IHydroxypropylcellulose (HEC) iphuma ku-cellulose, i-polymer yemvelo etholakala ezindongeni zamaseli ezitshalo. I-HPC isetshenziswa kakhulu ezimbonini ezehlukene njengezemithi, izimonyo nezimboni zokudla ngenxa yezakhiwo zayo ezinhle kakhulu zokwakha amafilimu nokujiya. Ukuhlanganiswa kwe-hydroxypropylcellulose kuhilela izinyathelo eziningi futhi inqubo ingaba yinkimbinkimbi.
Isingeniso se-hydroxypropylcellulose:
1. Ukusebenzisa i-cellulose njengento yokuqala:
Imithombo eyinhloko ye-cellulose yizinto zezitshalo ezifana ne-pulp yokhuni noma ukotini. I-Cellulose iyi-polymer eqondile eyakhiwe amayunithi e-glucose axhunywe ngamabhondi e-β-1,4-glycosidic. Inezinga eliphezulu le-polymerization, nezinkulungwane zamayunithi e-glucose akha amaketanga amade.
2. Ukusabela kwe-Etherification:
Ukuhlanganiswa kwe-hydroxypropylcellulose kuhilela ukwethulwa kwamaqembu e-hydroxypropyl kumgogodla we-cellulose nge-etherification. Lokhu kusabela ngokuvamile kuhilela ukusetshenziswa kwe-propylene oxide njenge-alkylating agent.
I-Cellulose + propylene oxide → i-alkali-catalyzed hydroxypropyl cellulose + by-product cellulose + propylene oxide alkali-catalyzed hydroxypropyl cellulose + by-by-product
Isisekelo se-catalysis sibalulekile ukukhuthaza ukusabela phakathi kwamaqembu e-cellulose hydroxyl ne-propylene oxide. Lesi sinyathelo ngokuvamile senziwa ngaphansi kwezimo ezilawulwayo ukuze kuqinisekiswe izinga elifiswayo lokushintshwa (DS) lamaqembu e-hydroxypropyl ochungechungeni lwe-cellulose.
3. IHydroxypropylation:
I-Hydroxypropylation ihlanganisa ukufakwa kwamaqembu e-hydroxypropyl kumgogodla we-cellulose. Lokhu kuguqulwa kunikeza ukuncibilika okuthuthukisiwe nezinye izinto ezifiselekayo ku-polymer cellulosic. Izimo zokusabela, okuhlanganisa izinga lokushisa, ingcindezi kanye nesikhathi sokusabela, zilawulwa ngokucophelela ukuze kuzuzwe izici zomkhiqizo ezifiselekayo.
4. Ukwelashwa kwe-alkali:
Ngemuva kwe-hydroxypropylation, ukwelashwa kwe-alkaline kuvame ukusetshenziselwa ukunciphisa noma yikuphi ukungcola okune-asidi okusele futhi kulungiswe i-pH yengxube yokusabela. Lesi sinyathelo sibalulekile enqubweni yokuhlanza elandelayo.
5. Izinyathelo zokuhlanza:
Ngemva kokusabela kwe-etherification, izinyathelo ezimbalwa zokuhlanza ngokuvamile ziyenziwa ukuze kutholwe i-high-purity hydroxypropylcellulose. Lezi zinyathelo zingabandakanya:
Geza: Geza ingxube yokusabela ukuze ususe ama-reagents asele, imikhiqizo kanye ne-cellulose engaphenduliwe.
Ukuhlunga: Ukuhlunga kusetshenziselwa ukuhlukanisa ukungcola okuqinile kungxube yokusabela.
Ukomisa: I-hydroxypropyl cellulose emanzi bese yomiswa ukuze kususwe noma yimuphi umswakama osele.
6. Ukulawula isisindo samangqamuzana:
Isisindo samangqamuzana e-hydroxypropylcellulose singalawulwa ngesikhathi sokuhlanganiswa ukuze sivumelanise izakhiwo zayo nezinhlelo zokusebenza ezithile. Lokhu kufinyelelwa ngokulungisa izimo zokusabela, njengenani lama-reagents nesikhathi sokuphendula.
Ukukhiqizwa kwezimboni:
1. Inqubo yesikhashana noma eqhubekayo:
Ukukhiqizwa kwe-hydroxypropyl cellulose kungenziwa nge-batch noma izinqubo eziqhubekayo. Inqubo yeqoqo ifanele ukukhiqizwa kwezinga elincane, kuyilapho inqubo eqhubekayo ifaneleka kakhulu ekukhiqizeni ngezinga elikhulu.
2. Ukulawulwa kwekhwalithi:
Izinyathelo zokulawula ikhwalithi zisetshenziswa kuzo zonke izigaba zenqubo yokukhiqiza ukuze kuqinisekiswe ukuhambisana nokuhlanzeka komkhiqizo wokugcina. Amasu okuhlaziya afana ne-chromatography, i-spectroscopy kanye nezifundo ze-rheological zisetshenziselwa ukuhlola amapharamitha abalulekile njengezinga lokushintshwa, isisindo samangqamuzana kanye nokuhlanzeka.
Ukusetshenziswa kwe-Hydroxypropyl Cellulose:
1. Imboni yezemithi:
IHydroxypropylcellulose isetshenziswa kabanzi emalungiselelweni emithi njenge-binder, i-disintegrant kanye ne-ejenti yokukhululwa elawulwayo. Ukuhambisana kwayo nohlu olubanzi lwezidakamizwa kanye nokungabi namandla kwayo kuyenza ibe isakhi esiguquguqukayo.
2. Imboni yezimonyo:
Embonini yezimonyo, i-hydroxypropylcellulose isetshenziswa ekwakhiweni kwemikhiqizo yokunakekelwa kwezinwele, okhilimu besikhumba neminye imikhiqizo yokunakekela umuntu. Izakhiwo zayo zokwenza ifilimu ziyenza ibe yigugu emikhiqizweni yokunakekelwa kwezinwele.
3. Imboni yokudla:
Embonini yokudla, i-hydroxypropylcellulose isetshenziswa njenge-thickener kanye ne-gelling agent. Itholakala ekudleni okuhlukahlukene futhi isiza ukuthuthukisa ukuthungwa nokuzinza kwazo.
Ukuhlanganiswa kwe-hydroxypropylcellulose kuhilela ukufakwa kwe-cellulose ngokufaka amaqembu e-hydroxypropyl. Ukusabela kuvame ukwenziwa isisekelo, kulandelwe izinyathelo zokuhlanza ukuze kutholwe umkhiqizo omsulwa kakhulu. Ukukhiqizwa kwezimboni kungenziwa nge-batch noma izinqubo eziqhubekayo ezinezinyathelo eziqinile zokulawula ikhwalithi. IHydroxypropylcellulose inohlu olubanzi lwezicelo embonini yezemithi, yezimonyo neyokudla ngenxa yezakhiwo zayo eziyingqayizivele kanye nokuhlukahluka. Ukuthuthukiswa okuqhubekayo kwezinqubo zokukhiqiza kanye nokuthuthukiswa kwezinhlelo zokusebenza ezintsha kugcizelela
Isikhathi sokuthumela: Dec-26-2023