Hydroxy Ethyl Cellulose: He mea kōkua nui i ka hoʻokumu ʻana i nā lāʻau lapaʻau

ʻO ka Hydroxyethyl cellulose (HEC) he polymer non-ionic wai-soluble i loaʻa mai ka cellulose, i hoʻohana nui ʻia i ka ʻoihana lāʻau lapaʻau ma ke ʻano he mea kōkua nui i nā hana lāʻau. Loaʻa iā HEC nā waiwai like ʻole, me ka mānoanoa, ka hoʻopaʻa ʻana, a me ka hoʻokuʻu ʻana, e lilo ia i mea kōkua maikaʻi loa no ka nui o nā noi. Ma kēia ʻatikala, e ʻimi mākou i nā noi like ʻole o HEC i nā ʻano lāʻau lapaʻau a me kāna mau waiwai e lilo ai ia i mea hoʻokō pono i ka ʻoihana lāʻau.

1. Ka hoʻoheheʻe a me ka launa pū

Hiki ke hoʻoheheʻe ʻia ka HEC i loko o ka wai a kūpono me nā ʻano mea hoʻoheheʻe ākea, me ka waiʻona, glycols, a me ka wai-miscible organic solvents. ʻO kēia ka mea e hoʻonui ai i nā ʻano lāʻau lapaʻau like ʻole, e like me ka waha, topical, a me ka hoʻoponopono makua. He kūpono hoʻi ia me nā ʻano mea ʻokoʻa ʻē aʻe, me nā polymers, surfactants, a me nā mea hoʻohui ʻē aʻe, e maʻalahi ai ke hoʻohui ʻia i loko o nā ʻano lāʻau lapaʻau like ʻole.

2. ʻO ka mānoanoa a me ke kau ʻana

ʻO ka HEC kahi mea mānoanoa maikaʻi loa a me ka hoʻokuʻu ʻana ma muli o kona hiki ke hana i kahi ʻano gel-like i ka wā i hoʻomaʻemaʻe ʻia. Hoʻohana ʻia kēia waiwai i ka hoʻokumu ʻana i nā hoʻokuʻu waha a me nā emulsions, kahi e kōkua ai i ka mālama ʻana i ke kūpaʻa a me ke kūlike o ka huahana. He mea maikaʻi nō hoʻi ia i ka hoʻokumu ʻana i nā huahana topical, e like me nā gels a me nā creams, kahi e kōkua ai i ka hāʻawi ʻana i kahi ʻano maʻalahi a paʻa.

3. Pilikino

Loaʻa iā HEC nā waiwai bioadhesive maikaʻi loa, ka mea i lilo ia i mea hoʻonaninani kūpono no ka hoʻokumu ʻana i nā huahana lāʻau lapaʻau. ʻO ka bioadhesion e pili ana i ka hiki o kahi mea ke pili i nā ʻili olaola, e like me ka ʻili a i ʻole ka mucous membrane. ʻO nā waiwai bioadhesive o HEC he mea pono ia i ka hoʻokumu ʻana i nā ʻōnaehana lawe lāʻau transdermal, kahi e kōkua ai i ka hoʻomaikaʻi ʻana i ka pili ʻana o ka pā i ka ʻili.

4. Hoʻokuʻu ʻia

He mea pono hoʻi ʻo HEC i ka hoʻokumu ʻana i nā huahana lāʻau e pono ai ka hoʻokuʻu ʻia. ʻO kona hiki ke hana i kahi ʻano gel-like i ka wā i hoʻomaʻemaʻe ʻia e lilo ia i mea kōkua kūpono no ka hoʻokumu ʻana i nā huahana lāʻau lapaʻau hoʻokuʻu ʻia. ʻO ke ʻano o ka gel-like e kōkua i ka mālama ʻana i ka hoʻokuʻu ʻana o ka lāʻau i kahi manawa lōʻihi, hiki ke kōkua i ka hoʻomaikaʻi ʻana i ka hoʻokō ʻana o ka maʻi a hōʻemi i ka pinepine dosing.

5. Paʻa

He mea hoʻonui paʻa ʻo HEC e hiki ke kū i ka nui o nā kūlana kaʻina hana, me nā mahana kiʻekiʻe a me nā ikaika shear. ʻO kēia ka mea e pono ai i ka hoʻokumu ʻana i nā huahana lāʻau e koi ai i ka hoʻoili wela kiʻekiʻe, e like me nā huahana lyophilized. ʻO kona kūpaʻa pū kekahi e kōkua i ka mālama ʻana i ka paʻa o ka huahana lāʻau i ka wā o ka mālama ʻana, he mea koʻikoʻi no ka mālama ʻana i ka pono o ka lāʻau.

6. Palekana

ʻO HEC kahi mea hoʻohana palekana i hoʻohana ʻia i ka ʻoihana lāʻau lapaʻau no nā makahiki he nui. He meaʻawaʻawaʻole a me ka hoʻonāukiukiʻole, kahi e kūpono ai no ka hoʻohanaʻana i nā huahana lāʻau lapaʻau waha a me ka topical. Hoʻopili pū ia me kahi ākea o nā mea lāʻau lapaʻau ikaika (API), kahi e maʻalahi ai ka hoʻohui ʻana i nā ʻano lāʻau lapaʻau like ʻole.

ʻO nā noi o HEC i nā hana lāʻau

He mea kōkua nui ka HEC e loaʻa ai nā noi i nā ʻano hana lāʻau lapaʻau. Aia kekahi o kāna mau noi:

1. ʻO ka hoʻokuʻu waha a me nā emulsions: He mea pono ʻo HEC i ka hoʻokumu ʻana i nā hoʻopiʻi waha a me nā emulsions, kahi e kōkua ai e mālama i ka paʻa a me ke kūlike o ka huahana.
2. Nā huahana Topical: He mea pono ka HEC i ka hoʻokumu ʻana i nā huahana topical, e like me nā gels a me ka creams, kahi e kōkua ai i ka hāʻawi ʻana i kahi ʻano maʻalahi, kūlike a hoʻomaikaʻi i ka bioadhesion.
3. ʻO nā ʻōnaehana lawe lāʻau transdermal: ʻO nā waiwai bioadhesive o HEC e pono ai i ka hoʻokumu ʻana i nā ʻōnaehana lawe lāʻau transdermal,

Hoʻohana pū ʻia ʻo HEC ma ke ʻano he mānoanoa a me ka hoʻopaʻa ʻana i nā ʻano mea hoʻonaninani a me nā huahana mālama pilikino e like me nā lotions, shampoos, a me nā niho niho. I ka ʻoihana meaʻai, hoʻohana ʻia ia ma ke ʻano he mānoanoa, binder, a me ka emulsifier i nā huahana e like me nā ʻaʻahu saladi, ice cream, a me nā mea i kālua ʻia.

ʻO kekahi o nā pōmaikaʻi nui o HEC ʻo kona hiki ke hana i kahi gel ke hui pū ʻia me ka wai. Hana kēia i mea hoʻohui kūpono no nā ʻōnaehana lawe lāʻau e koi ai i ka hoʻokuʻu mau ʻana o nā mea hana. Hoʻohana ʻia nā waiwai hana gel o HEC i nā huahana ho'ōla ʻeha a ma ke ʻano he uhi no nā papa a me nā capsules.

He biocompatible a biodegradable hoʻi ʻo HEC, e lilo ia i mea hoʻonaninani no nā ʻōnaehana lawe lāʻau. Ua hoʻohana ʻia i nā ʻōnaehana lawe lāʻau like ʻole, me nā microspheres, nanoparticles, a me nā hydrogels. Hiki ke hoʻohana ʻia ʻo HEC no ka hoʻopili ʻana i nā mea hana, pale iā lākou mai ka hōʻino ʻana a hoʻonui i ko lākou kūpaʻa.

I ka hopena, ʻo HEC kahi mea hoʻohana nui i loaʻa i nā noi he nui i ka ʻoihana lāʻau lapaʻau, cosmetic, a me nā meaʻai. ʻO kāna mau waiwai kūʻokoʻa e lilo ia i mea hoʻohui kūpono no nā ʻōnaehana lawe lāʻau, nā huahana ho'ōla ʻeha, a me nā noi ʻē aʻe. Ke hoʻomau nei ka noiʻi ʻana, e hoʻomau ʻia ka hoʻohana ʻana o HEC e ulu a hoʻonui i nā wahi hou.