Nibihe bintu byerekana imiterere ya sisitemu ya HPMC?

Hydroxypropyl methylcellulose (HPMC) ni polymer itandukanye ikoreshwa cyane nkibyimbye mu nganda zitandukanye nka farumasi, amavuta yo kwisiga, ibiryo, nibikoresho byubwubatsi. Gusobanukirwa imiterere yimiterere ya sisitemu ya HPMC ningirakamaro mugutezimbere imikorere yabo mubikorwa bitandukanye.

1. Viscosity:

Sisitemu ya HPMC yerekana imyitwarire yo kogosha, bivuze ko ububobere bwabo bugabanuka hamwe no kongera igipimo cyogosha. Uyu mutungo ufite akamaro mubisabwa aho bisabwa byoroshye cyangwa gutunganya, nko gusiga amarangi.

Ubwiza bwibisubizo bya HPMC buterwa nibintu nko kwibanda kuri polymer, uburemere bwa molekile, urugero rwo gusimbuza, ubushyuhe, nigipimo cyogosha.

Ku gipimo gito cyogosha, ibisubizo bya HPMC bitwara nkibisukari byamazi bifite ubukonje bwinshi, mugihe mugihe cyo hejuru cyogosha, bitwara nkamazi make atagaragara, byoroha gutemba byoroshye.

2. Thixotropy:

Thixotropy bivuga umutungo wamazi amwe kugirango agarure ububobere bwe uhagaze nyuma yo guhangayika. Sisitemu ya HPMC ikunze kwerekana imyitwarire ya thixotropic.

Iyo uhuye nikibazo cyo gukata, iminyururu miremire ya polymer ihuza icyerekezo cyogutemba, bikagabanya ubukonje. Iyo ihagaritse ryimyitozo ngororamubiri, iminyururu ya polymer isubira buhoro buhoro icyerekezo cyayo, bigatuma kwiyongera kwijimye.

Thixotropy irifuzwa mubisabwa nko gutwikira hamwe no gufatira hamwe, aho ibikoresho bikenera kubungabunga umutekano mugihe cyo kubisaba ariko bigatemba byoroshye munsi yintama.

3. Gutanga umusaruro:

Sisitemu ya HPMC yibyibushye akenshi ifite impungenge zumusaruro, aribwo guhangayikishwa byibuze bisabwa kugirango utangire gutemba. Munsi yiyi mihangayiko, ibikoresho bitwara nkibikomeye, byerekana imyitwarire yoroheje.

Guhangayikishwa n'umusaruro wibisubizo bya HPMC biterwa nibintu nka polymer yibanze, uburemere bwa molekile, nubushyuhe.

Guhangayikishwa no gutanga umusaruro ni ngombwa mubisabwa aho ibikoresho bigomba kuguma mu mwanya bitagendeye munsi yuburemere bwabyo, nko mu mpuzu zihagaritse cyangwa mu guhagarika ibice bikomeye mu marangi.

4. Ubushyuhe bukabije:

Ubukonje bwibisubizo bya HPMC buterwa nubushyuhe, hamwe n'ubukonje muri rusange bugabanuka uko ubushyuhe bwiyongera. Iyi myitwarire isanzwe ya polymer ibisubizo.

Ubushyuhe bukabije burashobora kugira ingaruka kumikorere no mubikorwa bya HPMC yibyibushye muri porogaramu zitandukanye, bisaba ko uhindurwa muburyo bwo gukora cyangwa ibipimo ngenderwaho kugirango ugumane ibintu byifuzwa mubushuhe butandukanye.

5. Kwishingira igipimo cyogosha:

Ubwiza bwibisubizo bya HPMC biterwa cyane nigipimo cyogosha, hamwe nigipimo kinini cyogosha kiganisha ku kugabanuka kwinshi bitewe no guhuza no kurambura iminyururu ya polymer.

Uku kugabanuka kwimyenda isobanurwa mubisanzwe nimbaraga-amategeko cyangwa moderi ya Herschel-Bulkley, ifitanye isano no guhangayikishwa no gukata no kugabanuka.

Gusobanukirwa nigipimo cyikigereranyo ningirakamaro muburyo bwo guhanura no kugenzura imyitwarire yimikorere ya HPMC yibyibushye mubikorwa bifatika.

6. Ingaruka zo Kwibanda:

Kongera imbaraga za HPMC mubisubizo mubisanzwe biganisha ku kwiyongera kwijimye no guhangayika. Ingaruka yo kwibandaho ningirakamaro kugirango ugere kumurongo wifuzwa no gukora mubikorwa bitandukanye.

Nyamara, murwego rwo hejuru cyane, ibisubizo bya HPMC birashobora kwerekana imyitwarire isa na gel, ikora imiterere y'urusobekerane rwongera cyane ubwiza no guhangayika.

7. Kuvanga no gutatanya:

Kuvanga neza no gukwirakwiza HPMC mubisubizo nibyingenzi kugirango ugere ku bwiza bumwe hamwe na rheologiya muri sisitemu.

Gutatana kutuzuye cyangwa guhuriza hamwe ibice bya HPMC birashobora kuganisha ku kwijimye kutameze kimwe no kubangamira imikorere mubisabwa nko gutwikira no gufatira.

Uburyo butandukanye bwo kuvanga hamwe ninyongeramusaruro birashobora gukoreshwa kugirango habeho gukwirakwiza neza no gukora sisitemu ya HPMC.

Imiterere ya rheologiya ya sisitemu ya HPMC yibyibushye, harimo viscosity, thixotropy, guhangayikishwa numusaruro, ubukonje bwubushyuhe, guterwa nigipimo cyogosha, ingaruka ziterwa, hamwe no kuvanga / gutatanya, bigira uruhare runini muguhitamo imikorere yabyo mubikorwa bitandukanye. Gusobanukirwa no kugenzura iyi mitungo nibyingenzi mugutegura ibicuruzwa bishingiye kuri HPMC hamwe nibyifuzo bihamye, bihamye, nibikorwa.