Iyini i-HPMC excipient?

IHydroxypropyl methylcellulose (HPMC) iyisakhi esisetshenziswa emikhiqizweni yezemithi nokudla. Kuyi-polymer yokwenziwa etholakala ku-cellulose futhi isetshenziswa njenge-ejenti yokuqina, i-stabilizer, i-emulsifier, ne-ejenti elengayo. I-HPMC iyimpushana emhlophe, engenaphunga, enganambitheki encibilika emanzini abandayo futhi engancibiliki emanzini ashisayo. Yaziwa nangokuthi i-hypromellose futhi isetshenziswa ezinhlelweni ezahlukahlukene, kufaka phakathi imithi, ukudla, izimonyo, kanye nemikhiqizo yezimboni.

I-HPMC iyi-polymer engeyona i-ionic, encibilika emanzini esetshenziselwa ukwakha amajeli, ukujiya izixazululo, nokusimamisa ama-emulsion. Kuyi-excipient eguquguqukayo engasetshenziswa ekwakhiweni okuhlukahlukene, okuhlanganisa amaphilisi, amaphilisi, okhilimu, amafutha okugcoba, nokumiswa okwesikhashana. I-HPMC iphinde isetshenziswe njenge-ejenti enamathelayo yamaphilisi namaphilisi, njenge-emulsifier kumakhilimu namafutha okugcoba, nanjenge-stabilizer ekumisweni.

I-HPMC iyisamukeli esiphephile nesisebenzayo esigunyazwe i-US Food and Drug Administration (FDA) ukuze sisetshenziswe emikhiqizweni yezemithi nokudla. Ayinabuthi futhi ayicunuli, futhi ayinayo imiphumela emibi eyaziwayo. I-HPMC futhi ayiyona i-allergenic, okuyenza ibe isisetshenziswa esifanelekile kubantu abazwelayo.

I-HPMC iyisamukeli esingabizi kakhulu esingasetshenziswa ekwakhiweni okuhlukahlukene. Kulula futhi ukuyisebenzisa, njengoba inyibilika emanzini abandayo futhi ingafakwa kalula ekuhlanganiseni. I-HPMC nayo izinzile futhi ineshalofu lesikhathi eside, okuyenza ibe isisetshenziswa esifanelekile sokugcina isikhathi eside.

Sekukonke, i-HPMC iyisamukeli esisebenza ngezindlela eziningi esisetshenziswa emikhiqizweni eyahlukene yezemithi nokudla. Iphephile, iyasebenza, futhi iyonga, futhi ingasetshenziswa ekuhlanganiseni okuhlukahlukene. I-HPMC futhi kulula ukuyisebenzisa futhi ineshalofu ende yokuphila, okuyenza ibe isamukeli esifanelekile sokugcina isikhathi eside.