Kugadzira carboxymethylcellulose (CMC) kunosanganisira akati wandei matanho uye kuita kwemakemikari. CMC ipolymer inonyungudika nemvura inotorwa kubva ku cellulose, polima yakasikwa inowanikwa mumadziro emiti. Inoshandiswa zvakanyanya mumaindasitiri akasiyana sechikafu, mishonga, zvizorwa, uye machira nekuda kwekukora, kudzikamisa, uye kusunga zvivakwa. Heino dhairekitori rakadzama rekugadzira carboxymethylcellulose:
Nhanganyaya yeCarboxymethylcellulose (CMC):
Carboxymethylcellulose (CMC) inotorwa kubva kune cellulose, inowanzoitika inowanzoitika polysaccharide inowanikwa muchirimwa sero madziro. Kugadzirwa kweCMC kunosanganisira kushandura cellulose kuburikidza nekuita kwemakemikari kuunza mapoka ecarboxymethyl kumusana we cellulose. Uku kugadziridzwa kunopa kunyungudika kwemvura uye zvimwe zvinodikanwa zvivakwa kune iyo polymer.
Raw Materials:
Cellulose: Yekutanga mbishi zvinhu zveCMC kugadzirwa ndeye cellulose. Cellulose inogona kutorwa kubva kwakasiyana siyana masosi akadai sehuni pulp, machira ekotoni, kana masara ekurima.
Sodium Hydroxide (NaOH): Iyo inozivikanwawo se caustic soda, sodium hydroxide inoshandiswa mumatanho ekutanga eCMC kugadzirwa kwe cellulose alkali kurapwa.
Chloroacetic Acid (ClCH2COOH): Chloroacetic acid ndiyo huru reagent inoshandiswa kuunza mapoka ecarboxymethyl kumusana we cellulose.
Etherification Catalyst: Macatalysts akadai sodium hydroxide kana sodium carbonate anoshandiswa kufambisa etherification reaction pakati pe cellulose uye chloroacetic acid.
Solvents: Solvents senge isopropanol kana ethanol inogona kushandiswa kunyungudutsa reactants uye rubatsiro mukuita maitiro.
Kugadzira Maitiro:
Kugadzirwa kwecarboxymethylcellulose kunosanganisira akati wandei matanho akakosha:
1. Alkali Kurapa Cellulose:
Cellulose inobatwa nealkali yakasimba, kazhinji sodium hydroxide (NaOH), kuti iwedzere reactivity yayo nekushandura mamwe emapoka ayo ehydroxyl kuita alkali cellulose. Kurapa uku kunowanzoitwa mumudziyo we reactor pane tembiricha yakakwira. Iyo alkali cellulose inoumbwa inobva yagezwa uye isina kugadzikana kubvisa yakawandisa alkali.
2. Etherification:
Mushure mekurapa alkali, cellulose inobatwa ne chloroacetic acid (ClCH2COOH) pamberi peiyo etherification catalyst. Izvi zvinounza mapoka ecarboxymethyl kumusana we cellulose, zvichikonzera kuumbwa kwecarboxymethylcellulose. Iyo etherification reaction inowanzoitika pasi pemamiriro ekudzora tembiricha, kudzvanywa, uye pH kuti uwane iyo inodiwa dhigirii yekutsiva (DS) uye huremu hwemamorekuru eCMC.
3. Kuwacha uye Kucheneswa:
Kutevera etherification reaction, iyo isina kuchena CMC chigadzirwa inoshambidzwa kuti ibvise isina kubatwa reagents, ne-zvigadzirwa, uye tsvina. Kugeza kunowanzoitwa uchishandisa mvura kana organic solvents inoteverwa nefiltration kana centrifugation. Matanho ekuchenesa anogonawo kusanganisira kurapwa nemaasidhi kana mabhesi ekugadzirisa pH uye kubvisa zvakasara zvinokonzeresa.
4. Kuomesa:
Iyo CMC yakacheneswa inozoomeswa kubvisa hunyoro uye kuwana chigadzirwa chekupedzisira muhupfu kana granular fomu. Kuomesa kunowanzoitwa uchishandisa nzira dzakaita sekupfapfaidza kuomeswa, vacuum kuomesa, kana kuomeswa nemhepo pasi pemamiriro akadzorwa kudzivirira kushatisa kana kuunganidzwa kwepolymer.
Kudzora Hunhu:
Matanho ekudzora emhando akakosha mukati meCMC yekugadzira maitiro kuti ive nechokwadi chekuenderana, kuchena, uye zvinodiwa zvechigadzirwa chekupedzisira. Key quality parameters dzinosanganisira:
Degree of substitution (DS): Avhareji nhamba yemapoka e-carboxymethyl paglucose unit mucheni ye cellulose.
Molecular weight distribution: Inotemerwa nemaitiro akadai seviscosity zviyero kana gel permeation chromatography (GPC).
Kuchena: Inoongororwa nenzira dzekuongorora dzakadai se infrared spectroscopy (IR) kana yepamusoro-performance liquid chromatography (HPLC) yekuona tsvina.
Viscosity: Chivakwa chakakosha kune akawanda maapplication, kuyerwa uchishandisa viscometers kuona kuenderana uye kuita.
Zvishandiso zveCarboxymethylcellulose:
Carboxymethylcellulose inowana kushandiswa kwakapararira mumaindasitiri akasiyana, kusanganisira:
Indasitiri Yezvekudya: Seyakakora, inosimbisa, uye emulsifier muzvigadzirwa zvakaita sesosi, madhirezi, ice cream, uye zvinhu zvakabikwa.
Pharmaceuticals: Mukugadzirwa kwemishonga sebhainda, disintegrant, uye viscosity modifier mumapiritsi, kumiswa, uye topical formulations.
Cosmetics: Muzvigadzirwa zvekuchengeta zvemunhu zvakaita semafuta ekuzora, mafuta ekuzora, uye mashamposi seanokora uye rheology modifier.
Micheka: Mukudhinda machira, saizi, uye kupedzisa maitiro ekuvandudza machira zvimiro uye kuita.
Zvakatipoteredza uye Chengetedzo Zvinotarisirwa:
Kugadzirwa kweCMC kunosanganisira kushandiswa kwemakemikari uye maitiro anonyanya kushandisa simba, izvo zvinogona kuve nemhedzisiro yezvakatipoteredza sekugadzira mvura yetsvina uye kushandiswa kwesimba. Kuedza kudzikisa kukanganisa kwezvakatipoteredza uye kuona kubata kwakachengeteka kwemakemikari zvinhu zvakakosha mukugadzira CMC. Kuitwa kweakanakisa maitiro ekurapa marara, kugona kwesimba, uye hutano hwepabasa nekuchengetedzeka kunogona kubatsira kudzikisira izvi zvinonetsa.
Kugadzirwa kwecarboxymethylcellulose kunosanganisira matanho akati wandei kutanga kubva pakutorwa kweselulosi kuenda kune alkali kurapwa, etherification, kucheneswa, uye kuomesa. Matanho ekudzora hunhu akakosha pakuona kuenderana uye kuchena kwechigadzirwa chekupedzisira, icho chinowana mashandisirwo akakura mumaindasitiri akasiyana. Mafungiro ezvakatipoteredza nekuchengetedza zvinhu zvakakosha zvekugadzirwa kweCMC, zvichisimbisa kukosha kwemaitiro akasimba uye ane mutoro ekugadzira.
Nguva yekutumira: Mar-27-2024