Nā mea e pili ana i ka viscosity o ka hydroxypropyl methylcellulose

ʻO ka Hydroxyl methyl cellulose (HPMC) he polymer i hoʻohana nui ʻia i nā lāʻau lapaʻau, nā mea hoʻonaninani, nā meaʻai a me nā ʻoihana ʻē aʻe. ʻO kāna mau hiʻohiʻona kūikawā, e like me ka viscosity kiʻekiʻe, ka wai maikaʻi-soluble a me ka hiki ke hoʻokumu i ka membrane, e lilo ia i mea koʻikoʻi i nā ʻano like ʻole. ʻO ka viscosity ka hiʻohiʻona nui o HPMC i kāna noi. Hoʻopili ʻia ka viscosity o HPMC e nā mea like ʻole, e like me ka neʻe ʻana, ka mahana, ka pH, a me ke kaumaha molekala. ʻO ka hoʻomaopopo ʻana i nā mea e pili ana i ka viscosity HPMC he mea nui ia no ka optimization. Kūkākūkā kēia ʻatikala i nā mea e pili ana i ka viscosity o ka hydroxylopyl methyl cellulose.

Kakau ma

ʻO ka manaʻo o ka HPMC kekahi o nā kumu nui e pili ana i kona viscosity. Hoʻonui ka viscosity o ka hopena HPMC me ka piʻi ʻana o ka ʻike. Ma kahi haʻahaʻa haʻahaʻa, hoʻopuehu nui ʻia ke kaulahao polymer HPMC i ka solvent, no laila ua haʻahaʻa ka viscosity. Eia nō naʻe, ma kahi kiʻekiʻe kiʻekiʻe, ʻo ke kaulahao polymer e launa pū kekahi me kekahi, e hopena i ka viscosity kiʻekiʻe. No laila, ua like ka viscosity o HPMC i ka hoʻopaʻa ʻana o ka polymer. Hoʻopili pū ka manaʻo i ka hana gelization o HPMC. Hiki i ka HPMC kiʻekiʻe ke hana i ka gel, he mea nui loa ia i ka ʻoihana lāʻau lapaʻau a me ka meaʻai.

mahana wela

ʻO ka mahana kekahi kumu nui e pili ana i ka viscosity o ka hydroxylopenyl cellulose. Hoʻemi ka viscosity o HPMC me ka piʻi ʻana o ka mahana. ʻOi aku ke kahe o ke kaulahao polimer HPMC i kahi wela kiʻekiʻe, e hopena i ka viscosity haʻahaʻa. Ke hoʻohālikelike ʻia me nā haʻina haʻahaʻa haʻahaʻa, ʻoi aku ka ʻike o ka hopena o ka mahana ma ka viscosity HPMC. ʻO ka piʻi ʻana o ka mahana e pili pū i ka solubility o HPMC. Ma kahi wela kiʻekiʻe, e emi ana ka solubility o ka HPMC, ka hopena o ka emi ʻana o ka viscosity ma muli o ka emi ʻana o ke kaulahao entanglement.

pH

ʻO ka pH o ka hopena HPMC kekahi mea nui e pili ana i kona viscosity. ʻO ka HPMC kahi polymer acidic nāwaliwali, me kahi PKA ma kahi o 3.5. No laila, pili ka viscosity o ka hopena HPMC i ka pH o ka hopena. Ma lalo o ka pH waiwai kiʻekiʻe ma mua o PKA, ka carboxylic acid paʻakai pūʻulu o ka polymer ma lalo o ka protonization, ka mea i hoʻonui i ka solubility o HPMC, a ua emi ka viscosity ma muli o ka emi o ka hydrogen paʻa o ka molecular interconsiscence. Ma lalo o ka pH waiwai ma lalo o PKA, he nui ka hui waikawa carboxylic o ka polymer, kahi i hoʻohaʻahaʻa ai i ka solubility a me ka viscosity kiʻekiʻe ma muli o ka hoʻonui ʻana i nā paʻa hydrogen. No laila, ʻo ka waiwai pH maikaʻi loa o ka hopena HPMC e pili ana i ka noi i manaʻo ʻia.

Kaumaha molekula

ʻO ke kaumaha molekala o HPMC kekahi mea nui e pili ana i kona viscosity. ʻO ka HPMC he polymer polymer. Ke piʻi aʻe ka paona molekala o ka polymer, e piʻi ka viscosity o ka hopena HPMC. ʻO kēia no ka mea ua hoʻopili ʻia ke kaulahao HPMC kiʻekiʻe molekala kaumaha, e hoʻonui ai i ka viscosity. Hoʻopili pū ka paona molekala o ka polymer i ka gelization HPMC. ʻOi aku ka maikaʻi o ka polimer HPMC ma mua o nā polymers kaumaha haʻahaʻa.

Paakai

ʻO ka hoʻohui ʻana i ka paʻakai i ka hopena HPMC hiki ke hoʻopilikia nui i kona viscosity. Hoʻopili ka paʻakai i ka ikaika ion o ka hopena HPMC, e hoʻololi i ka pilina o nā polymers. ʻO ka maʻamau, ʻo ka hoʻohui ʻana i ka paʻakai i ka hoʻonā HPMC e hoʻemi i ka viscosity. ʻO kēia ke kumu o ka emi ʻana o ka ikaika o ka ion o ka hopena ma waena o ka ikaika molekula ma waena o ke kaulahao polymer HPMC, a laila e hōʻemi ana i ka hoʻohaʻahaʻa ʻana o ke kaulahao entanglement, no laila ua hoʻemi ʻia ka viscosity. ʻO ka hopena o ka paʻakai ma ka viscosity o ka HPMC solution e pili ana i ke ʻano a me ka neʻe ʻana o ka paʻakai.

i ka hopena

ʻO ka viscosity o ka hydroxydal cibolin kahi kīʻaha koʻikoʻi e pili ana i kāna noi ma nā ʻoihana like ʻole. ʻO nā mea e pili ana i ka viscosity HPMC e pili ana i ka neʻe ʻana, ka mahana, ka pH, ke kaumaha molekala a me ka paʻakai. ʻO ka hoʻomaopopo ʻana i kēia mau mea i ka viscosity HPMC he mea nui e hoʻonui i kona hoʻohana ʻana i nā noi like ʻole. Hiki ke hoʻololi pono ʻia ka hoʻonā HPMC e hoʻokō i ka viscosity i koi ʻia i kikoʻī.