1. Nwere òkè sel
Ihe eji eme iheHpmcbụ sellosuse sitere na osisi pulp ma ọ bụ nke ahịhịa ma ọ bụ plalp. Akụkụ ahịhịa ndị a sitere n'okike nwere nnukwu ọnụọgụ β-glucose nke nkeji ma ọ bụ isi ihe ndabere maka mmepụta HPMC. A na-ejikarị ya ọcha dị elu na-abụkarị ihe na mmepụta nke hpmc dị elu n'ihi ọdịnaya adịghị ọcha ya.
2.
Achọrọ sodium hydroxide (NaOh) ka achọrọ maka ọdịnihu na alkalization nke cellose. Ọrụ ya bụ isi gụnyere:
Molecus cellulose na mmeghachi omume na-abawanye;
Ibibi mpaghara kristal nke cellulose iji mee ka ọ dị mfe ịnweta mmeghachi omume gị;
Na-akwalite mmeghachi omume na-esote na mmeghachi omume hydroxypropyylopo.
3 .thyl chloride (ch₃cl)
Methyl chloride (methych chloride) bụ ihe dị mkpa maka mmeghachi omume methylation na memacell®. Ọ na-emeghachi omume na cellulose iji dochie otu Hydroxy Hydroxy na Methoxy Otu (-OC) iji mepụtaMethyl Cellulose (Mc), - bido imezi sọlị na akụrụngwa anụ ahụ na kemịkal nke cellulose.
4. Proplene oxide (c₃h₆o)
A na-ejikarịxide propylene na mmeghachi omume HydroxyPropy, nke nwere ike iwebata hydropyyl (-chchohyl (-chchohchy di iche iche. Okwu mmeghe nke hydroxypyl nwere ike:
Ọzọkwa kwalite mmiri nke HPMC;
Meziwanye viscosity Njirimara nke ihe ngwọta ya;
Meziwanye nkwụsi ike na ọnọdụ dị iche iche.
5
A na-eji mmiri ma ọ bụ ihe mgbaze (dị ka ISoPopananol, methanol, wdg) dị ka mmeghachi omume na-eme ka agwakọta edo na njikwa mmeghachi omume. Na mgbakwunye, a na-eji ụfọdụ solvents iji wepu ihe ndị na-agụta na nnweta na usoro ịsa ahụ iji hụ na ịdị ọcha nke ngwaahịa a.
6. Acidic ma ọ bụ alkaline
Iji bulie ọnọdụ mmeghachi omume ma melite arụmọrụ nke ogo, acidic ma ọ bụ alkaline ma ọ bụ usoro mmepụta iji dozie uru PH dị ka nke a ga-enwe ike ịga n'ihu n'ọnọdụ dị mma.
7. Ihe ndị ọzọ aexiliary
Enwere ike iji ya na-akwụsi ike, enwere ike iji ndị na-egbochi ihe na-egbochi ya na usoro mmepụta ọzọ iji meziwanye ụdị HPMC, welie nguzosi ike ya, ma jikwa ihe mkpuchi ya na kemịkalụ ya.
Kimacell®hpmc na-emepụta site na alkalization, methethy na hydroxypyyylation ekewasị.Ihe eji eme ya bu:
Oke cellulose (tumadi site na osisi pulp ma ọ bụ akwa a nụchara)
Sodium hydroxide (NaOh) (maka alkalization)
Methyl chloride (ch₃cl) (maka methylition)
Proplene oxide (c₃h₆o) (maka hydroxylipyyyyyy)
Mmiri ma ọ bụ ihe mgbaze (maka mmeghachi omume na ịsacha)
Ndị na-ahụkarị (maka mmeghachi omume)
A na-eji HPMC mee ihe n'ọtụtụ ụlọ ọrụ dịka ọgwụ, ihe owuwu, ihe oriri, nri, na ikike dị mma, ike mgbanwe na ikike mgbanwe na biocompatisibility.
Oge post: Feb-11-2025