Yintoni isicelo se-CMC ekuqulunqweni kwamayeza?

ICarboxymethylcellulose (CMC) sisixhobo esisetyenziswa ngokubanzi ekuqulunqweni kwamayeza. I-polysaccharide e-soluble yamanzi ephuma kwi-cellulose, eyenziwe ngeeyunithi ze-glucose ezidityaniswe kunye neebhondi ze-glycosidic. I-CMC yi-non-ionic, ayinancasa, ayinavumba, kunye nomgubo omhlophe onganyibilikiyo kwizinyibilikisi ezininzi zezinto eziphilayo. Isetyenziselwa ukwakhiwa kwamachiza ukuphucula uzinzo, i-bioavailability, kunye nokhuseleko lwamachiza.

I-CMC isetyenziswa kwiintlobo ngeentlobo zokwenziwa kwamachiza, kubandakanywa iipilisi, iipilisi, ukunqunyanyiswa, i-emulsions, kunye nezithambiso. Isetyenziswa njenge-binder, i-disintegrant, i-arhente yokumisa, i-emulsifying agent, i-lubricant, kunye ne-stabilizer. Ikwasetyenziselwa ukunyusa i-viscosity ye-formulation kunye nokuphucula iimpawu zokuhamba kwee powders.

I-CMC isetyenziselwa iipilisi kunye nee-capsules ukuphucula iimpawu zokuhamba kwe powder, ukwandisa ukunyanzeliswa kwepowder, kunye nokuphucula ukuchithwa kunye nokutshatyalaliswa kwethebhulethi okanye i-capsule. Ikwasetyenziswa njengesibophelelo sokubamba ithebhulethi okanye i-capsule kunye. I-CMC isetyenziselwa ukunqunyanyiswa ukuphucula ukuzinza kokumiswa kunye nokwandisa i-viscosity yokunqunyanyiswa. Ikwasetyenziswa njenge-emulsifying agent yokuphucula ukuzinza kwe-emulsions.

I-CMC isetyenziswa kwi-ointments ukuphucula ukuzinza kwe-ointment kunye nokwandisa i-viscosity ye-ointment. Ikwasetyenziswa njenge-lubricant ukunciphisa ukukhuhlana phakathi kwe-ointment kunye nolusu.

I-CMC ikhuselekile ngokubanzi kwaye ayinayo ityhefu. Ivunywa ngokubanzi njengekhuselekile (GRAS) yi-US Food and Drug Administration (FDA). Ikwavunywa yi-Arhente ye-European Medicines Agency (EMA) ukuba isetyenziswe ekuqulunqeni amayeza.

I-CMC iyinxalenye ebalulekileyo yokwenziwa kwamayeza. Isetyenziselwa ukuphucula uzinzo, i-bioavailability, kunye nokhuseleko lwamachiza. Ngokuqhelekileyo ikhuselekile kwaye ayinayo ityhefu kwaye ivunywe yi-FDA kunye ne-EMA ukuze isetyenziswe ekuqulunqweni kwamayeza.