I-Methyl cellulose (MC) kunye ne-hydroxypropyl methyl cellulose (HPMC) zimbini ze-cellulose derivatives ezisetyenziswa ngokubanzi kumashishini, ukwakhiwa, amayeza, ukutya kunye nezinye iindawo. Nangona zifana nesakhiwo, zineepropati ezahlukeneyo kwaye Kukho ukungafani okuphawulekayo kwizicelo kunye neenkqubo zokuvelisa.
1. Umahluko kwisakhiwo sekhemikhali
I-Methylcellulose (MC) kunye ne-hydroxypropylmethylcellulose (HPMC) zombini ziphuma kwi-cellulose yendalo kwaye ziyi-chemically modified cellulose ether compounds. Kodwa umahluko wabo ikakhulu ulele kudidi kunye nenani lamaqela abambeleyo.
I-Methyl cellulose (MC)
I-MC iveliswa ngokutshintshela amaqela e-hydroxyl kwi-cellulose kunye namaqela e-methyl (okt -OCH₃). Ubume bekhemikhali be-MC ikakhulu bubandakanya amaqela athatha indawo ye-methyl kwikhonkco eliphambili leselulosi, kwaye izinga lokutshintsha lichaphazela ukunyibilika kwayo kunye neempawu. I-MC iqhele ukunyibilika emanzini abandayo kodwa hayi emanzini ashushu.
IHydroxypropyl methylcellulose (HPMC)
I-HPMC iphinda iguqulwe ngesiseko se-methylcellulose, ngokutshintsha inxalenye yamaqela e-hydroxyl nge-methyl (-CH₃) kunye ne-hydroxypropyl (-CH₂CH (OH)CH₃). Xa kuthelekiswa ne-MC, i-molecular structure ye-HPMC inzima ngakumbi, i-hydrophilicity yayo kunye ne-hydrophobicity ilungelelene kakuhle, kwaye inokunyibilika emanzini abandayo kunye nashushu.
2. Umahluko kwi-solubility yomzimba kunye neekhemikhali
I-MC: I-Methylcellulose ngokubanzi ine-solubility efanelekileyo emanzini abandayo, kodwa iya kwenza ijeli xa ubushushu buphakama. Emanzini ashushu, i-MC ayinyibiliki, yenze ijeli ye-thermal.
I-HPMC: I-Hydroxypropyl methylcellulose inokunyibilika ngokufanayo kumanzi abandayo nashushu, inoluhlu olubanzi lweqondo lokushisa lokunyibilika, kwaye ukunyibilika kwayo kuzinzile kune-MC.
I-Thermal gelability
I-MC: I-MC ineempawu eziqinileyo ze-thermal gelling. Xa izinga lokushisa liphakama kwinqanaba elithile, liya kwenza i-gel kwaye lilahlekelwe yi-solubility yayo. Olu phawu lwenza ukuba lusetyenziswe ngokukhethekileyo kumashishini okwakha kunye namayeza.
HPMC: HPMC kwakhona iipropati ezithile thermal gelling, kodwa ijeli yayo ubushushu ukwakheka iphezulu kwaye isantya ijeli ukwakheka iyacotha. Xa kuthelekiswa ne-MC, iipropathi zejeli ze-HPMC ziyakwazi ukulawuleka kwaye ngenxa yoko zinenzuzo ngakumbi kwizicelo ezifuna uzinzo oluphezulu lobushushu.
Umsebenzi womphezulu
I-MC: I-MC inomsebenzi ophantsi womphezulu. Nangona inokusetyenziswa njenge-emulsifier ethile okanye i-thickener kwezinye izicelo, umphumo awubalulekanga njenge-HPMC.
I-HPMC: I-HPMC inomsebenzi owomeleleyo womphezulu, ngakumbi ukuqaliswa kweqela le-hydroxypropyl, eyenza kube lula ukumilisela, ukunqumamisa kunye nokujiya kwisisombululo. Ngoko ke, isetyenziswa ngokubanzi njengesongezo kwiingubo kunye nezinto zokwakha.
Ukunyamezela ityuwa kunye nokuzinza kwe-pH
I-MC: I-Methylcellulose inonyamezelo olubi lwetyuwa kwaye ithanda ukuba nemvula kwiindawo ezinetyuwa eninzi. Inozinzo olubi kwiindawo ze-asidi kunye ne-alkali kwaye ichaphazeleka lula ngexabiso le-pH.
I-HPMC: Ngenxa yobukho be-hydroxypropyl substituent, i-HPMC yokunyamezela ityuwa ingcono kakhulu kune-MC, kwaye inokugcina ukunyibilika okulungileyo kunye nozinzo kuluhlu olubanzi lwe-pH, ngoko ifanelekile kwiindawo ezahlukeneyo zeekhemikhali.
3. Umahluko kwiinkqubo zemveliso
Ukuveliswa kwe-MC
I-Methylcellulose iveliswa nge-methylation reaction ye-cellulose, ngokuqhelekileyo isebenzisa i-methyl chloride ukusabela nge-alkaline cellulose ukuze ithathe indawo yamaqela e-hydroxyl kwii-molecule ze-cellulose. Le nkqubo idinga ulawulo lweemeko zokusabela ukuze kuqinisekiswe iqondo elifanelekileyo lokutshintshwa, elichaphazela ukunyibilika kunye nezinye iimpawu ze-physicochemical zemveliso yokugqibela.
Ukuveliswa kweHPMC
Ukuveliswa kwe-HPMC kusekelwe kwi-methylation kwaye yongeza impendulo ye-hydroxypropylation. Oko kukuthi, emva kokuphendula kwe-methylation ye-methyl chloride, ipropylene oxide iphendula kunye neselulosi ukuvelisa i-hydroxypropyl substituent. Ukuqaliswa kweqela le-hydroxypropyl kuphucula ukunyibilika kunye namandla okuhambisa amanzi e-HPMC, eyenza inkqubo yayo yokuvelisa ibe nzima ngakumbi kunye neendleko eziphezulu kancinci kune-MC.
4. Umahluko kwiinkalo zesicelo
Intsimi yezinto zokwakha
I-MC: I-MC isetyenziswa rhoqo kwizinto zokwakha, ngakumbi njenge-thickener, i-agent egcina amanzi kunye ne-adhesive kudaka olomileyo kunye ne-putty powder. Nangona kunjalo, ngenxa yeempawu zayo ze-thermal gelling, i-MC inokusilela kwiindawo ezinobushushu obuphezulu.
I-HPMC: I-HPMC isetyenziswa ngokubanzi kwindawo yokwakha. Ngenxa yokuba nayo inozinzo olufanelekileyo kwiindawo eziphakamileyo zokushisa, ifaneleka ngakumbi kwiimeko ezifuna ukunyamezela ubushushu obuphezulu, njengezinto zokuncamathelisa iithayile, i-insulation mortars kunye ne-self-leveling floors. .
Amasimi amayeza kunye nokutya
MC: I-Methylcellulose isetyenziswa ngokuqhelekileyo njenge-disintegrant kunye ne-thickener kwiipilisi kumalungiselelo amayeza. Ikwasetyenziswa kokunye ukutya njenge-thickener kunye nefiber supplement.
I-HPMC: I-HPMC ineenzuzo ezininzi kwicandelo lamayeza. Ngenxa yokunyibilika kwayo okuzinzile kunye nokuhambelana kakuhle kwe-biocompatibility, isoloko isetyenziswa kwizixhobo zefilimu ezizinzileyo kunye namaqokobhe e-capsule amachiza. Ukongeza, i-HPMC ikwasetyenziswa ngokubanzi kushishino lokutya, ngakumbi xa kusenziwa ii-capsules zemifuno.
Icandelo leengubo kunye neepeyinti
I-MC: I-MC ineempembelelo ezingcono zokutyeba kunye nokwenza ifilimu, kodwa ukuzinza kwayo kunye nokukwazi ukulungiswa kwe-viscosity kwisisombululo akulunganga njenge-HPMC.
I-HPMC: I-HPMC isetyenziswa ngokubanzi kwishishini lepeyinti kunye nepeyinti ngenxa yokuqina kwayo okugqwesileyo, i-emulsification kunye neempawu zokwenza ifilimu, ngakumbi njengesixhobo esityebileyo kunye ne-ejenti yokulinganisa kwiingubo ezisekwe emanzini, ezinokuphucula kakhulu ukusebenza kolwakhiwo kunye nomphezulu wokugquma. . Isiphumo.
5. Ukhuseleko lokusingqongileyo kunye nokhuseleko
Zombini i-MC kunye ne-HPMC zilungisiwe kwi-cellulose yendalo kwaye zine-biodegradability elungileyo kunye neempawu zokhuseleko lokusingqongileyo. Zomibini azinabungozi kwaye zingenabungozi ekusebenziseni kwaye zithobela iimfuno zokusingqongileyo, ngoko ke zikhuselekile kakhulu ukuba zisetyenziswe kwiindawo zokutya, amayeza kunye nezithambiso.
Nangona i-methylcellulose (MC) kunye ne-hydroxypropylmethylcellulose (HPMC) zifana nokwakhiwa kweekhemikhali, ngenxa yamaqela ahlukeneyo athatha indawo, ukunyibilika kwabo, ukuguquguquka kwe-thermal, umsebenzi ongaphezulu, inkqubo yokuvelisa kunye nokusetyenziswa kwahlukileyo. Kukho umahluko ocacileyo kwiinkalo kunye neminye imiba. I-MC ifanelekile kwiimeko eziphantsi zobushushu kunye nokuqina okulula kunye neemfuno zokugcinwa kwamanzi, ngelixa i-HPMC ifaneleka ngakumbi kumashishini anzima, amayeza kunye nezicelo zokwakha ngenxa yokunyibilika kwayo okulungileyo kunye nokuzinza kwe-thermal.
Ixesha lokuposa: Oct-25-2024