Focus on Cellulose ethers

Izinzuzo ze-Pharmaceutical Grade HPMC

Izinzuzo ze-Pharmaceutical Grade HPMC

 

I-HPMC isibe ngomunye wabasizi bemithi abasetshenziswa kakhulu ekhaya naphesheya, ngoba i-HPMC inezinzuzo ezinye izihlanganisi ezingenazo.

1. Ukuncibilika kwamanzi

Incibilika emanzini abandayo angaphansi kuka-40°C noma ku-70% i-ethanol, ngokuyisisekelo ayincibiliki emanzini ashisayo angaphezu kuka-60°C, kodwa iyakwazi ukwenza ijeli.

2. Ukungabi namandla kwamakhemikhali

I-HPMC iwuhlobo lwe-non-ionici-cellulose ether. Isixazululo saso asinakho ukushaja kwe-ionic futhi asihlanganyeli nosawoti wensimbi noma izinhlanganisela eziphilayo ze-ionic. Ngakho-ke, amanye ama-excipients awaphenduli nawo phakathi nenqubo yokulungiselela.

3. Ukuzinza

Iqinile ku-asidi ne-alkali, futhi ingagcinwa isikhathi eside phakathi kwe-pH 3 kanye ne-11 ngaphandle koshintsho olusobala ku-viscosity. Isixazululo esinamanzi se-HPMC sinomphumela wokunqanda isikhutha futhi singagcina ukuqina kwe-viscosity ngesikhathi sokugcina isikhathi eside. Ukuzinza kwekhwalithi yemithi esebenzisa i-HPMC njengezithambisi zokulungiselela kungcono kunaleyo yemithi esebenzisa izithasiselo zendabuko (njenge-dextrin, isitashi, njll.).

4. I-viscosity eguquguqukayo

I-viscosity derivatives ehlukene ye-HPMC ingaxutshwa ngokuvumelana nezilinganiso ezahlukene, futhi i-viscosity yayo ingashintsha ngokuvumelana nemithetho ethile, futhi inobudlelwane obuhle bomugqa, ngakho-ke isilinganiso singakhethwa ngokuvumelana nezidingo. 2.5 I-HPMC ene-metabolism inert ayimuncwa noma igaywe emzimbeni, futhi ayinikezi ukushisa, ngakho-ke iyisisetshenziswa esiphephile sokulungiswa kwemithi. .

5. Ezokuphepha

I-HPMC ngokuvamile ithathwa njengento engenabuthi nengacasuli.

 


Isikhathi sokuthumela: Jan-27-2023
Ingxoxo ye-WhatsApp Online!