He aha ka Hydroxypropyl Methylcellulose i hana ʻia mai

ʻO ka Hydroxypropyl methylcellulose (HPMC) he polymer semisynthetic i hoʻohana ʻia i nā ʻano ʻoihana like ʻole, me ke kūkulu ʻana, nā meaʻai, nā lāʻau lapaʻau, a me nā huahana mālama pilikino. He mea waiwai ia no kona hiki ke hoʻomaikaʻi i nā waiwai rheological o nā formulations, a me kona kūlike me nā mea ʻē aʻe a me kona haʻahaʻa haʻahaʻa. No ka hoʻomaopopo ʻana i ka hana ʻana o HPMC, pono e hoʻomaopopo mua i ke ʻano a me nā waiwai o cellulose.

ʻO ka Cellulose kahi kaulahao lōʻihi o nā molekole glucose i loaʻa i loko o nā paia o nā mea kanu. Hoʻopili pū ʻia nā molekala glucose e nā paʻa beta-1,4-glycosidic, e hana ana i kahi kaulahao laina. Hoʻopaʻa ʻia nā kaulahao e nā paʻa hydrogen a me nā pūʻali Van der Waals e hana i nā hale paʻa a paʻa. ʻO ka cellulose ka mea nui loa o nā mea ola ma ka honua, a hoʻohana ʻia ia i nā ʻano hana like ʻole, me ka pepa, nā textiles, a me nā mea kūkulu hale.

ʻOiai he nui nā waiwai pono o ka cellulose, he ʻoʻoleʻa loa ia a hiki ʻole ke hoʻohana ʻia i nā ʻano hana. No ka lanakila ʻana i kēia mau palena, ua hoʻomohala ka poʻe ʻepekema i ka nui o nā derivatives cellulose i hoʻololi ʻia, me HPMC. Hana ʻia ka HPMC ma o ka hoʻololi ʻana i ka cellulose kūlohelohe ma o ke ʻano o nā hopena kemika.

ʻO ka hana mua i ka hana ʻana i ka HPMC ʻo ka loaʻa ʻana o ka mea hoʻomaka cellulose. Hiki ke hana i kēia ma ka unuhi ʻana i ka cellulose mai nā kumu mea kanu e like me ka pulp lāʻau, pulupulu, a i ʻole ka ʻohe. A laila mālama ʻia ka cellulose me kahi solution alkaline, e like me ka sodium hydroxide a i ʻole potassium hydroxide, e hoʻoneʻe i nā haumia a wāwahi i nā fiber cellulose i loko o nā ʻāpana liʻiliʻi. Ua ʻike ʻia kēia kaʻina hana ʻo mercerization, a ʻoi aku ka maʻalahi o ka cellulose e hoʻololi.

Ma hope o ka mercerization, hoʻopili ʻia ka cellulose me ka hui ʻana o ka propylene oxide a me ka methyl chloride e hoʻokomo i nā pūʻulu hydroxypropyl a me methyl ma luna o ka iwi kuamoʻo cellulose. Hoʻohui ʻia nā hui hydroxypropyl e hoʻomaikaʻi i ka solubility a me ka mālama ʻana i ka wai o ka cellulose, aʻo nā hui methyl e hoʻonui i ka paʻa a hoʻemi i ka reactivity o ka cellulose. Hana ʻia ka pane ma ke alo o kahi catalyst, e like me ka sodium hydroxide a i ʻole potassium hydroxide, a ma lalo o nā kūlana hoʻomalu o ka mahana, kaomi, a me ka manawa pane.

ʻO ke degere o ka hoʻololi ʻana (DS) o HPMC e pili ana i ka helu o nā pūʻulu hydroxypropyl a me methyl i hoʻokomo ʻia ma luna o ka iwi kuamoʻo cellulose. Hiki ke ʻokoʻa ka DS ma muli o nā waiwai i makemake ʻia o ka HPMC a me ka noi kikoʻī e hoʻohana ʻia nei. ʻO ka maʻamau, ʻoi aku ka nui o nā waiwai DS i ka HPMC me ka haʻahaʻa haʻahaʻa a me ka wikiwiki o ka hoʻoheheʻe ʻana, ʻoiai ʻo nā koina DS haʻahaʻa e loaʻa i ka HPMC me ka viscosity kiʻekiʻe a me ka lohi o ka dissolution rate.

Ma hope o ka pau ʻana o ka hopena, hoʻomaʻemaʻe ʻia ka huahana a maloʻo e hana i ka pauka HPMC. ʻO ke kaʻina hana hoʻomaʻemaʻe e pili ana i ka wehe ʻana i nā kemika i hana ʻole ʻia, nā koena solvents, a me nā haumia ʻē aʻe mai ka HPMC. Hana ʻia kēia ma o ka hui ʻana o ka holoi ʻana, kānana, a me ka hoʻomaloʻo ʻana.

ʻO ka huahana hope he pauka keʻokeʻo a keʻokeʻo ʻaʻole ʻono a ʻono ʻole. Hiki ke hoʻoheheʻe ʻia ka HPMC i ka wai a me nā mea hoʻoheheʻe kūlohelohe, a hiki ke hana i nā gels, nā kiʻiʻoniʻoni, a me nā hale ʻē aʻe e pili ana i nā kūlana o ka hoʻohana ʻana. He polymer non-ionic ia, ʻo ia hoʻi, ʻaʻole ia e lawe i ka uku uila, a ua manaʻo ʻia ʻaʻole ia he mea ʻawaʻawa a palekana no ka hoʻohana ʻana i nā ʻano noi.

Hoʻohana ʻia ka HPMC i nā ʻano hana like ʻole, me nā pena, nā mea hoʻopili, nā mea hoʻopaʻa, nā lāʻau lapaʻau, a me nā huahana meaʻai. Ma nā hana kūkulu, hoʻohana pinepine ʻia ka HPMC ma ke ʻano he mānoanoa, binder, a me nā kiʻiʻoniʻoni mua i nā huahana cementitious a me gypsum-based, e like me nā mortars, grouts, a me nā pūhui hui.