Luyini uhlelo lwe-CMC ekwakhiweni kwemithi?

I-Carboxymethylcellulose (CMC) iyisakhi esisetshenziswa kakhulu ekwakhiweni kwemithi. I-polysaccharide encibilika emanzini etholakala ku-cellulose, eyakhiwe amayunithi e-glucose axhunywe ndawonye ngamabhondi e-glycosidic. I-CMC iyimpushana engeyona i-ionic, ayinambitheki, ayinaphunga, futhi iyimpushana emhlophe engancibiliki kuzincibilikisi eziningi eziphilayo. Isetshenziswa ekwenziweni kwemithi ukuthuthukisa ukuzinza, i-bioavailability, nokuphepha kwezidakamizwa.

I-CMC isetshenziswa ekwenziweni okuhlukahlukene kwemithi, okubandakanya amaphilisi, amaphilisi, ukumiswa, ama-emulsions, namafutha okugcoba. Isetshenziswa njenge-binder, i-disintegrant, i-ejenti yokumisa, i-emulsifying ejenti, i-lubricant, kanye ne-stabilizer. Ibuye isetshenziselwe ukwandisa i-viscosity ye-formulation kanye nokuthuthukisa izakhiwo zokugeleza kwezimpushana.

I-CMC isetshenziswa kumaphilisi nama-capsules ukuthuthukisa ukugeleza kwezakhiwo zempushana, ukwandisa ukucindezelwa kwempushana, kanye nokwenza ngcono ukuhlakazeka nokuqedwa kwethebhulethi noma i-capsule. Ibuye isetshenziswe njengesibophezelo sokubamba ithebhulethi noma i-capsule ndawonye. I-CMC isetshenziswa ekumisweni ukuze kuthuthukiswe ukuzinza kokumiswa kanye nokwandisa i-viscosity yokumiswa. Ibuye isetshenziswe njenge-emulsifying ejenti ukuthuthukisa ukuzinza kwama-emulsions.

I-CMC isetshenziselwa amafutha okugcoba ukuthuthukisa ukuzinza kwamafutha kanye nokwandisa i-viscosity yamafutha. Ibuye isetshenziselwe ukugcoba ukunciphisa ukungqubuzana phakathi kwamafutha kanye nesikhumba.

I-CMC ngokuvamile iphephile futhi ayinabo ubuthi. Ngokuvamile yaziwa ngokuthi iphephile (GRAS) yi-US Food and Drug Administration (FDA). Igunyazwe futhi yi-European Medicines Agency (EMA) ukuze isetshenziswe ekwenziweni kwemithi.

I-CMC iyisakhi esibalulekile ekwakhekeni kwemithi. Isetshenziselwa ukuthuthukisa ukuzinza, i-bioavailability, nokuphepha kwezidakamizwa. Ngokuvamile iphephile futhi ayinabo ubuthi futhi igunyazwe i-FDA kanye ne-EMA ukuze isetshenziswe ekwenziweni kwemithi.