Hydroxypropyl methylcellulose (HPMC) ndi polima yosungunuka m'madzi yomwe imagwiritsidwa ntchito kwambiri muzamankhwala, chakudya, zomangira ndi zina. Chifukwa cha makulidwe ake abwino, kupanga mafilimu, emulsifying, kugwirizana ndi zinthu zina, amagwiritsidwa ntchito kwambiri ngati thickener, stabilizer ndi suspending agent. The rheological katundu wa HPMC, makamaka ntchito yake pa kutentha osiyana, ndi zinthu zofunika zimakhudza zotsatira zake ntchito.
1. Chidule cha HPMC Rheological Properties
Makhalidwe a Rheological ndi chiwonetsero chokwanira cha mapindikidwe ndi mawonekedwe otaya azinthu pansi pa mphamvu zakunja. Kwa zida za polima, kukhuthala ndi kumeta ubweya wa ubweya ndizozigawo ziwiri zodziwika bwino za rheological. The rheological zimatha HPMC makamaka amakhudzidwa ndi zinthu monga maselo kulemera, ndende, zosungunulira katundu ndi kutentha. Monga non-ionic cellulose ether, HPMC imasonyeza pseudoplasticity mu njira yamadzimadzi, ndiko kuti, kukhuthala kwake kumachepa ndi kuwonjezeka kwa shear.
2. Zotsatira za Kutentha pa HPMC Viscosity
Kutentha ndi chimodzi mwazinthu zazikulu zomwe zimakhudza rheological properties za HPMC. Pamene kutentha kumawonjezeka, kukhuthala kwa njira ya HPMC kumachepa. Izi zili choncho chifukwa kuwonjezeka kwa kutentha kumafooketsa mgwirizano wa hydrogen pakati pa mamolekyu amadzi, motero kuchepetsa mphamvu yolumikizirana pakati pa HPMC unyolo wa ma molekyulu, kupangitsa kuti maunyolo a maselo azikhala osavuta kusuntha ndi kuyenda. Chifukwa chake, pakutentha kwambiri, mayankho a HPMC amawonetsa kukhuthala kotsika.
Komabe, kusintha mamasukidwe akayendedwe a HPMC si ubale liniya. Kutentha kumakwera pang'onopang'ono, HPMC ikhoza kukhala ndi ndondomeko ya kusungunuka-mvula. Kwa HPMC, kugwirizana pakati pa kusungunuka ndi kutentha kumakhala kovuta kwambiri: mkati mwa kutentha kwina, HPMC idzathamanga kuchokera ku yankho, lomwe likuwonekera ngati kuwonjezeka kwakukulu kwa kukhuthala kwa yankho kapena mapangidwe a gel osakaniza. Chodabwitsa ichi nthawi zambiri chimachitika pamene chikuyandikira kapena kupitirira kutentha kwa kutentha kwa HPMC.
3. Mmene kutentha pa khalidwe rheological wa HPMC njira
Makhalidwe a rheological a yankho la HPMC nthawi zambiri amawonetsa kumeta ubweya wa ubweya, ndiko kuti, kukhuthala kumachepa pamene kumeta ubweya kumawonjezeka. Kusintha kwa kutentha kumakhudza kwambiri kumeta ubweya wa ubweya uku. Nthawi zambiri, kutentha kumawonjezeka, kukhuthala kwa njira ya HPMC kumachepa, ndipo kumeta ubweya wa ubweya kumawonekera kwambiri. Izi zikutanthauza kuti pa kutentha kwakukulu, kukhuthala kwa njira ya HPMC kumadalira kwambiri kumeta ubweya wa ubweya, mwachitsanzo, pa mlingo womwewo wa shear, njira ya HPMC pa kutentha kwakukulu imayenda mosavuta kusiyana ndi kutentha kochepa.
Kuonjezera apo, kuwonjezeka kwa kutentha kumakhudzanso thixotropy wa yankho la HPMC. Thixotropy amatanthauza katundu amene kukhuthala kwa njira yothetsera vutoli kumachepa pansi pa mphamvu yometa ubweya wa ubweya, ndipo mamasukidwe ake amatsitsimutsidwa pang'onopang'ono pambuyo pochotsa mphamvu yometa ubweya. Kawirikawiri, kuwonjezeka kwa kutentha kumabweretsa kuwonjezeka kwa thixotropy wa yankho la HPMC, mwachitsanzo, pambuyo pa kumeta ubweya wa ubweya kuchotsedwa, kukhuthala kumabwerera pang'onopang'ono kusiyana ndi kutentha kochepa.
4. Zotsatira za kutentha pa khalidwe la gelation la HPMC
HPMC ili ndi matenthedwe apadera a gelation katundu, mwachitsanzo, mutatha kutentha kutentha kwina (kutentha kwa gel osakaniza), yankho la HPMC lidzasintha kuchoka ku njira yothetsera kukhala gel. Njirayi imakhudzidwa kwambiri ndi kutentha. Kutentha kumachulukirachulukira, kuyanjana pakati pa hydroxypropyl ndi methyl m'malo mwa mamolekyu a HPMC kumawonjezeka, zomwe zimapangitsa kuti unyolo wa mamolekyu ukhale womangidwa, motero kupanga gel. Chodabwitsa ichi ndi chofunikira kwambiri m'mafakitale opanga mankhwala ndi zakudya chifukwa chingagwiritsidwe ntchito kusintha mawonekedwe ndi kutulutsa katundu.
5. Kugwiritsa ntchito ndi kufunikira kochita
Zotsatira za kutentha pa rheological properties za HPMC ndizofunika kwambiri pa ntchito zothandiza. Pakugwiritsa ntchito mayankho a HPMC, monga kukonzekera kumasulidwa kosalekeza, zonenepa chakudya, kapena zowongolera zomangira, zotsatira za kutentha kwa zinthu za rheological ziyenera kuganiziridwa kuti zitsimikizire kukhazikika ndi magwiridwe antchito a chinthucho pamikhalidwe yosiyanasiyana ya kutentha. Mwachitsanzo, pokonzekera mankhwala osamva kutentha, kusintha kwa kutentha kwa mamasukidwe akayendedwe ndi machitidwe a gelation a matrix a HPMC akuyenera kuganiziridwa kuti apititse patsogolo kuchuluka kwa mankhwalawo.
Kutentha kumakhudza kwambiri rheological properties za hydroxypropyl methylcellulose. Kuchuluka kutentha nthawi zambiri amachepetsa mamasukidwe akayendedwe a HPMC njira, timapitiriza ake kukameta ubweya-kupatulira kwenikweni ndi thixotropy, komanso akhoza kulimbikitsa matenthedwe gelation. Muzogwiritsa ntchito, kumvetsetsa ndikuwongolera momwe kutentha kumagwirira ntchito ku HPMC ndiye chinsinsi chothandizira kukhathamiritsa kwa magwiridwe antchito ndikuwongolera magawo.
Nthawi yotumiza: Sep-05-2024