Yintoni indlela yokusebenza ye-HPMC?

I-HPMC, okanye i-hydroxypropyl methylcellulose, i-synthetic, i-polymer enyibilikayo emanzini ephuma kwi-cellulose. Isetyenziswa kwizicelo ezahlukeneyo, kubandakanya ukutya, amayeza, izinto zokuthambisa, kunye neemveliso zoshishino. I-HPMC yi-non-ionic, i-viscosity-enhancing polymer enokuthi isetyenziswe ukujiya, ukuzinzisa, kunye nokumisa uluhlu olubanzi lwezithako.

Indlela yokusebenza ye-HPMC isekelwe ekukwazini ukwenza iibhondi ze-hydrogen kunye neemolekyuli zamanzi, ukudala uthungelwano lwamandla e-intermolecular. Le nethiwekhi yeebhondi ze-hydrogen yenza i-matrix ene-dimensional-dimensional enokuthi ibambe kwaye ibambe iimolekyuli zamanzi. Le matrix inoxanduva lweempawu zokuphucula i-viscosity ye-HPMC, kunye nokukwazi kwayo ukumisa kunye nokuzinzisa izithako.

I-HPMC nayo inobudlelwane obuphezulu be-lipids, obuvumela ukuba yenze umqobo okhuselayo malunga nezithako ezisekelwe kwioli. Lo mqobo unceda ukukhusela izithako ezisekelwe kwioli ekuhlukaneni nesigaba samanzi, ngaloo ndlela ukwandisa ukuzinza kokuqulunqwa. Ukongezelela, umqobo okhuselayo owenziwe yi-HPMC unceda ukunciphisa izinga lokunyuka kwe-evaporation yezithako ezisekelwe kwioli, ezinokukunceda ukwandisa ixesha leshelufu lokuqulunqwa.

Okokugqibela, i-HPMC inokusebenza njenge-surfactant, enceda ekunciphiseni ukuxinana komphezulu wezisombululo ezinamanzi. Oku kunokunceda ukuphucula ukumanzisa kunye nokusabalalisa izithako, ezinokuphucula ukuzinza kunye nokusebenza kokuqulunqwa.

Isishwankathelo, indlela yokusebenza ye-HPMC isekelwe kwisakhono sayo sokwenza iibhondi ze-hydrogen kunye neemolekyuli zamanzi, ukudala inethiwekhi ye-intermolecular forces enokuthi ibambe kwaye ibambe iimolekyuli zamanzi. Olu nxibelelwano lweebhondi ze-hydrogen luxanduva lweempawu zokuphucula i-viscosity ye-HPMC, kunye nokukwazi kwayo ukunqumamisa nokuzinzisa izithako. Ukongeza, i-HPMC inobudlelwane obuphezulu be-lipids, obuvumela ukuba yenze umqobo okhuselayo ojikeleze izithako ezisekwe kwi-oyile. Okokugqibela, i-HPMC inokusebenza njenge-surfactant, enceda ekunciphiseni ukuxinana komphezulu wezisombululo ezinamanzi. Zonke ezi zakhiwo zenza i-HPMC ibe sisithako esisebenzayo nesisebenzayo kuluhlu olubanzi lwezicelo.