IHydroxypropyl methylcellulose (HPMC) iyi-polymer eguquguqukayo evame ukusetshenziswa ezimbonini ezahlukahlukene, kufaka phakathi ezemithi, ezokudla, ezokwakha, nezimonyo. Isici esibalulekile sokusetshenziswa kwayo ukuncibilika kwayo kuzincibilikisi ezihlukene, okuhlanganisa ne-isopropyl alcohol (IPA).
I-HPMC ivamise ukuncibilika ezinhlobonhlobo zezincibilikisi, futhi ukunyibilika kwayo kuyahlukahluka kuye ngezinto ezifana nesisindo samangqamuzana, izinga lokushintsha, kanye nezinga lokushisa. I-HPMC inezinga elithile lokuncibilika esimweni se-isopropyl alcohol.
I-Isopropyl alcohol, eyaziwa nangokuthi i-rubbing alcohol, iyisincibilikisi esivamile esisetshenziswa ezinhlobonhlobo zezinhlelo zokusebenza. Yaziwa ngekhono layo lokuncibilikisa inhlobonhlobo yezinto, futhi i-HPMC injalo. Kodwa-ke, ukunyibilika kwe-HPMC ku-isopropyl alcohol kungase kungapheleli noma kube khona manjalo futhi kungase kuncike ezintweni ezimbalwa.
Izinga lokufakwa esikhundleni se-HPMC lisho izinga lokushintshanisa i-hydroxypropyl namaqembu e-methyl kumaqembu e-hydroxyl esakhiweni se-cellulose. Le parameter ithinta ukunyibilika kwe-HPMC kuzinyibilikisi ezihlukene. Ngokuvamile, amazinga aphezulu okushintshana angathuthukisa ukuncibilika kuzincibilikisi ezithile, kuhlanganise ne-isopropyl alcohol.
Isisindo samangqamuzana e-HPMC esinye isici okufanele sicatshangelwe. I-HPMC yesisindo esiphezulu se-molecular ingase ibe nezakhiwo ezihlukene zokuncibilika uma iqhathaniswa nokuhluka okuphansi kwesisindo samangqamuzana. Kuyaqapheleka ukuthi kunamamaki ahlukahlukene e-HPMC emakethe anezakhiwo ezahlukahlukene, futhi abakhiqizi bavame ukunikeza isiqondiso esiqondile mayelana nokuncibilika kwabo kuzincibilikisi ezahlukene.
Izinga lokushisa liphinde libe nomthelela ekuncibilikeni kwe-HPMC ku-isopropyl alcohol. Ngokuvamile, izinga lokushisa elikhulayo lingathuthukisa ukunyibilika kwezinto eziningi, kodwa lokhu kungase kwehluke kuye ngebanga elithile le-polymer.
Ukuncibilikisa i-HPMC ku-isopropyl alcohol, ungalandela lezi zinyathelo ezijwayelekile:
Linganisa inani elidingekayo: Thola inani le-HPMC elidingekayo esicelweni sakho.
Lungiselela i-solvent: Sebenzisa isitsha esifanelekile bese wengeza inani elidingekayo le-isopropyl alcohol. Kunconywa ukusebenzisa isitsha esinesivalo ukuvimbela ukuhwamuka.
Engeza i-HPMC Kancane Kancane: Ngenkathi ugqugquzela noma ugqugquzela isincibilikisi, kancane kancane engeza i-HPMC. Qinisekisa ukuthi uxuba kahle ukuze ukhuthaze ukuhlakazeka.
Lungisa izimo uma kudingeka: Uma ukuhlakazwa okuphelele kungafinyelelwa, cabanga ukulungisa izici ezifana nezinga lokushisa noma ukusebenzisa ibanga elihlukile le-HPMC.
Hlunga uma kunesidingo: kwezinye izimo, izinhlayiya ezingancibiliki zingase zibe khona. Uma ukukhanya kubalulekile, ungakwazi ukuhlunga isixazululo ukuze ususe noma yiziphi izinhlayiya eziqinile ezisele.
I-HPMC ivamise ukuncibilika kutshwala be-isopropyl, kodwa izinga lokuncibilika lithintwa izici ezifana nezinga lokushintsha, isisindo samangqamuzana, nezinga lokushisa. Uma unebanga elithile noma uhlobo lwe-HPMC, kuyanconywa ukuthi uhlole imihlahlandlela yomkhiqizi ukuze uthole ulwazi olunembile mayelana ne-isopropyl alcohol solubility.
Isikhathi sokuthumela: Jan-25-2024