Hydroxypropyl methylcellulose (HPMC) ni selelose isanzwe ikomoka kuri selile ikoreshwa cyane muri farumasi, ubwubatsi, ibiryo nibindi bice.
(1) Ibiranga shingiro bya HPMC
HPMC ni ifu yera ishonga mumazi kugirango ibe igisubizo cyiza cya colloidal. Ifite neza, gutuza no kubyimba, kandi irashobora gukora firime iboneye. Ibiranga HPMC biterwa nurwego rwa methylation na hydroxypropylation, kuburyo hariho ibisobanuro bitandukanye nibikoreshwa.
(2) Ibyingenzi byingenzi bikoreshwa hamwe nikoreshwa rya HPMC
1. Inganda zimiti
a. Nkumuntu utwara ibiyobyabwenge kandi uhoraho-urekura
HPMC ikoreshwa kenshi nkumukozi uhoraho-urekura mugutegura ibiyobyabwenge. Muri tableti na capsules, HPMC irashobora gukora firime ihamye kandi ikagenzura igipimo cyo gusohora ibiyobyabwenge. Iyo ikoreshejwe, HPMC ivanze nibigize ibiyobyabwenge. Nyuma yo gufata ibinini cyangwa kuzuza capsule, HPMC irashobora kurekura buhoro buhoro imiti mu nzira ya gastrointestinal.
b. Nkumuhuza
Mu musaruro wa tablet, HPMC ikoreshwa kenshi nka binder. Iyo ivanze nibindi bikoresho, irashobora kunoza imbaraga nogukomera kwa tablet.
c. Nkumukozi uhagarika
Mu miti y’amazi, HPMC irashobora gukumira neza ibiyigize imiti gutuza, bityo bikagumana uburinganire bwibiyobyabwenge.
Inganda zubaka
a. Nkibyimbye kuri sima ya sima
Mu bwubatsi, HPMC ikoreshwa mu kuvanga sima, umucanga nibindi bikoresho kugirango hongerwe hamwe nubwubatsi bwa minisiteri. Irashobora kunoza uburyo bwo gufata amazi ya minisiteri kandi ikayirinda gukama vuba, bityo bikongera igihe cyakazi cya minisiteri.
b. Nkiyongera kuri tile yometse
HPMC irashobora gukoreshwa nk'inyongeramusaruro ya tile kugirango yongere ifatira hamwe nubwubatsi bwimikorere kandi irinde amatafari kugwa.
3. Inganda zibiribwa
a. Nkibyokurya byibyimbye hamwe na stabilisateur
HPMC ikoreshwa cyane mubyimbye mubiryo, nko muri jama, jellies n'ibinyobwa. Irashobora kongera ubwiza bwibicuruzwa no gukomeza umutekano wibicuruzwa.
b. Nka firime y'ibiryo mbere
HPMC irashobora gukoreshwa mugukora firime ipakira ibiryo kugirango ikore firime iboneye kurinda ibiryo.
4. Inganda zo kwisiga
a. Nkibyimbye byo kwisiga
HPMC isanzwe ikoreshwa mu kwisiga, nko koza mu maso, amavuta yo kwisiga, nibindi, nkibibyimbye kugirango bitezimbere imiterere nibicuruzwa.
b. Nka firime yahoze
HPMC irashobora gukora firime iboneye kandi ikoreshwa nka firime yahoze mubicuruzwa byita kuruhu, nka masike yo mumaso.
(3) Kwirinda gukoresha HPMC
Gukemura
Igipimo cyo gusesa cya HPMC giterwa nubushyuhe nibihe bikurura. Menya neza ko imvange ivanze neza mugihe cyo gusesa kugirango wirinde guhuriza hamwe.
Kugenzura ibitekerezo
Hindura kwibanda kuri HPMC ukurikije ibisabwa. Mu myiteguro ya farumasi, kwibanda cyane birashobora kugira ingaruka ku irekurwa ryibiyobyabwenge; mubikoresho byo kubaka, hasi cyane kwibandaho bishobora kuvamo imikorere idahagije.
Imiterere yo kubika
HPMC igomba kubikwa ahantu humye, hakonje, hirindwa ubushyuhe bwinshi nubushuhe kugirango bigumane ituze kandi neza.
Guhuza
Mugihe ushyira HPMC, guhuza kwayo nibindi bikoresho bigomba kwitabwaho, cyane cyane iyo bikoreshwa mubiyobyabwenge nibiribwa, kugirango harebwe ko nta ngaruka mbi zibaho.
HPMC ni selile itandukanye ikomoka hamwe na porogaramu zitandukanye. Kuva muri farumasi kugeza mubwubatsi, ibiryo kugeza kwisiga, imiterere yihariye ya HPMC ituma igira uruhare runini mubicuruzwa bitandukanye. Iyo uyikoresheje, birakenewe guhitamo ibisobanuro bikwiye hamwe nibitekerezo ukurikije ibisabwa byihariye, kandi ukitondera uburyo bwo kubikemura no kubika kugirango habeho gukora neza no guhagarara neza kubicuruzwa.
Igihe cyo kohereza: Kanama-09-2024