Yintoni umahluko phakathi kwe-HPMC E kunye ne-K?

I-HPMC (i-Hydroxypropyl Methylcellulose) luhlobo lwe-ether ye-cellulose esetyenziswa kwizicelo ezahlukeneyo, kubandakanywa amayeza, ukutya, izimonyo kunye nokwakhiwa. I-HPMC yi-non-ionic, i-polymer enyibilikayo emanzini ephuma kwi-cellulose, kwaye ifumaneka kwiindidi ezimbini: i-HPMC E kunye ne-HPMC K.

I-HPMC E libakala elisezantsi-viscosity le-HPMC, kwaye isetyenziswa ngokuyintloko kwizicelo zamayeza. Isetyenziswa njenge-binder, i-disintegrant, kunye ne-arhente yokumisa kwiipilisi, ii-capsules, kunye neegranules. Ikwasetyenziswa njengesixhobo sokujiya kwiisyrups, iikhrimu, kunye nezithambiso. I-HPMC E yibakala eliphantsi-i-viscosity, oku kuthetha ukuba ine-viscosity ephantsi xa inyibilika emanzini. Oku kwenza kube yinto efanelekileyo yokusetyenziswa kwizicelo zamachiza, njengoko kulula ukuxuba kunye nokusabalalisa emanzini.

I-HPMC K yibakala eliphezulu le-viscosity ye-HPMC, kwaye isetyenziswa ikakhulu kulwakhiwo kunye nezicelo zokutya. Isetyenziswa njengesibophelelo, isingqimba, kunye nearhente yokuxhoma kwizinto zokwakha, ezifana nokuncamathelisa iithayile, iigrouts, kunye neplastikhi. Ikwasetyenziswa njengesixhobo sokujiya kwiimveliso zokutya, ezifana nejem, iijeli, neesosi. I-HPMC K yibakala eliphezulu le-viscosity, oku kuthetha ukuba ine-viscosity ephezulu xa inyibilika emanzini. Oku kuyenza ilungele ukusetyenziswa kulwakhiwo kunye nezicelo zokutya, njengoko ikwazi ukubonelela ngokuqina, ukuhambelana kwe-viscous.

Umahluko ophambili phakathi kwe-HPMC E kunye ne-HPMC K yi-viscosity. I-HPMC E yibakala eliphantsi-i-viscosity, oku kuthetha ukuba ine-viscosity ephantsi xa inyibilika emanzini. Oku kwenza kube yinto efanelekileyo yokusetyenziswa kwizicelo zamachiza, njengoko kulula ukuxuba kunye nokusabalalisa emanzini. I-HPMC K yibakala eliphezulu le-viscosity, oku kuthetha ukuba ine-viscosity ephezulu xa inyibilika emanzini. Oku kuyenza ilungele ukusetyenziswa kulwakhiwo kunye nezicelo zokutya, njengoko ikwazi ukubonelela ngokuqina, ukuhambelana kwe-viscous.

Ukongeza kwi-viscosity, i-HPMC E kunye ne-HPMC K nazo zihluke ngokumalunga nokwakheka kweekhemikhali. I-HPMC E inobunzima obuphantsi bemolekyuli kune-HPMC K, enika i-viscosity ephantsi. I-HPMC K inobunzima obuphezulu bemolekyuli, obunika i-viscosity ephezulu.

Okokugqibela, i-HPMC E kunye ne-HPMC K nazo ziyahluka ngokokunyibilika kwazo. I-HPMC E iyanyibilika emanzini abandayo, ngelixa i-HPMC K inyibilika emanzini ashushu. Oku kwenza i-HPMC E ilungele ukusetyenziswa kwizicelo zamachiza, njengoko inokuxutywa ngokulula kwaye isasazwe emanzini abandayo. I-HPMC K ilungele ukusetyenziswa kulwakhiwo kunye nezicelo zokutya, njengoko inokuxutywa ngokulula kwaye isasazwe kumanzi ashushu.

Ukuqukumbela, umahluko omkhulu phakathi kwe-HPMC E kunye ne-HPMC K yi-viscosity. I-HPMC E yibakala eliphantsi-i-viscosity, ngelixa i-HPMC K ibakala eliphezulu le-viscosity. Ukongeza, HPMC E has a ubunzima molekyuli esezantsi HPMC K, kwaye inyibilika emanzini abandayo, lo gama HPMC K inyibilika emanzini ashushu. Le yantlukwano yenza i-HPMC E kunye ne-HPMC K ilungele ukusetyenziswa kwizicelo ezahlukeneyo.