Kedu ihe bụ CMC chịngọm?

Carboxymethyl cellulose (CMC), makwaara dị ka cellulose chịngọm, bụ ihe mgbakwunye na nke a na-ejikarị eme ihe na ụlọ ọrụ dị iche iche, gụnyere nri, ọgwụ, nlekọta onwe onye, ​​​​na ngwa mmepụta ihe. A na-enweta ya site na cellulose, polymer eke dị na osisi, site na usoro mgbanwe kemịkalụ. A na-eji CMC akpọrọ ihe maka ihe ndị pụrụ iche ya, nke gụnyere ịgba, nkwụsi ike, na ike imepụta ihe nkiri.

Nhazi na Njirimara:

A na-emepụta CMC site na imeghachi cellulose na chloroacetic acid na sodium hydroxide. Mgbanwe kemịkalụ a na-ebute iwebata otu carboxymethyl (-CH2-COOH) n'ime ọkpụkpụ azụ cellulose. Ogo nke nnọchi (DS), nke na-egosi nkezi ọnụọgụ nke otu carboxymethyl maka otu glucose, na-ekpebi njirimara nke ngwaahịa CMC.

CMC dị n'ọkwa dị iche iche dabere na viscosity ya, ogo nke nnọchi ya na nha nha. Akara ule DS dị elu na-egosipụta oke solubility na ike ịgbatị, ebe akara ule DS dị ala na-enye ndakọrịta ka mma na ihe mgbaze organic yana ihe ndị na-emepụta ihe nkiri ka mma.

Ngwa:

1. Ụlọ ọrụ nri: A na-ejikarị CMC eme ihe na ụlọ ọrụ nri dị ka ihe na-agbapụta, stabilizer, na emulsifier n'ọtụtụ ngwaahịa. Ọ na-eme ka udidi, viscosity, na mmetụta ọnụ na nhazi nri dị ka soseji, akwa akwa, ngwaahịa mmiri ara ehi, ngwaahịa esiri esi, na ihe ọṅụṅụ. CMC na-egbochikwa iguzobe kristal akpụrụ akpụ n'ime desserts oyi kpọnwụrụ ma na-akwalite nkwụsi ike shelf nke nri edoziri.

1. Pharmaceuticals: N'ime usoro ọgwụ, CMC na-eje ozi dị ka onye na-ekekọta, disintegrant, na viscosity modifier na mbadamba nkume, capsules, nkwusioru, na ointments. Ọ na-akwado mkpakọ mbadamba, na-akwalite mgbasa ọgwụ, ma na-enye otu n'ụdị usoro onunu ogwu. Nkwusioru dabere na CMC na-enye nkwụsi ike ka mma yana ịdị mfe nke nhazigharị maka ọgwụ ọnụ.
2. Ngwaahịa Nlekọta Onwe Onye: A na-ahụ CMC na nlekọta onwe onye dị iche iche na ngwaahịa ịchọ mma, gụnyere ncha eze, ncha ntutu, ude mmiri na ude. Ọ na-arụ ọrụ dị ka onye na-ebu ibu, onye na-akwụsịtụ, yana onye na-ejigide mmiri, na-eme ka udidi ngwaahịa, nkwụsi ike, na ịrụ ọrụ. Na ncha eze, CMC na-eme ka nkwụsi ike ma na-ahụ maka nkesa otu ihe na-arụ ọrụ.
3. Ngwa ụlọ ọrụ: A na-eji CMC n'ọtụtụ ngwa ụlọ ọrụ, dị ka ncha, akwa akwa, imepụta akwụkwọ, na igwu mmanụ. N'ime ihe nchacha, CMC na-arụ ọrụ dị ka onye na-egbochi ala na onye na-ewu viscosity, na-eme ka ịdị ọcha dị mma yana igbochi nrụgharị nke ala n'elu elu. N'ime akwa akwa, a na-etinye CMC dị ka onye na-eme ihe na-eme ka ọ dịkwuo elu iji kwalite ike ákwà na nbipụta.
4. Ụlọ ọrụ mmanụ na gas: A na-eji CMC na-egwupụta mmiri dị ka viscosifier na onye na-ahụ maka nkwụsị mmiri. Ọ na-enyere aka ịnọgide na-enwe viscosity na nkwụsi ike na-egwupụta apịtị, na-ebelata esemokwu ma na-eme ka mmanye mmanu na-eme ka ọ dịkwuo mma n'oge a na-egwupụta ihe. CMC na-egbochikwa mfu mmiri n'ime nhazi nke nwere ike imegharị ya, na-eme ka iguzosi ike n'ezi ihe na nrụpụta nke ọma.

Njirimara na uru ndị isi:

• Thickening: CMC na-egosipụta ihe ndị na-eme ka ọ dị oke mma, na-emepụta ngwọta viscous na obere mkpokọta. Ọ na-eme ka ọdịdị ahụ dịkwuo mma na nkwụsi ike nke ngwaahịa, na-eme ka njirimara na arụmọrụ ha dịkwuo mma.
• Nkwụsi ike: CMC na-arụ ọrụ dị ka ihe nkwụsi ike, na-egbochi nkewa nke oge na ịnọgide na-enwe nkesa otu ihe na nhazi. Ọ na-eme ka ndụ nchekwa ngwaahịa dịkwuo elu ma gbochie syneresis na gels na emulsions.
• Mmiri Solubility: CMC bụ nke ukwuu soluble na mmiri, akpụ doro anya, uzo ngwọta. Ya ngwa ngwa hydration na dispersibility na-eme ka ọ dị mfe itinye n'ime aqueous formulations, na-enye edo viscosity na udidi.
• Ịme ihe nkiri: CMC nwere ike ịmepụta ihe nkiri na-agbanwe agbanwe na nke jikọtara ọnụ mgbe akpọnwụwo, na-enye ihe mgbochi na njigide mmiri. A na-eji ya na mkpuchi, nrapado, na ihe nkiri a na-eri nri iji meziwanye ike, ntanye, na iguzosi ike n'ezi ihe nkiri.
• Biocompatibility: A na-amatakarị CMC dị ka nchekwa (GRAS) site n'aka ndị ọchịchị na-achịkwa ma na-ejikarị ya na nri, ọgwụ na ngwaahịa nlekọta onwe onye. Ọ naghị egbu egbu, enweghị mgbakasị ahụ, na biodegradable, na-eme ka ọ dị mma maka ngwa dị iche iche.

Atụmatụ usoro iwu:

Ndị isi nri na ọgwụ na-achịkwa CMC n'ụwa niile, gụnyere United States Food and Drug Administration (FDA), European Safety Authority (EFSA), na Kọmitii Ọkachamara FAO/WHO na mgbakwunye nri (JECFA). A kwadoro ya maka iji ya dị ka ihe mgbakwunye nri, ihe mgbakwunye ọgwụ, na ihe ịchọ mma n'ime oke akọwapụtara.

Ụlọ ọrụ na-achịkwa na-ewepụta njirisi ịdị ọcha, ọkwa kacha ojiji, yana nkọwapụta maka ngwaahịa CMC iji hụ na nchekwa na ịdị mma ha. Irube isi n'iwu ndị a dị mkpa maka ndị na-emepụta ahịa ịre ngwaahịa nwere CMC n'ụzọ iwu kwadoro.

Ihe ịma aka na oke:

Ọ bụ ezie na CMC na-enye ọtụtụ uru, ọ na-ewetakwa ụfọdụ ihe ịma aka na njedebe:

• PH Sensitivity: CMC nwere ike ịnweta pH dabere solubility na viscosity mgbanwe, na-emetụta arụmọrụ ya na usoro dị iche iche. Enwere ike ịchọ mmezi na pH iji kwalite ọrụ ya na ngwa a kapịrị ọnụ.
• Mmetụta Shear: Ngwọta CMC na-eme ka shear-thinning, nke pụtara viscosity ha na-ebelata n'okpuru nrụgide shiee. Ekwesịrị ịtụle omume rheological a n'oge nhazi na njikwa iji nweta nkwekọ ngwaahịa achọrọ.
• Okwu ndakọrịta: CMC nwere ike iji ụfọdụ ihe ma ọ bụ mgbakwunye na-emekọrịta ihe na nhazi, na-ebute mmetụta na-adịghị mma dị ka mbelata viscosity ma ọ bụ enweghị ntụkwasị obi. Nnwale ndakọrịta dị mkpa iji hụ na ndakọrịta na ebuli arụmọrụ nhazi.
• Ọdịdị Hygroscopic: CMC nwere akụrụngwa hygroscopic, na-amịkọrọ mmiri sitere na gburugburu ebe obibi. Nke a nwere ike imetụta nkwụsi ike na ihe nrịbama nke usoro ntụ ntụ ma nwee ike ịchọ nkwakọ ngwaahịa na ọnọdụ nchekwa kwesịrị ekwesị.

Echiche Ọdịnihu:

Ka ụlọ ọrụ na-aga n'ihu na-ebute nkwado, nchekwa, na ịrụ ọrụ, a na-atụ anya na ọchịchọ CMC ga-eto. Nchọpụta na-aga n'ihu na-achọ ịmepụta ihe nrụpụta CMC gbanwetụrụ nwere ihe ndị nwere nkwalite maka ngwa ụfọdụ, yana usoro mmepụta gburugburu ebe obibi iji belata mmetụta gburugburu ebe obibi.

Ọganihu na teknụzụ nhazi na usoro nhazi nwere ike gbasaa ịba uru na ntụgharị nke CMC na ụlọ ọrụ dị iche iche. Na mgbakwunye, ụlọ ọrụ na-ahụ maka njikwa ga-aga n'ihu na-enyocha ma nyochaa nchekwa na nrụpụta ngwaahịa nwere CMC iji hụ na nchekwa ndị ahịa na nnabata na ụkpụrụ iwu.

carboxymethyl cellulose (CMC) bụ ihe mgbakwunye bara uru nke nwere ngwa dị iche iche n'ofe ọtụtụ ụlọ ọrụ. Ngwongwo ya pụrụ iche, gụnyere ịgba, nkwụsi ike, na ike imepụta ihe nkiri, na-eme ka ọ dị mkpa na nri, ọgwụ, nlekọta onwe onye, ​​na usoro mmepụta ihe. N'agbanyeghị ihe ịma aka na njedebe, nchọpụta na-aga n'ihu na nkwa ọhụrụ na-ekwe nkwa ịkwalite ọganihu na nkà na ụzụ CMC, na-egbo mkpa na-agbanwe agbanwe nke ndị na-azụ ahịa na ụlọ ọrụ n'ụwa nile.