Yenziwe ngantoni ihydroxypropylcellulose?

IHydroxypropylcellulose (HPC) iphuma kwi-synthetic ye-cellulose, i-polymer yendalo efumaneka kwiindonga zeeseli zezityalo. Ukuveliswa kwe-hydroxypropylcellulose kubandakanya ukuguqulwa kweekhemikhali zeselulosi ngokusebenzisa uluhlu lweempendulo. Olu hlengahlengiso lunika iipropathi ezithile zeselulosi ezenza kube luncedo kwiintlobo ngeentlobo zezicelo zoshishino kunye nezamayeza.

Ubume be-hydroxypropylcellulose:

I-Hydroxypropylcellulose yi-hydroxyalkyl derivative ye-cellulose apho iqela le-hydroxypropyl lifakwe kwi-cellulose backbone. I-backbone ye-cellulose ngokwayo ikhonkco edibeneyo yeeyunithi ze-glucose ezidityaniswe yi-β-1,4-glycosidic bonds. Amaqela e-Hydroxypropyl aziswa ngokusabela kwi-cellulose nge-propylene oxide phambi kwe-alkaline catalyst.

I-degree of substitution (DS) yiparameter ephambili echaza isakhiwo se-hydroxypropylcellulose. Imele inani eliqhelekileyo lamaqela e-hydroxypropyl kwiyunithi nganye ye-glucose kwikhonkco le-cellulose. I-DS inokulawulwa ngexesha lenkqubo yokudibanisa, evumela ukuveliswa kwe-hydroxypropylcellulose ngamaqondo ahlukeneyo okutshintshwa ukuhlangabezana neemfuno ezithile zesicelo.

Ukwenziwa kwe-hydroxypropylcellulose:

Ukwenziwa kwe-hydroxypropylcellulose kubandakanya ukusabela phakathi kweselulosi kunye nepropylene oxide. Le mpendulo idla ngokuqhutywa phambi kwe-catalyst esisiseko njenge-sodium hydroxide. I-alkaline catalysts ikhuthaza ukuvulwa kwendandatho ye-epoxy kwi-propylene oxide, okubangelwa ukongezwa kwamaqela e-hydroxypropyl kwikhonkco le-cellulose.

Ukusabela ngokuqhelekileyo kuqhutyelwa kwi-solvent kwaye iqondo lokushisa kunye nexesha lokuphendula lilawulwa ngononophelo ukufezekisa iqondo elifunekayo lokutshintsha. Emva kokusabela, imveliso ihlanjululwa ngeenkqubo ezinjengokuhlamba kunye nokucoca ukususa naziphi na ii-reagents ezingaphendulwanga okanye iimveliso.

Iimpawu zeHydroxypropyl Cellulose:

Ukunyibilika: IHydroxypropylcellulose inyibilika kwiintlobo ngeentlobo zezinyibilikisi, kubandakanywa amanzi, i-ethanol, kunye nezinyibilikisi ezininzi eziphilayo. Le propati ye-solubility yenza ukuba ifaneleke kwiintlobo ezahlukeneyo zezicelo.

I-Viscosity: Ukongeza amaqela e-hydroxypropyl kwi-cellulose kwandisa ukunyibilika kunye nokutshintsha iimpawu ze-viscosity ze-polymer. Oku kwenza i-hydroxypropylcellulose ixabiseke kwimixube yoxubo, rhoqo njenge-ejenti yokujiya okanye i-gelling.

Ukuqulunqwa kwefilimu: I-Hydroxypropylcellulose ingenza iifilimu eziguquguqukayo kunye nezicacileyo, zenze ukuba zilungele ukugquma, iifilimu kunye ne-binder kwi-tablet formulations.

Ukuzinza kweThermal: I-Hydroxypropylcellulose inozinzo oluhle lwe-thermal, evumela ukuba isetyenziswe kwiinkqubo ezahlukeneyo zoshishino ngaphandle kokuthotywa okukhulu.

Ukuhambelana: Iyahambelana nezinye iindidi ze-polymers kunye nabancedisi, ukuphucula ukusebenziseka kwayo kwi-pharmaceutical formulations kunye ne-cosmetic formulations.

Ukusetyenziswa kweSelulosi yeHydroxypropyl:

I-Pharmaceuticals: I-Hydroxypropylcellulose isetyenziswa ngokubanzi kwishishini lamachiza njenge-binder kwi-tablet formulations, i-viscosity modifier kwiifom ze-dosage ye-liquid, kunye ne-agent eyenza ifilimu kwi-coatings kwiifom zedosi yomlomo.

IiMveliso zoMntu woMntu: Kwizinto zokuthambisa kunye nemveliso yokunyamekela, i-hydroxypropylcellulose isetyenziswe njenge-thickener, i-stabilizer kunye ne-agent-forming agent kwiimveliso ezifana ne-creams, i-lotions kunye neentlobo zokunakekelwa kweenwele.

Izicelo zoShishino: Ngenxa yokwenziwa kwefilimu kunye neempawu zokubambelela, i-hydroxypropylcellulose ingasetyenziselwa kwiintlobo ezahlukeneyo zezicelo zoshishino, kubandakanywa iingubo, ukunamathela kunye ne-binder ekuveliseni amanqaku abunjiweyo.

Ishishini lokutya: Kushishino lokutya, i-hydroxypropylcellulose ingasetyenziswa njenge-thickener kunye ne-stabilizer kwimixube ethile yokutya.

Umzi-mveliso we-textile: I-Hydroxypropyl cellulose ingasetyenziswa kwishishini lempahla ye-textile kunye ne-film-forming kunye ne-adhesive properties ukunceda ekugqityweni kwempahla.

I-Hydroxypropyl cellulose yi-derivative cellulose derivative esetyenziswa ngokubanzi kumachiza, iimveliso zokunakekelwa komntu, kunye nezicelo ezahlukeneyo zoshishino ngenxa yokunyibilika kwayo, iipropati zokuguqula i-viscosity, amandla okwenza ifilimu, kunye nokuhambelana nezinye izinto zokusebenza. Ukuguquguquka kwayo kunye nokulawulwa kwe-synthesis kwenza i-polymer exabisekileyo kwiintlobo ezahlukeneyo zezicelo.