IHypromellose iyi-hydrophilic, i-polymer engeyona i-ionic esetshenziswa ezinhlelweni ezahlukahlukene zemithi nezokwelapha, kufaka phakathi njenge-lubricant kanye ne-viscosity ejenti emathonsini wamehlo, njenge-ejenti enamathela kumaphilisi nama-capsules, nanjenge-ejenti ekhishwa njalo emithini. izinhlelo zokulethwa. Indlela yokusebenza ye-hypromellose ihlobene nezakhiwo zayo eziyingqayizivele ze-physicochemical, okuhlanganisa amandla ayo okubamba amanzi aphezulu kanye nekhono layo lokwenza ama-gel phambi kwamanzi.
- Ukugcotshwa: Endabeni ye-hypromellose eye drops, indlela eyinhloko yokusebenza iwukugcoba. Uma isetshenziswa ebusweni beso, i-hypromellose yakha ifilimu elincanyana elisiza ukunciphisa ukungqubuzana phakathi kwejwabu leso kanye ne-cornea, ngaleyo ndlela kuncishiswe ukoma, ububomvu, nokucasuka. Lo mphumela wokugcoba ungenxa yomthamo ophezulu wokubamba amanzi we-hypromellose, ovumela ukuthi ibambe futhi igcine umswakama ovela efilimu yezinyembezi, kanye nekhono layo lokusabalalisa ngokulinganayo phezu kweso.
- I-Viscosity: I-Hypromellose ingaphinda ikhulise i-viscosity yezixazululo, ezingathuthukisa ukugcinwa kwazo endaweni ye-ocular futhi kwandise isikhathi sabo sokuthintana neso. Lo mphumela ubaluleke kakhulu uma kwenzeka amaconsi esweni, njengoba angasiza ekwandiseni ukusebenza kahle kokwelapha kwemithi.
- I-Coating: I-Hypromellose ivame ukusetshenziswa njenge-ejenti yokugqoka kumaphilisi namaphilisi. Kulolu hlelo lokusebenza, yakha ungqimba oluvikelayo oluzungeze umuthi ongasiza ukulawula izinga lokukhululwa kwezidakamizwa nokuvikela umuthi ekuwohlokeni esiswini noma emathunjini. Indlela yokusebenza ye-hypromellose kulo mongo ihlobene nekhono layo lokwenza umgoqo phakathi komuthi nendawo ezungezile, engasiza ekuthuthukiseni ukuzinza kanye nokuba khona kwe-bioavailability yomuthi.
- Ukukhishwa Okuqhubekayo: I-Hypromellose ingasetshenziswa futhi njenge-ejenti ekhishwa okuqhubekayo ezinhlelweni zokulethwa kwezidakamizwa. Kulolu hlelo lokusebenza, isetshenziselwa ukwakha i-matrix efana nejeli engalawula ukukhishwa komuthi isikhathi eside. Indlela yokusebenza ye-hypromellose kulo mongo ihlobene nekhono layo lokwenza inethiwekhi yamabhondi e-hydrogen angacupha ama-molecule ezidakamizwa futhi alawule ukukhululwa kwawo.
\umshini wokusebenza kwe-hypromellose uhlobene nezici zayo eziyingqayizivele ze-physicochemical, ezihlanganisa amandla ayo okubamba amanzi aphezulu, ikhono layo lokwakha ama-gel phambi kwamanzi, kanye nekhono layo lokwandisa i-viscosity yezixazululo. Lezi zakhiwo ziyenza ibe i-polymer eguquguqukayo futhi esetshenziswa kabanzi embonini yezemithi nezokwelapha, ikakhulukazi ekuthuthukisweni kwamaconsi wamehlo, amaphilisi, amaphilisi, nezinhlelo zokulethwa kwezidakamizwa.
Isikhathi sokuthumela: Mar-04-2023