Ingabe I-Sodium Carboxymethyl Cellulose Iyingozi Emzimbeni Womuntu?

I-Sodium carboxymethyl cellulose (CMC) ngokuvamile ithathwa njengephephile (i-GRAS) ukuze isetshenziswe iziphathimandla ezilawulayo ezifana ne-Food and Drug Administration (FDA) e-United States kanye ne-European Food Safety Authority (EFSA) eYurophu uma isetshenziswa ngokuvumelana nesimiso esimisiwe. imihlahlandlela yokuphepha nangaphakathi kwemikhawulo evumelekile. Nakhu okufingqiwe kokucatshangelwa kokuphepha okuhlotshaniswa ne-sodium carboxymethyl cellulose:

1. Ukugunyazwa Kokulawula: I-CMC igunyazelwe ukusetshenziswa njengesithako sokudla emazweni amaningi emhlabeni jikelele, okuhlanganisa i-United States, European Union, Canada, Australia, kanye ne-Japan. Ifakwe ohlwini nama-ejensi ahlukahlukene alawulayo njengesithako esivunyelwe sokudla esinemikhawulo ethile yokusetshenziswa kanye nokucaciswa.
2. Izifundo Ze-Toxicological: Ucwaningo olunzulu lwe-toxicological lwenziwe ukuze kuhlolwe ukuphepha kwe-CMC ukuze isetshenziswe abantu. Lezi zifundo zibandakanya ukuhlolwa kobuthi obunamandla, obungahlali isikhathi eside, kanye nokuhlolwa kwe-mutagenicity, genotoxicity, kanye ne-carcinogenicity. Ngokusekelwe kudatha etholakalayo, i-CMC ithathwa njengephephile ukuze isetshenziswe abantu emazingeni avunyelwe.
3. I-Daily Intake (ADI) eyamukelekayo: Ama-ejensi alawulayo asungule amanani amukelekayo okudla kwansuku zonke (ADI) e-CMC ngokusekelwe ezifundweni zobuthi kanye nokuhlola kokuphepha. I-ADI imele inani le-CMC elingadliwa nsuku zonke empilweni yonke ngaphandle kobungozi obubonakalayo empilweni. Amanani e-ADI ayahluka phakathi kwama-ejensi alawulayo futhi avezwa ngama-milligram ngekhilogremu yesisindo somzimba ngosuku (mg/kg bw/ngosuku).
4. I-Allergenicity: I-CMC isuselwa ku-cellulose, i-polysaccharide eyenzeka ngokwemvelo etholakala ezindongeni zamaseli ezitshalo. Akwaziwa ukuthi kubangele ukungezwani nomzimba kumphakathi jikelele. Kodwa-ke, abantu abane-allergies eyaziwayo noma ukuzwela kokuphuma kokuphuma ku-cellulose kufanele baqaphele futhi baxhumane nochwepheshe bezempilo ngaphambi kokudla imikhiqizo equkethe i-CMC.
5. Ukuphepha Kokugaya Ukudla: I-CMC ayimuncwa uhlelo lokugaya ukudla komuntu futhi idlula emgudwini wamathumbu ngaphandle kokwenziwa i-metabolized. Kubhekwa njengento engeyona enobuthi futhi engacasuli i-mucosa yokugaya. Nokho, ukusetshenziswa ngokweqile kwe-CMC noma okunye okuphuma ku-cellulose kungase kubangele ukungakhululeki kwamathumbu, ukuqunjelwa, noma isifo sohudo kwabanye abantu.
6. Ukusebenzisana Nemithi: I-CMC akwaziwa ukuthi isebenzisana nemithi noma ithinte ukumuncwa kwayo emgudwini wamathumbu. Kuthathwa njengokuhambisana nokwakheka kwemithi eminingi futhi kuvame ukusetshenziswa njengesamukeli kumafomu omthamo womlomo njengamaphilisi, amaphilisi, kanye nokulengiswa.
7. Ukuphepha Kwemvelo: I-CMC iyabola futhi ihambisana nemvelo, njengoba itholakala emithonjeni evuselelekayo efana ne-wood pulp noma i-cotton cellulose. Iphuka ngokwemvelo endaweni ngesenzo se-microbial futhi ayiqoqi emhlabathini noma ezinhlelweni zamanzi.

I-sodium carboxymethyl cellulose (CMC) ithathwa njengephephile ukuthi isetshenziswe uma isetshenziswa ngokuhambisana neziqondiso zokulawula kanye namazinga okuphepha amisiwe. Ifundelwe kabanzi ngobuthi bayo, i-allergenicity, ukuphepha kokugaya ukudla, kanye nomthelela wemvelo, futhi ivunyelwe ukusetshenziswa njengesithasiselo sokudla kanye nesengezo semithi emazweni amaningi emhlabeni jikelele. Njenganoma yisiphi isithako sokudla noma isithasiselo, abantu kufanele basebenzise imikhiqizo equkethe i-CMC ngokusesilinganisweni njengengxenye yokudla okunomsoco futhi baxhumane nochwepheshe bezokunakekelwa kwempilo uma benemikhawulo ethile yokudla noma ukukhathazeka ngezokwelapha.