Yintoni iHydroxypropylMethylCellulose

IHydroxypropyl Methylcellulose (HPMC) yi-ether ye-cellulose engeyiyo ionic ephuma kwi-cellulose yendalo. Idityaniswa ngokuguqulwa kweekhemikhali zeselulosi, efumaneka kwintlama yomthi okanye imicu yomqhaphu. I-HPMC isetyenziswa ngokubanzi kumashishini ahlukeneyo ngenxa yeepropati zayo eziguquguqukayo kunye nokusetyenziswa.

Ulwakhiwo lweMichiza:

• I-HPMC ine-cellulose backbone ene-hydroxypropyl kunye ne-methyl substituents eqhotyoshelwe kumaqela e-hydroxyl yeeyunithi ze-glucose. Iqondo lokuthatha indawo (DS) libonisa umndilili wenani le-hydroxypropyl kunye namaqela e-methyl ngeyunithi yeglucose kwikhonkco leselulosi. Ubume bemichiza ye-HPMC inika iipropati ezizodwa ezifana nokunyibilika kwamanzi, amandla okwenza ifilimu, kunye nokuguqulwa kwe-viscosity.

Iinkcazelo ngeempawu kunye neempawu:

1. Ukunyibilika kwamanzi: I-HPMC iyanyibilika emanzini abandayo, amanzi ashushu, kunye nezinye izinyibilikisi eziphilayo ezifana ne-methanol kunye ne-ethanol. Ukunyibilika kuxhomekeke kwizinto ezifana neqondo lokutshintshwa, ubunzima bemolekyuli, kunye nobushushu.
2. Ukulawulwa kweViscosity: Izisombululo ze-HPMC zibonisa i-pseudoplastic okanye i-shear-thinning behavior, apho i-viscosity iyancipha ngokunyuka kwesantya sokucheba. Isetyenziswa ngokubanzi njenge-thickener, i-rheology modifier, kunye ne-stabilizer kwiifom ezahlukeneyo zokulawula i-viscosity kunye nokuphucula ukuthungwa.
3. Ukwenziwa kwefilimu: I-HPMC inokwenza iifilimu ezingafihliyo okanye eziguquguqukayo xa zomiswe. Ezi bhanyabhanya zinokubambelela okuhle, ukuguquguquka, kunye neempawu zokuthintelwa, okwenza i-HPMC ilungele ukugquma, iifilimu, kunye neetafile zamachiza.
4. I-Hydration kunye nokuDumba: I-HPMC inobudlelwane obuphezulu bamanzi kwaye inokufunxa kwaye igcine izixa ezikhulu zokufuma. Xa ihlakazekile emanzini, i-HPMC i-hydrates ukwenza iigels ezineempawu zokuhamba kwe-pseudoplastic, ukuphucula ukugcinwa kwamanzi kunye nokusebenza kwimiqulu.
5. Ukungazinzi kweMichiza: I-HPMC ayisebenzi ngokwekhemikhali kwaye ayihlangani neekhemikhali ezibalulekileyo phantsi kweemeko eziqhelekileyo zokusetyenzwa kunye nokugcinwa. Iyahambelana noluhlu olubanzi lwezinye izithako kunye nezongezo ezisetyenziselwa ukwakheka.

Usetyenziso:

• I-Pharmaceuticals: I-excipient kwiipilisi, ii-capsules, i-ointments, i-suspension, kunye ne-conductible-release formulations.
• Ukwakhiwa: Ukongezwa kwi-adhesives ye-tile, i-mortars, i-renders, i-plasters, kunye ne-self-leveling compounds ukuphucula ukugcinwa kwamanzi, ukusebenza kunye nokubambelela.
• Iipeyinti kunye neeNgqungquthela: I-Thickener, i-stabilizer, kunye ne-agent-forming agent kwiipende ze-latex, i-emulsion polymerization, kunye neengubo zokulawula i-viscosity kunye nokuphucula iimpawu zefilimu.
• Ukutya kunye neZiselo: I-ejenti yokuqinisa, i-emulsifier, kunye ne-stabilizer kwiisosi, iingubo, iisuphu, iidizathi, kunye neziselo ukuphucula ukuthungwa kunye nokuzinza.
• Ukhathalelo loBuntu kunye neZithambiso: I-Thickener, i-ejenti yokumisa, kunye ne-ejenti yokwenza ifilimu kwiishampu, ii-conditioners, iikhrimu, ii-lotions, kunye neemaski zokuphucula ukusebenza kwemveliso kunye nobuhle.

IHydroxypropyl Methylcellulose (HPMC) ixatyiswe ngenxa yokuguquguquka kwayo, ukhuseleko, kunye nokusebenza ngempumelelo kwimizi-mveliso eyahlukeneyo, inegalelo ekusetyenzisweni kwayo ngokubanzi kumashishini amaninzi.