Hydroxypropylmethylcellulose (HPMC) bụ polymer na-ewu ewu nke a na-eji na ụlọ ọrụ dịka ọgwụ, ihe owuwu, nri na nlekọta onwe onye. Ọ bụ ụdị cellulose gbanwetụrụ site na iji propylene oxide meghachi omume methylcellulose. HPMC bụ ọcha ma ọ bụ na-acha ọcha, enweghị isi, ntụ ntụ na-enweghị ụtọ, na-agbaze ngwa ngwa na mmiri, ethanol na ihe mgbaze ndị ọzọ. Akwụkwọ a na-atụle isi teknuzu egosi HPMC.
viscosity
Viscosity bụ ndepụta teknụzụ kachasị mkpa nke HPMC, nke na-ekpebi omume na ngwa ya na ụlọ ọrụ dị iche iche. HPMC nwere viscosity dị elu, nke pụtara na o nwere udidi dị ka mmanụ aṅụ. Enwere ike gbanwee viscosity nke HPMC site na ịgbanwe ogo nnọchi nke otu hydroxyl. Ka ogo nke nnọchi anya dị elu, ka viscosity dị elu.
Ogo nke nnọchi
Ogo nke nnọchi (DS) bụ ihe ngosi teknụzụ ọzọ dị mkpa nke HPMC, nke na-ezo aka na ọnụ ọgụgụ nke otu hydroxyl ndị otu hydroxypropyl na otu methyl nọchiri anya. DS nke HPMC na-adịkarị site na 0.1 ruo 1.7, yana DS dị elu na-egosi mgbanwe dị ukwuu. DS nke HPMC na-emetụta solubility, viscosity na gel Njirimara.
molekụla arọ
The molekụla arọ nke HPMC bụkwa ihe dị mkpa teknuzu index na-emetụta ya anụ ahụ na kemịkal Njirimara dị ka solubility, viscosity, na gelation. HPMC na-enwekarị ịdị arọ molekụla nke 10,000 ruo 1,000,000 Daltons, yana ịdị arọ molekụla dị elu na-egosi ụdọ polymer ogologo. The molekụla arọ nke HPMC na-emetụta ya ndim arụmọrụ, film akpụ ike na mmiri na-ejide ikike.
PH uru
Uru pH nke HPMC bụ ndepụta ọrụ teknụzụ dị mkpa na-emetụta solubility na viscosity ya. HPMC bụ soluble na acidic na alkaline ngwọta, ma viscosity ya elu n'okpuru ọnọdụ acidic. Enwere ike ịhazi pH nke HPMC site na ịgbakwunye acid ma ọ bụ ntọala. HPMC na-enwekarị pH n'etiti 4 na 9.
mmiri ọdịnaya
Ọdịnaya dị n'ime mmiri nke HPMC bụ ndenye teknụzụ dị mkpa nke na-emetụta nkwụsi ike nchekwa ya na arụmọrụ nhazi ya. HPMC bụ hygroscopic, nke pụtara na ọ na-amịkọrọ mmiri sitere na ikuku. Ekwesịrị idowe ọdịnaya mmiri nke HPMC n'okpuru 7% iji hụ na nkwụsi ike na ịdị mma ya. Ọdịnaya dị elu nke mmiri nwere ike iduga caking polymer, mkpọkọ na mmebi.
ntụ ọdịnaya
Ọdịnaya ash nke HPMC bụ ihe ntinye aka dị mkpa na-emetụta ịdị ọcha na ịdịmma ya. Ash na-ezo aka n'ụfọdụ inorganic fọdụrụ ka agbachara HPMC ọkụ. Ọdịnaya ntụ nke HPMC kwesịrị ịbụ ihe na-erughị 7% iji hụ na ịdị ọcha na ịdị mma ya. Ọdịnaya ntu dị elu nwere ike igosi ọnụnọ adịghị ọcha ma ọ bụ mmetọ na polymer.
Gelation okpomọkụ
The gel okpomọkụ nke HPMC bụ ihe dị mkpa teknuzu index na-emetụta ya jel arụmọrụ. HPMC nwere ike gel n'okpuru ụfọdụ ọnọdụ okpomọkụ na itinye uche. Enwere ike imezi okpomọkụ gelation nke HPMC site n'ịgbanwe ogo nke nnọchi na ịdị arọ molekụla. Okpomọkụ gelling nke HPMC na-abụkarị 50 ruo 90 Celsius.
na ngwụcha
Hydroxypropylmethylcellulose (HPMC) bụ polymer multifunctional nwere ọtụtụ nkọwa. The isi oru egosi nke HPMC na-agụnye viscosity, ogo nnọchi, molekụla arọ, pH uru, mmiri ọdịnaya, ash ọdịnaya, gelation okpomọkụ, wdg Ndị a oru egosi emetụta anụ ahụ na chemical Njirimara nke HPMC na-ekpebi ya arụmọrụ dị iche iche industries. Site n'ịmara nkọwa ndị a, anyị nwere ike ịhọrọ ụdị HPMC ziri ezi maka ngwa anyị akọwapụtara ma hụ na ọ dị mma na nkwụsi ike.
Oge nzipu: Sep-04-2023