Hydroxypropyl methylcellulose bụ ihe dị ịrịba ama nonionic agwakọta ether nke cellulose nke gbanweela ụlọ ọrụ kemịkalụ. A na-emepụta polymer site n'ịgbanwe cellulose eke sitere na osisi ma ọ bụ owu. A na-eji HPMC eme ihe n'ụzọ dị iche iche n'ihi ihe ndị magburu onwe ya gụnyere ịgba, nkwụsịtụ, emulsifying, mmanụ mmanu na njide mmiri.
Na mgbakwunye, HPMC nwere njikwa mara mma na mwepụta nke ihe ndị na-arụ ọrụ na usoro ọgwụ dị iche iche, gụnyere mbadamba, capsules, ointments, na gels. Site na ịdị ọcha ya dị elu yana ezigbo bioacompatibility, HPMC na-ezute ụkpụrụ ọgwụ kachasị elu, na-emeziwanye ogo na nrụpụta ọgwụ.
Ọdịdị na-abụghị ionic nke HPMC na-eme ka ọ bụrụ nhọrọ magburu onwe ya maka ụlọ ọrụ dịgasị iche iche gụnyere nri, ihe ịchọ mma na ihe owuwu. Dị ka a nri mgbakwunye thickener, HPMC nwere ike imeziwanye udidi na nkwụsi ike nke esichara nri, mgbe na ịchọ mma ụlọ ọrụ, ọ na-arụ ọrụ dị mkpa dị ka ihe nkedo, emulsifier na thickener. Na-ewu ụlọ, HPMC nwere ike iji dị ka ihe na-ejigide mmiri, gluu na thickener iji melite adhesion, anwụ ngwa ngwa na ike nke ihe ụlọ.
Arụ ọrụ kacha mma nke HPMC sitere na ntinye nke hydroxypropyl na otu methyl na ọkpụkpụ cellulose. Ndị otu Hydroxypropyl (HP) na-ahụ maka ịba ụba solubility, ebe otu methyl na-ebelata njikọkọ hydrogen ma kwalite solubility mmiri. Ogo nke nnọchi nke otu HP na methyl na HPMC dị oke mkpa n'ịchọpụta akụrụngwa ya, gụnyere viscosity na solubility.
HPMC bụ akụkụ dị mkpa nke sistemụ nnyefe ọgwụ na-achịkwa. N'ime usoro ndị a, HPMC na-ebuli ntọhapụ ọgwụ n'ụzọ a na-achịkwa, na-ahụ na ọ dị mma ọgwụgwọ ọgwụgwọ, ịba ụba bioavailability na mbelata mmetụta. A pụkwara ịmepụta polymer n'ime mbadamba ihe matriks, nke nwere ihe ndị na-ahapụ ya, na-ekwe ka a na-ahapụ ọgwụ ahụ n'ime ahụ ruo ogologo oge.
Otu n'ime isi uru nke HPMC bụ biocompatibility ya. Ihe onwunwe a na-eme ka ọ baa uru na usoro ọgwụ maka nchịkwa ọnụ n'ihi na ọ dị mma, adịghị egbu egbu na nke na-adịghị emeghachi omume na anụ ahụ. Tụkwasị na nke ahụ, HPMC nwere ihe ndị na-emepụta ihe nkiri dị mma ma dị mma maka mkpuchi nke mbadamba nkume, capsules na granules.
HPMC bụ polymer multifunctional pụrụ iche nke enwere ike iji na ngwa dị iche iche gụnyere ọgwụ, ihe ịchọ mma, nri na ihe owuwu. Ngwongwo ya pụrụ iche, gụnyere ịgba, nkwụsịtụ na njide mmiri, na-eme ka ọ bụrụ otu n'ime ihe ndị kachasị mkpa na usoro ọgbara ọhụrụ. Site na ntọhapụ ha dị oke mma, ndakọrịta, yana ikike ntọhapụ a na-achịkwa, HPMC agbanweela ụlọ ọrụ nnyefe ọgwụ, na-eme ka nrụpụta ọgwụ, nchekwa na ịdị mma dịkwuo mma. Obi abụọ adịghị ya na HPMC ga-anọgide na-arụ ọrụ dị mkpa na ụlọ ọrụ kemịkalụ.
Oge nzipu: Sep-08-2023