ekuvaka uye ekuvaka. Chemakemikari chemoyo chine hydroxyprupyl uye methyl mapoka, uye mashandiro azvo madiki, eting.
1. Zvinoreva HPMC uye HPMCS
Musiyano mukuru pakati peHPMC uye hpmcs nderwe "s" muZita rekupedzisira rinomiririra "boka reSulfate" riri muzvimwe, mune zvimwe zviitiko, hpmc radivives rinowedzera mapoka ekusawedzera kuti awedzere maitiro avo echokwadi.
HPMC: Iyi ndiyo standard hydroxyropropyl methylcellose, iyo isina mapoka ekusuwa. Izvo zvinowanzoshandiswa mune zvekudya, mushonga, cosmetics, kuvakwa uye kune mamwe minda, uye kune zvinhu zvakakosha zvakadai sekuremerwa, kuumbwa kwemafirimu, uye kupararira. HPMC ndeyekubatanidzwa kwehydroxypropyl uye methyl mapoka, uye viscosity yayo, solubility uye rheology inogona kudzorwa nekugadzirisa madhigirii akasiyana ekutsvaga.
HPMCS: HPMCS ndeye hydroxypropyl methylcellose sulfate ine sulfate mapoka. Iyo "s" inomiririra maitiro ekusuwa, ayo anowanzoita kuti chinhu chacho choupfu hydrophilic, uye kugadzikana uye viscosity mumhinduro inogona kunge yakasiyana. HPMC inowanzoshandiswa mumamiriro ezvinhu anoda kukwidziridzika kumusoro uye chaiyo yemakemikari yekugadzirisa, yakadai semunda wemishonga.
2. Makemikari maitiro akasiyana
Chemical chimiro cheHPMC inonyanya kubva pane cellulose, iyo inoshandurwa nemethylation uye hydroxyprupropropylation. Chimiro chayo chine yakakwira mvura solubility uye inogona kuumba mhinduro yemvura mumvura.
Chemakesi yemakemikari eHPMC ine HPMC pamwe nekutanga kwemapoka ane sulfate, ayo anochinja hydrophilikuti yayo uye kushanda mune mamwe marudzi ekunyora emvura. Nhungamiro yemapoka ane sulfate inobatsira kuwedzera hydration yayo uye inogona kukanganisa huwandu hwayo hwekunyungudika kana zvimiro zvakatsikirira pasi pemamwe mamiriro ezvinhu.
3. Kuita kwemisiyano
Solubility: HPMC inowanzo nyungudika mumvura kuti iite viscous mhinduro uye ine yakanaka visco gadziriso. Yayo solubility uye viscosity inogona kugadziriswa sezvazvinodiwa, sekudzora kushamwaridzana kwayo nemvura uye zvivakwa zvezvinyorwa zvinoratidzwa mumhinduro dzakasiyana.
Kugadzikana: HPMCS yakawedzera hydrophilicity nekuda kwekutanga kwemapoka ane shungu, ayo anogona kupa kugadzikana kuri nani mune zvimwe zvigadzirwa zvemishonga kana zvechinyakare. Mukuwedzera, mapoka anokudzwa anogona kuitawo Kimcell®hpmcs akagadzikana pasi pemamwe mamiriro ezvinhu, akadai seyakaomerera kana kuchinja ph kukosha, uko Hpmcs inogona kuratidza kushivirira kwakasimba.
Biocomprifiilation: Seyakanyanya kushandiswa pharmaceucient, HPMC yakagadzirirwa zvizere kuti isimbe yayo uye kuchengeteka mumunda wemishonga. Nekudaro, nekuda kwekuwedzera kwemapoka ane sulfate, HPMPS zvinogona kuda zvimwe zvechokwadi zvidzidzo mune zvimwe zvinonyadzisa.
4. Masvondo ekushandisa
HPMC: Inoshandiswa zvakanyanya muMishonga (seyakasimudzirwa-inosunungura zvinodhaka, mahwendefa ehembe), cosmetics, kuvakwa, chikafu uye mamwe maindasitiri. Yayo isiri-yepfuma, hypoallergenicity uye yakakwirira biocomputer inoita kuti ive yakajairika thickener, firimu raimbova uye stabilizer mune maindasitiri emishonga uye ekudya.
HPMCS: Nekuda kwezvinhu zvaro zvakakosha zvemakemikari uye solubility maitiro, HPMCS inonyanya kushandiswa mune zvimwe zvinoda mishonga yemishonga, kunyanya kugadzirira kwemishonga yakasimudzirwa. HPMC inowanzoshandiswa mune zvinodhaka zvekusunungurwa-vanodhakwa-vamiriri uye zvakananga zvinodhaka zvinodhaka, uye dzimwe nguva zvinoshandiswa mukuwedzera kwekudya.
5. Zvakajairika Zvigadzirwa Zvinyorwa
HPMC uye HPMCs ine huwandu hwakawanda hwezvigadzirwa zvakanyorwa, izvo zvinowanzo kuvezwa zvichienderana nemifananidzo yakadai sehuremu hwemanyorerwe, degree rekutsika, uye solubility. Zvigadzirwa zvevakasiyana zvirevo zvinoratidza kuita kwakasiyana mumashandisirwo akasiyana.
HPMC ine madhigirii akasiyana ezipi, akasiyana zvisizvo uye simba, uye rakakodzera kuminda dzakasiyana. Zvakafanana zvakataurwa zvinosanganisira yakaderera viscosity, pakati vevistity, yakakwira viscosity, nezvimwe.
Zvinyorwa zveHPMC zvinonyanya kukamurwa zvinoenderana nemaharimita akadai souslet, solubility uye hydrophilicity. HPMCS yezvinhu zvakasiyana zvinogona kugadziridzwa zvinoenderana nezvinodiwa zvinodhaka.
HPMC uye HPMCs ine misiyano yakakosha mumakemikari chimiro, kuita uye nzvimbo dzekushandisa. HPMC iri ranyoreswa hydroxyprupropropyl methylcellose, iyo inoshandiswa zvakanyanya muminda yakawanda; Nepo Hpms iri sulfated kimcell®hpmc, iyo ine yepamusoro hydrofirity uye chaiyo kushanda, uye inonyanya kushandiswa muminda yehunyanzvi iyo inoda kusimba kwakanyanya, sekusunungurwa kwezvinodhaka.
Mukushandisa chaiko, sarudzo yeHpckana HPMCS inofanira kutsanangurwa maererano nezvinodiwa chaizvo uye zvinoshandiswa. Kana paine zvakakosha zvinodiwa kuti solubility, kugadzikana, etc., hpmc inogona kupihwa pekutanga. Kana pasina kunyanya zvakakwirira zvinodiwa nemutengo uye kuita, HPMC iine sarudzo yakajairika uye yehupfumi.
Kutumira Nguva: Jan-27-2025