Hydroxypropylmethylcellulose (HPMC) yana ɗaya daga cikin abubuwan da aka fi amfani da su a cikin masana'antar harhada magunguna da masana'antar abinci da kuma masana'antar gini. Ɗaya daga cikin manyan fa'idodin HPMC shine ikon riƙe ruwa, wanda ya sa ya dace don aikace-aikace iri-iri. Ayyukan riƙe ruwa na HPMC yana shafar abubuwa da yawa, ciki har da danko, abun ciki, zafin yanayi da tsarin kwayoyin halitta.
danko
Ɗaya daga cikin manyan abubuwan da ke shafar aikin riƙe ruwa na HPMC shine danko. Dankowa yana nufin kauri ko juriya zuwa kwararar abu. Don HPMC, mafi girman danko, mafi girman riƙewar ruwa.
Mafi girman danko HPMC yana da mafi girman nauyin kwayoyin halitta, wanda ke nufin dogon sarƙoƙi na polymer. Dogayen sarƙoƙi suna sa ya zama da wahala ga ƙwayoyin ruwa su motsa cikin kayan. Wannan yana haifar da riƙewar ruwa mafi girma yayin da kwayoyin ruwa ke cikin tarko a cikin matrix polymer, wanda ke haɓaka ƙarfin gaba ɗaya na matrix.
abun ciki
Wani abu da ke shafar aikin riƙe ruwa na HPMC shine abun ciki. HPMC ya ƙunshi manyan sassa guda biyu tare da matakan hydrophilicity daban-daban, wato metoxyl da hydroxypropyl. Mafi girman abun ciki na hydroxypropyl a cikin HPMC, mafi girman ƙarfin riƙe ruwa.
Ƙungiyar hydroxypropyl a cikin HPMC tana ƙayyade aikin riƙewar ruwa. Waɗannan ƙungiyoyi suna jan hankali kuma suna riƙe da kwayoyin ruwa, suna haifar da kumburin HPMC. Wannan kumburi yana taimakawa wajen samar da shamaki wanda ke jinkirta sakin ruwa daga HPMC. Ƙungiyoyin methoxy, a gefe guda, ba su da hydrophilic kamar ƙungiyoyin hydroxypropyl don haka ba sa taimakawa sosai ga iyawar ruwa.
yanayin zafi
Yanayin yanayi wani abu ne wanda ke shafar aikin riƙe ruwa na HPMC. Yayin da zafin jiki ke ƙaruwa, ƙarfin riƙe ruwa na HPMC yana raguwa. Wannan yana faruwa saboda a yanayin zafi mafi girma, sarƙoƙi na polymer na HPMC suna da ƙarin kuzarin motsi, kuma suna tafiya da sauri. Sakamakon haka, ana fitar da kwayoyin ruwa da sauri daga matrix polymer. Hakanan, a ƙananan yanayin zafi, ƙwayoyin ruwa sun fi daidaitawa a cikin matrix na HPMC, yana haifar da riƙe ruwa mafi girma.
Sabili da haka, yana da mahimmanci don sarrafa yanayin zafin jiki yayin aikin masana'anta don tabbatar da daidaito da amincin aikin riƙe ruwa.
Tsarin Kwayoyin Halitta
Ƙarfin riƙewar ruwa na HPMC shima yana shafar tsarin sa na ƙwayoyin cuta. Tsarin kwayoyin halitta na HPMC an ƙaddara ta matakin maye gurbin (DS) da rarraba nauyin kwayoyin halitta.
Matsayin maye yana nufin matakin da ƙungiyoyin hydroxypropyl ke maye gurbin ƙungiyoyin hydroxyl na cellulose. HPMC tare da babban mataki na canji yana da mafi girman ƙarfin riƙe ruwa. Sabanin haka, HPMC tare da ƙaramin digiri na maye yana da ƙaramin ƙarfin riƙe ruwa.
Rarraba nauyin kwayoyin halitta na HPMC kuma yana rinjayar iyawar riƙewar ruwa. Mafi girman nauyin kwayoyin halitta, mafi girman ƙarfin riƙewar ruwa, yayin da manyan kwayoyin halitta suna samar da madaidaicin tsarin matrix wanda ke riƙe da kwayoyin ruwa sosai.
a karshe
HPMC abu ne mai fa'ida sosai saboda kyawawan abubuwan riƙe ruwa. Ƙarfin riƙewar ruwa na HPMC yana da alaƙa kai tsaye zuwa danko, abun ciki, zafin yanayi da tsarin kwayoyin halitta. Saboda haka, zabar HPMC da ya dace don takamaiman aikace-aikacen yana buƙatar yin la'akari da waɗannan abubuwan a hankali. Gabaɗaya, HPMC tana da inganci da inganci da inganci na samfura iri-iri a cikin masana'antu da yawa, gami da magunguna, abinci, da gini.
Lokacin aikawa: Agusta-30-2023