Hydroxypropylmethylcellulose (HPMC) bụ polymer soluble mmiri nke sitere na cellulose eke na-ejikarị eme ihe n'ọtụtụ ụlọ ọrụ n'ihi ikike ya ịmepụta viscosities dị iche iche na ngwọta mmiri. HPMC nwere ngwa dị iche iche na ụlọ ọrụ ọgwụ, nri na ịchọ mma. Viscosity bụ isi njirimara nke ngwọta HPMC na-emetụta arụmọrụ ha na ngwa ndị a.
Ihe na-emetụta viscosity:
1. Ntụkwasị obi: Ntinye uche nke HPMC na ngwọta na-emetụta kpọmkwem viscosity nke ngwọta. Ka ntinye uche HPMC na-abawanye, viscosity nke ngwọta na-abawanye ka ụdọ polymer na-agbanyekwu. Otú ọ dị, oke ntinye uche nwere ike ime ka ngwọta siri ike na gel dị ka nke nwere ike bụrụ ihe na-adịghị mma maka ụfọdụ ngwa.
2. Ihe dị arọ molecular: The molecular arọ nke HPMC bụ isi ihe na-emetụta viscosity nke ngwọta. Ka molekụla arọ nke HPMC na-abawanye, viscosity nke ngwọta na-abawanye n'ihi ụbara njikọ nke ụdọ polymer. HPMC nwere ibu molekụla dị elu nwere agbụ ogologo ogologo, na-ebute ngwọta viscous karịa.
3. Okpomọkụ: The viscosity nke HPMC ngwọta na-emetụtakwa okpomọkụ. Ka okpomọkụ nke ngwọta na-abawanye, viscosity nke ngwọta na-ebelata. Mbelata nke viscosity bụ n'ihi mbelata nke ike intermolecular n'etiti ụdọ polymer, na-ebute obere njikọ na mmụba mmiri.
4. Uru pH: Uru pH nke ngwọta ga-emetụtakwa viscosity nke ngwọta HPMC. Ụkpụrụ pH na-abụghị oke 5.5-8 nwere ike ime ka mbelata na viscosity n'ihi mgbanwe na solubility na ụgwọ nke HPMC polymer.
5. Salinity: Salinity ma ọ bụ ike ionic nke ngwọta na-emetụtakwa viscosity nke ngwọta HPMC. Ịba ụba nke nnu na-egbochi mmekọrịta HPMC polymer chain, na-ebute mbelata na viscosity ngwọta.
6. Ọnọdụ Shear: Ọnọdụ ịkpụ nke ekpughere ihe ngwọta HPMC ga-emetụtakwa viscosity nke ngwọta. Ọnọdụ shear nwere ike ime ka mbelata nwa oge na viscosity, dị ka mgbe ị na-agwakọta ma ọ bụ na-agbapụta ihe ngwọta. Ozugbo e wepụrụ ọnọdụ shear, viscosity na-alaghachi ngwa ngwa na ọnọdụ kwụ ọtọ.
na ngwụcha:
A na-emetụta viscosity nke ngwọta mmiri HPMC site n'ọtụtụ ihe dị mkpa ka a tụlee mgbe ị na-emepụta ngwaahịa ahụ. Ntinye uche, ịdị arọ molekụla, okpomọkụ, pH, salinity, na ọnọdụ shear bụ ihe kachasị mkpa na-emetụta viscosity nke ngwọta HPMC. Ịghọta ihe ndị a nwere ike inyere ndị nrụpụta aka ịkwalite viscosity nke ngwọta HPMC maka ngwa ụfọdụ. Viscosity bụ njirimara dị mkpa nke ngwọta HPMC dịka ọ nwere ike ikpebi arụmọrụ na nkwụsi ike nke ngwaahịa ndị dabeere na HPMC.
Oge nzipu: Ọktoba 16-2023