Iphezulu i-viscosity yeihydroxypropyl methylcellulose, ngcono ukusebenza kokugcinwa kwamanzi. I-Viscosity yiparameter ebalulekileyo yokusebenza kwe-HPMC. Okwangoku, abavelisi abahlukeneyo be-HPMC basebenzisa iindlela ezahlukeneyo kunye nezixhobo zokulinganisa i-viscosity ye-HPMC. Iindlela eziphambili zeHaake Rotovisko, Hoppler, Ubbelohde kunye neBrookfield.
Kwimveliso efanayo, iziphumo ze-viscosity ezilinganiswe ngeendlela ezahlukeneyo zahluke kakhulu, kwaye ezinye ziphinda ziphindwe kabini. Ke, xa uthelekisa i-viscosity, qiniseka ukuba uyenza phakathi kweendlela ezifanayo zokuvavanya, kubandakanya ubushushu, i-rotor, njl.
Ubungakanani besuntswana, incinci incinci, ngcono ukugcinwa kwamanzi. Emva kokuba iinqununu ezinkulu ze-cellulose ether zidibene namanzi, umphezulu uchitha ngokukhawuleza ukwenza i-gel, egubungela izinto eziphathekayo ukukhusela ukungena ngokuqhubekayo kwama-molecule amanzi. . Ichaphazela kakhulu isiphumo sokugcinwa kwamanzi kwi-ether ye-cellulose, kwaye ukunyibilika yenye yezinto zokukhetha i-cellulose ether. Ukulunga kukwayisalathisi sokusebenza esibalulekileyo se-methyl cellulose ether. I-MC esetyenziselwa udaka lwepowder eyomileyo iyadingeka ukuba ibe ngumgubo, kunye nomxholo wamanzi aphantsi, kwaye ukucolwa kwakhona kufuna i-20% ukuya kwi-60% ye-particle size ibe ngaphantsi kwe-63um. Ukulunga kuchaphazela ukunyibilika kwe-hydroxypropyl methylcellulose ether. I-coarse MC idla ngokuba yigranular, kwaye kulula ukuyinyibilika emanzini ngaphandle kwe-agglomeration, kodwa izinga lokuchithwa licotha kakhulu, ngoko ke akufanelekanga ukusetyenziswa kwidaka elomileyo. Kwidaka elomileyo lomgubo, i-MC isasazwa phakathi kwezinto zesamente ezifana nee-aggregates, iifilisi ezintle kunye nesamente. Umgubo ocolekileyo kuphela owaneleyo unokunqanda i-agglomeration ye-methyl cellulose ether xa ixutywa namanzi. Xa i-MC yongezwa ngamanzi ukunyibilikisa i-agglomerates, kunzima ukusabalalisa kunye nokuchithwa. I-MC ene-coarser fineness ayikona nje ukumosha, kodwa iyanciphisa amandla wendawo yodaka. Xa udaka olunjalo olulomileyo lwakhiwe kwindawo enkulu, isantya sokunyanga sodaka lwendawo eyomileyo siyancipha kakhulu, kwaye ukuqhekeka kwenzeka ngenxa yamaxesha ahlukeneyo okuphilisa. Ngodaka lokutshiza usebenzisa ukwakhiwa komatshini, ngenxa yexesha elifutshane lokuvuselela, ukulungelelaniswa kuyafuneka ukuba kube phezulu.
Ngokuqhelekileyo, okukhona i-viscosity iphezulu, ngcono isiphumo sokugcina amanzi. Nangona kunjalo, i-viscosity ephezulu kwaye iphakamileyo ye-molecular weight ye-MC, ukunciphisa okuhambelanayo kwi-solubility yayo, enefuthe elibi kumandla kunye nezakhiwo zokwakha zodaka. Ukuphakama kwe-viscosity, kuyabonakala ngakumbi umphumo wokuqina wodaka, kodwa awulingani. Ukuphakama kwe-viscosity, udaka olumanzi luya kuba lunamathele ngakumbi. Ngexesha lokwakha, iya kubambelela kwi-scraper kwaye ibe nokunamathela okuphezulu kwi-substrate. Kodwa yenza okuncinci ukunyusa amandla esakhiwo sodaka olumanzi ngokwalo. Ngexesha lokwakha, ukusebenza kwe-anti-sagging performance ayibonakali. Ngokuchasene noko, ezinye i-viscosity ephantsi kodwa ehlaziyiweyo ye-methyl cellulose ethers inomsebenzi obalaseleyo ekuphuculeni amandla okwakhiwa kodaka olumanzi.
Ubukhulu bexabiso le-ether ye-cellulose eyongeziweyo kwidaka, ngcono ukugcinwa kwamanzi, ukuphakama kwe-viscosity, ngcono ukugcinwa kwamanzi.
Ukucoleka kwe-HPMC nako kunefuthe elithile kugcino lwamanzi. Ngokubanzi, kwi-methyl cellulose ethers ezineviscosity efanayo kodwa ukucoleka okwahlukileyo, kwimeko yongezelelo olufanayo, okukhona ukucoleka, kokukhona isiphumo sokugcina amanzi singcono.
Ukugcinwa kwamanzi kwe-HPMC kukwanxulumene nobushushu obusetyenzisiweyo, kwaye ukugcinwa kwamanzi kwe-methyl cellulose ether kuncipha ngokunyuka kwamaqondo obushushu. Nangona kunjalo, kwizicelo ezibonakalayo, udaka olomileyo lomgubo luhlala lusetyenziswa kwiindawo ezishushu ezishushu kumaqondo obushushu aphezulu (angaphezulu kwama-40 degrees) kwiindawo ezininzi, ezinje ngodonga lwangaphandle lokutyabeka phantsi kwelanga ehlotyeni, oluhlala lukhawulezisa Ukunyangwa kwesamente kunye nokuqina kwesamente. udaka olomileyo. Ukuhla kokugcinwa kwamanzi kuye kwakhokelela ekuboneni okucacileyo ukuba zombini ukusebenza kunye nokumelana nokuqhekeka kuchaphazelekayo, kwaye kubaluleke kakhulu ukunciphisa umphumo wezinto zokushisa phantsi kweemeko ezinjalo. Nangona isongezelelo se-methyl hydroxyethyl cellulose ether okwangoku sithathwa njengephambili kuphuhliso lobuchwepheshe, ukuxhomekeka kwayo kubushushu kusengakhokelela ekubeni buthathaka kokusebenza kodaka olomileyo. Nangona isixa se-methyl hydroxyethyl cellulose (ifomula yasehlotyeni) yandisiwe, ukusebenza kunye nokumelana nokuqhekeka akukwazi ukuhlangabezana neemfuno zokusetyenziswa. Ngonyango oluthile olukhethekileyo, olufana nokunyusa izinga le-etherification, i-MC inokugcina umphumo wayo wokugcinwa kwamanzi ngcono kumaqondo obushushu aphezulu, ukuze ikwazi ukubonelela ukusebenza okungcono phantsi kweemeko ezinzima.
Ixesha lokuposa: Oct-20-2022