ʻO ke ʻano hana hoʻomohala alkaline kahi ala maʻamau no ka hana ʻana i ka hydroxypropyl methyl cellulose (HPMC). Hoʻopili kēia ʻano hana i ka hopena o ka cellulose me ka sodium hydroxide (NaOH) a laila me ka propylene oxide (PO) a me ka methyl chloride (MC) ma lalo o kekahi mau kūlana.
ʻO ke ʻano o ka hoʻoheheʻe ʻana i ka alkaline ka pono o ka hana ʻana i ka HPMC me kahi kiʻekiʻe o ka hoʻololi ʻana (DS), ka mea e hoʻoholo ai i kāna mau waiwai e like me ka solubility, viscosity, a me ka gelation. ʻO ke ala e pili ana i kēia mau ʻanuʻu:
- Hoʻomākaukau i ka Cellulose
Loaʻa ka cellulose mai nā kumu kūlohelohe e like me ka lāʻau, ka pulupulu, a i ʻole nā mea kanu ʻē aʻe. Hoʻomaʻemaʻe muaʻia ka cellulose a laila mālamaʻia me ka NaOH e hana i ka sodium cellulose, he mea koʻikoʻi ia i ka hanaʻana o HPMC.
- Pane o ka Sodium Cellulose me ka Propylene Oxide (PO)
Hoʻopili ʻia ka sodium cellulose me PO ma ke alo o kahi catalyst e like me ka tetramethylammonium hydroxide (TMAH) a i ʻole ka sodium hydroxide (NaOH) ma nā wela kiʻekiʻe a me nā kaomi. ʻO ka hopena ka hopena i ka hana ʻana o ka hydroxypropyl cellulose (HPC).
- Pane o HPC me Methyl Chloride (MC)
Hoʻopili ʻia ka HPC me MC i mua o kahi mea hoʻoheheʻe e like me ka sodium hydroxide (NaOH) a i ʻole hydrochloric acid (HCl). ʻO ka hopena ka hopena i ka hoʻokumu ʻana o ka hydroxypropyl methyl cellulose (HPMC).
- Holoi a hoʻomaloʻo
Ma hope o ka hopena, holoi ʻia ka huahana me ka wai a maloʻo no ka loaʻa ʻana o ka HPMC. Hoʻomaʻemaʻe pinepine ʻia ka huahana me ka hoʻohana ʻana i kahi ʻano kānana a me nā ʻanuʻu centrifugation e wehe i nā haumia.
He ʻoi aku ka maikaʻi o ke ʻano o ka immersion alkaline ma mua o nā ʻano hana ʻē aʻe, me ka DS kiʻekiʻe a me ka maʻemaʻe, ke kumu kūʻai haʻahaʻa, a me ka scalability maʻalahi. Hiki ke hoʻohana ʻia ke ʻano hana no ka hana ʻana i ka HPMC me nā waiwai like ʻole ma o ka hoʻololi ʻana i nā kūlana hopena e like me ka mahana, ke kaomi, a me ka ʻike.
Eia nō naʻe, aia kekahi mau hemahema o ke ʻano. ʻO ka hoʻohana ʻana i ka NaOH a me MC hiki ke hoʻokau i ka palekana a me nā pilikia o ke kaiapuni, a hiki i ke kaʻina hana ke hoʻopau i ka manawa a koi i ka nui o ka ikehu.
I ka hopena, ʻo ke ʻano hana immersion alkaline kahi ala i hoʻohana nui ʻia no ka hana ʻana i ka HPMC. ʻO ke ala e pili ana i ka hopena o ka cellulose me NaOH, PO, a me MC ma lalo o kekahi mau kūlana, ukali ʻia e ka hoʻomaʻemaʻe a me ka maloʻo. ʻOiai he mau hemahema ke ala, ʻo kāna mau mea maikaʻi e lilo ia i koho kaulana no nā noi ʻoihana a me nā lāʻau lapaʻau.
Ka manawa hoʻouna: Apr-23-2023