Me yasa HEMC ya fi HPMC zabi?

Hypromellose (HPMC) da hydroxyethylmethylcellulose (HEMC) su ne nau'ikan cellulose guda biyu da ake amfani da su tare da aikace-aikace a cikin masana'antun magunguna, abinci da kayan kwalliya. Ko da yake HPMC da HEMC suna da kamanceceniya da yawa, amma sun bambanta ta wasu hanyoyi, suna sa ɗayan ya fi ɗayan don wasu aikace-aikace.

HEMC shine ether cellulose da aka gyara wanda aka samu ta hanyar amsa methyl cellulose tare da ethylene oxide da ethyl chloride, sa'an nan kuma maye gurbin ethyl don hydroxyl. Saboda haka, HEMC yana da matsayi mafi girma na maye gurbin (DS) fiye da HPMC. DS yana nufin matsakaicin adadin abubuwan maye da naúrar glucose, wanda ke shafar halayen jiki da sinadarai na polymer. Gabaɗaya, mafi girma DS yana haifar da ingantacciyar narkewa a cikin abubuwan kaushi na halitta, saurin rushewa, da haɓaka haɓakar sha ruwa. DS na HEMC yawanci shine 1.7-2.0, yayin da DS na HPMC yawanci tsakanin 1.2 da 1.5.

Wani fa'ida ta musamman na HEMC akan HPMC shine kyakkyawan ƙarfin riƙewar ruwa, yana mai da shi manufa don ƙirar mannewa, kayan gini da sauran samfuran da ke buƙatar riƙe ruwa mai kyau. HEMC kuma yana da juriya ga harin ƙananan ƙwayoyin cuta fiye da HPMC kuma yana da tsawon rai. Ƙara yawan hydrophobicity na HEMC da kasancewar ƙungiyoyin ethyl a cikin kashin baya sun sa ya zama kyakkyawan emulsifier kuma zai iya inganta kwanciyar hankali na dogon lokaci na emulsion.

Wani fa'idar amfani da HEMC shine dacewarsa da yawancin sauran sinadarai, wanda ke ba da gudummawar haɓakarsa a aikace-aikace daban-daban. Bugu da ƙari, HEMC yana da kyawawan abubuwan samar da fina-finai, wanda ya sa ya zama mai amfani don samar da sutura da masu ɗaure a cikin samar da allunan, kwayoyi da granules.

A gefe guda, HPMC yana da mafi kyawun kayan gelling thermal, wanda ya sa ya zama kyakkyawan zaɓi don ƙirar magunguna masu saurin-saki waɗanda ke buƙatar gels masu zafin jiki. Har ila yau, HPMC yana da mafi kyawun narkewar ruwa kuma ba shi da wuya a samar da coagglomerates, waɗanda ba za su iya narkewa na polymers a cikin bayani ba.

A ƙarshe, duka HEMC da HPMC sune samfuran cellulose masu mahimmanci waɗanda ke ba da fa'idodi daban-daban dangane da aikace-aikacen. HEMC yana da mafi kyawun riƙe ruwa, emulsification, da dacewa tare da sauran sinadarai, yayin da HPMC yana da kyawawan kaddarorin thermogelling da narkewar ruwa. Saboda haka, zaɓi tsakanin HEMC da HPMC ya dogara da aikace-aikacen da ake so, tsarin masana'antu da buƙatun samfurin ƙarshe.