IHydroxypropyl Methyl Cellulose E15 Yokunamathela Kwethebhulethi

IHydroxypropyl Methyl Cellulose (HPMC) E15 iyinto evamile esetshenziswa njengengcina yethebhulethi embonini yezemithi. Impushana emhlophe noma emhlophe engenaphunga futhi engenambitheki, enezinga eliphezulu lokuhlanzeka. I-HPMC E15 iyi-ether ye-cellulose encibilika emanzini evame ukusetshenziswa njenge-ejenti yokwakha ifilimu, i-thickener, stabilizer, kanye ne-emulsifier ezinhlotsheni zezinhlelo zokusebenza.

I-HPMC E15 isetshenziswa kakhulu njengesinamathiseli sethebhulethi ngenxa yokuthi inezinto zokunamathela ezinhle kakhulu, ihambisana nohlu olubanzi lwezinye izinto ezisizayo, futhi inobuthi obuphansi. Futhi ayiyona i-ionic, okusho ukuthi ayifaki ioni emanzini ngakho-ke mancane amathuba okuthi ihlangane nezinye izithako.

Izakhiwo zokunamathela ze-HPMC E15 zibangelwa ikhono layo lokwenza ifilimu eqinile lapho ihlangana namanzi. Le filimu iyakwazi ukuhlanganisa izendlalelo ezihlukene zethebhulethi, idale ithebulethi eqinile nefanayo ekwazi ukumelana nokuphuka nokuqhekeka.

Ngaphezu kwezakhiwo zayo zokunamathisela, i-HPMC E15 iphinde isetshenziswe njenge-disintegrant yethebhulethi. Lokhu kusho ukuthi kusiza ithebhulethi ukuba ihlehlise futhi incibilike esiswini, okuvumela izithako ezisebenzayo ukuthi zingene egazini.

Uma isetshenziswa njenge-adhesive tablet, i-HPMC E15 ivamise ukuxutshwa nezinye izinto ezisizayo njenge-lactose, i-microcrystalline cellulose, nesitashi sombila. Ukwakhiwa okuqondile kuzoncika ezidingweni ezithile zethebhulethi, njengosayizi wayo, umumo, nezithako ezisebenzayo eziqukethwe.

I-HPMC E15 iphinda isetshenziswe kwezinye izinhlelo zokusebenza zemithi njengasekwenziweni kokukhishwa okulawulwayo, lapho ingasetshenziswa khona ukuguqula izinga lokukhishwa lesithako esisebenzayo. Ibuye isetshenziswe njenge-binder, stabilizer, kanye ne-thickener kumakhilimu, amafutha okugcoba, namajeli.

Sekukonke, i-HPMC E15 iwumsebenzi oguquguqukayo futhi owusizo ovame ukusetshenziswa embonini yezemithi njengento enamathelayo yethebhulethi. Izakhiwo zayo zokunamathela ezinhle kakhulu, ubuthi obuphansi, nokuhambisana nezinhlobonhlobo zezinto ezisizayo kuyenza ibe inketho ekahle yokudala amaphilisi aqinile nafanayo.