Ingabe i-hypromellose iyingozi emzimbeni?

IHypromellose, eyaziwa nangokuthi i-hydroxypropyl methylcellulose, iyi-semi-synthetic, inert, ne-polymer encibilika emanzini esetshenziswa kabanzi ezimbonini ezahlukahlukene. Ivamise ukusetshenziswa njengesengezo sokudla, i-thickener, emulsifier, futhi njengesithako semithi ekukhiqizeni amaphilisi, amaphilisi, kanye namalungiselelo e-ophthalmic. Kulesi sihloko, sizohlola ukuphepha kwe-hypromellose kanye nemiphumela yayo yezempilo engaba khona.

Ukuphepha kweHypromelose

I-Hypromellose ngokuvamile ibhekwa njengephephile ukuthi isetshenziswe yiziphathimandla ezihlukahlukene zokulawula, okuhlanganisa i-United States Food and Drug Administration (FDA), i-European Food Safety Authority (EFSA), kanye neKomidi Lochwepheshe Elihlangene le-FAO/WHO Lezithako Zokudla (JECFA). Ihlukaniswa njengesengezo sokudla se-GRAS (esivame ukuqashelwa njengesiphephile) yi-FDA, okusho ukuthi inomlando omude wokusetshenziswa okuphephile ekudleni futhi cishe ayinakubangela ukulimala uma idliwe ngamanani avamile.

Kwezemithi, i-hypromellose isetshenziswa kabanzi njengesithako esiphephile nesibekezelelwa kahle. Isohlwini lwe-US Pharmacopeia futhi isetshenziswa kabanzi ekukhiqizeni kokubili amafomu omthamo oqinile nawuketshezi. Ibuye isetshenziswe njengesithambisi samehlo futhi ithathwa njengephephile ukuthi isetshenziswe kumalensi okuxhumana, izinyembezi zokwenziwa, neminye imikhiqizo ye-ophthalmic.

Ucwaningo luye lwabonisa ukuthi i-hypromellose inobuthi obuncane bomlomo futhi ayimuncwa umzimba. Idlula emgudwini wamathumbu ngaphandle kokuphulwa, futhi ikhishwe endle. I-Hypromellose nayo ibhekwa njengephephile ukuthi isetshenziswe kwabesifazane abakhulelwe nabancelisa ibele, kanye nezingane, ngaphandle kwemiphumela emibi eyaziwayo.

Imiphumela Yezempilo Engaba Khona ye-Hypromellose

Nakuba i-hypromellose ngokuvamile ibhekwa njengephephile ukusetshenziswa, kunemiphumela ethile yezempilo engaba khona okufanele icatshangelwe.

Imiphumela Yamathumbu

I-Hypromellose iyi-polymer encibilika emanzini emunca amanzi futhi yakhe into efana nejeli lapho ihlangana noketshezi. Lokhu kungaholela ekwandeni kwe-viscosity emgudwini wamathumbu, okungase kubambezele isikhathi sokuhamba kokudla ngokusebenzisa uhlelo lokugaya ukudla. Lokhu kungase kubangele ukuqunjelwa, ukuqunjelwa, nokungakhululeki kwesisu kwabanye abantu, ikakhulukazi uma kusetshenziswe amanani amakhulu.

I-Allergic Reactions

Ukungezwani komzimba ne-hypromellose akuvamile, kodwa kungenzeka. Izimpawu zokungezwani komzimba zingase zihlanganise ukuqunjelwa, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi, noma umphimbo, ukuphefumula kanzima, kanye ne-anaphylaxis (ukusabela komzimba okunamandla, okungase kube yingozi empilweni). Uma uhlangabezana nanoma iyiphi yalezi zimpawu ngemva kokudla i-hypromellose, funa usizo lwezokwelapha ngokushesha.

Ukucasuka kwamehlo

I-Hypromellose ivame ukusetshenziswa njengesithambisi se-ophthalmic ekukhiqizeni amaconsi iso kanye namanye amalungiselelo e-ophthalmic. Nakuba ngokuvamile kubhekwa njengokuphephile ukusetshenziswa emehlweni, abanye abantu bangase babhekane nokucasuka kwamehlo noma eminye imiphumela emibi. Izimpawu zokucasuka kwamehlo zingase zihlanganise ububomvu, ukulunywa, ukuvutha, nokuklebhuka.

Ukusebenzisana Kwezidakamizwa

I-Hypromellose ingase ihlanganyele nemithi ethile, ikakhulukazi leyo edinga indawo ephansi ye-pH ukuze imunce. Lokhu kungenxa yokuthi i-hypromellose yakha into efana nejeli lapho ihlangana noketshezi, okungase kubambezele ukuncibilika nokumuncwa kwemithi. Uma uthatha noma yimiphi imithi, okuhlanganisa imithi kadokotela noma imithi etholakala ngaphandle kwekhawunta, kubalulekile ukubonisana nomhlinzeki wakho wokunakekelwa kwezempilo ngaphambi kokuthatha i-hypromellose noma ezinye izithasiselo zokudla.

Isiphetho

I-hypromellose ibhekwa njengephephile ukusetshenziswa yiziphathimandla ezihlukahlukene zokulawula. Isetshenziswa kabanzi njengesengezo sokudla, i-thickener, ne-emulsifier, kanye nesakhi semithi ekukhiqizeni amaphilisi, amaphilisi, kanye namalungiselelo e-ophthalmic.