Fa'aaogāina ole CMC ile Fa'afomai
Carboxymethyl cellulose (CMC) o se vai-soluble polymer e maua mai le cellulose, lea e masani ona faʻaaogaina i le falemaʻi faʻafomaʻi ona o ona uiga faʻapitoa, e pei o le biocompatibility, non-toxicity, ma le lelei tele o le mucoadhesive. I lenei tusiga, o le a tatou talanoaina le tele o talosaga a CMC i vailaʻau.
- Ophthalmic applications: O le CMC e masani ona faʻaaogaina i sauniuniga o le mata, e pei o mata ma suauʻu, ona o lona gafatia e faʻateleina le taimi e nofo ai le vailaʻau i luga o le mata, ma faʻaleleia ai lona bioavailability. O le CMC foi e galue o se sui mafiafia ma tuʻuina atu le lubrication, faʻaitiitia le ita e mafua mai i le faʻaogaina o le vailaʻau.
- Fa'amālōlōina o manu'a: O vaila'au o lo'o fa'avae i le CMC ua fausia mo le fa'amaloloina o manu'a. O nei hydrogels e maualuga le vai ma maua ai se siosiomaga susu e faʻaleleia ai le faʻamalolo manuʻa. Ole CMC hydrogels e iai fo'i le biocompatibility sili ona lelei ma e mafai ona fa'aoga e fai ma fata mo le tuputupu a'e o sela ma masini.
- Tu'uina atu o vaila'au: O le CMC e fa'aaogaina lautele i faiga fa'apipi'i vaila'au, e pei o microspheres, nanoparticles, ma liposomes, ona o lona biocompatibility, biodegradability, ma mucoadhesive properties. E mafai ona fa'aleleia e le CMC le fa'aogaina o vaila'au, fa'aitiitia le o'ona, ma tu'uina atu fa'atatau ile ti'aga po'o totoga.
- Gastrointestinal applications: E faʻaaogaina le CMC i le faʻatulagaina o papa ma capsules e faʻaleleia ai a latou faʻamavae ma faʻaleagaina meatotino. O lo'o fa'aaogaina fo'i le CMC e fai ma mea fa'amau ma fa'ama'i i le fa'atupuina o laulau fa'ama'i tautala. O le CMC o loʻo faʻaaogaina i le faʻatulagaina o faʻamalologa ma emulsions e faʻaleleia ai lo latou mautu ma le viscosity.
- Talosaga nifo: O le CMC e faʻaaogaina i nifo nifo, e pei o le toothpaste ma le mouthwash, ona o lona gafatia e tuʻuina atu le viscosity ma faʻaleleia atili le tafe o mea o le faʻavae. E galue foi le CMC o se fusifusia, e taofia ai le vavaeeseina o vaega eseese o le faʻavae.
- Fa'aogaina o le toto: O le CMC e fa'aaogaina i fa'ama'i fa'ama'i, e pei o gels ma kulimi, ona o lona mucoadhesive meatotino. Ole fa'avae ole CMC e mafai ona fa'aleleia le taimi e nofo ai le vaila'au ile mucosa va'a, ma fa'aleleia atili ai lona bioavailability.
I le faaiuga, o le CMC o se polymer sili ona lelei ma le tele o faʻaoga i vailaʻau. O ona uiga tulaga ese, e pei o le biocompatibility, non-toxicity, ma le mucoadhesive gafatia, avea ma mea taua i sauniuniga ophthalmic, faʻamalolo manuʻa, faʻaogaina o vailaʻau, faʻaogaina o le manava, faʻasologa o nifo, ma sauniuniga vaʻaia. O le fa'aogaina o le fa'avae o le CMC e mafai ona fa'aleleia atili ai le bioavailability o vaila'au, fa'aitiitia o latou o'ona, ma tu'uina atu fa'atatau ile ti'eti'e po'o totoga fa'apitoa, ma fa'aleleia atili ai taunu'uga o tagata ma'i.
Taimi meli: Me-09-2023