I-HPMC, noma i-Hydroxypropyl Methylcellulose, iyi-polymer yokwenziwa esetshenziswa kakhulu emikhakheni yezemithi, yokudla, yezimonyo neyokwakha. Inezici eziningi ezinhle kakhulu ezifana nokuncibilika, ukuzinza, ukucaca kanye nezakhiwo zefilimu njenge-thickener, i-adhesive, ifilimu yangaphambili, i-ejenti yokumisa kanye ne-colloid evikelayo.
Ngokuphathelene ne-viscosity ye-HPMC, kungumqondo oyinkimbinkimbi ngoba i-viscosity ithintwa izici eziningi, njengokugxila, isisindo samangqamuzana, i-solvent, izinga lokushisa kanye ne-shear rate.
Ubudlelwano phakathi kwesisindo se-molecular and viscosity: Isisindo samangqamuzana e-HPMC singenye yezinto ezibalulekile ezinquma i-viscosity yayo. Ngokuvamile, ukuphakama kwesisindo samangqamuzana, kukhuphuka i-viscosity ye-HPMC. Ngakho-ke, abakhiqizi bavame ukuhlinzeka ngemikhiqizo ye-HPMC enesisindo samangqamuzana ahlukene ukuze ihlangabezane nezidingo zezimboni ezahlukene. Isisindo samangqamuzana ngokuvamile sivezwa njengenani lika-K (njenge-K100, K200, njll.). Uma inani lika-K likhulu, i-viscosity iyanda.
Umthelela wokugxilisa ingqondo: I-viscosity yesisombululo se-HPMC emanzini iyanda ngokukhula kokugxila. Isibonelo, i-concentration engu-1% yesisombululo se-HPMC ingaba ne-viscosity izikhathi eziningana ngaphezu kwalokho kwesisombululo sokuhlushwa esingu-0.5%. Lokhu kuvumela i-viscosity yesixazululo ukuthi ilawulwe ngokulungisa ukugxila kwe-HPMC kuhlelo lokusebenza.
Umthelela we-solvent: I-HPMC ingancibilika emanzini noma kwizincibilikisi eziphilayo, kodwa izincibilikisi ezihlukene zithinta i-viscosity yayo. Ngokuvamile, i-HPMC inokunyibilika okuhle emanzini futhi i-viscosity yesixazululo iphezulu, kuyilapho i-viscosity kuzinyibilikisi zemvelo iyahlukahluka kuye ngokuthi i-polarity yesincibilikizo kanye nezinga lokushintsha kwe-HPMC.
Umthelela wezinga lokushisa: I-viscosity yesisombululo se-HPMC iyashintsha nezinga lokushisa. Ngokuvamile, i-viscosity yesisombululo se-HPMC iyehla lapho izinga lokushisa likhuphuka. Lokhu kungenxa yokuthi ukwanda kwezinga lokushisa kuholela ekuhambeni okusheshayo kwamangqamuzana kanye nokwanda kwe-fluidity yesisombululo, okunciphisa i-viscosity.
Umthelela wesilinganiso sokugunda: Isixazululo se-HPMC uketshezi olungezona olwase-Newton, futhi i-viscosity yalo iyashintsha ngesilinganiso sokugunda. Lokhu kusho ukuthi ngesikhathi sokugubha noma ukupompa, i-viscosity iyashintsha ngokushuba kokusebenza. Ngokuvamile, isixazululo se-HPMC sibonisa izici zokugunda kwe-shear, okungukuthi, i-viscosity iyancipha ngamanani aphezulu wokugunda.
Amamaki kanye nokucaciswa kwe-HPMC: Amabanga ahlukene emikhiqizo ye-HPMC nawo anomehluko omkhulu ku-viscosity. Isibonelo, umkhiqizo we-HPMC wezinga eliphansi le-viscosity ungase ube ne-viscosity engu-20-100 mPas ekugxiliseni okungu-2%, kuyilapho umkhiqizo we-HPMC wezinga eliphezulu le-viscosity ungase ube ne-viscosity efika ku-10,000-200,000 mPas ekugxiliseni okufanayo. Ngakho-ke, lapho ukhetha i-HPMC, kubalulekile ukukhetha ibanga elifanele le-viscosity ngokusekelwe kuzidingo ezithile zohlelo lokusebenza.
Izindlela zokuhlola ezijwayelekile: I-viscosity ye-HPMC ivamise ukukalwa nge-viscometer noma i-rheometer. Izindlela zokuhlola ezijwayelekile zifaka i-viscometer ejikelezayo kanye ne-capillary viscometer. Izimo zokuhlola ezifana nezinga lokushisa, ukugxilisa ingqondo, uhlobo lwe-solvent, njll. zingaba nomthelela omkhulu emiphumeleni, ngakho le mingcele idinga ukulawulwa ngokuqinile phakathi nokuhlolwa.
I-viscosity ye-HPMC iyipharamitha eyinkimbinkimbi ethintwa izici eziningi, futhi ukulungiswa kwayo kuyenza isetshenziswe kabanzi ezinhlelweni ezihlukahlukene. Kungakhathaliseki ukuthi kusezimbonini zokudla, ezekhemisi, zezinto zokwakha noma zezimonyo, ukuqonda nokulawula i-viscosity ye-HPMC kungenye yezinto ezibalulekile zokuqinisekisa ikhwalithi nokusebenza komkhiqizo.
Isikhathi sokuthumela: Aug-28-2024