Ukukhutshwa okuzinzileyo kunye namalungiselelo okukhutshwa okulawulwayo: I-cellulose ethers efana ne-HPMC (i-hydroxypropyl methylcellulose) isetyenziswa rhoqo njengezinto ze-hydrogel skeleton kumalungiselelo okukhululwa okuqhubekayo. Inokulawula izinga lokukhululwa kweziyobisi emzimbeni womntu ukufezekisa iziphumo zonyango. Ibanga eliphantsi le-viscosity ye-HPMC ingasetyenziswa njenge-adhesive, thickener kunye ne-agent exhomayo, ngelixa i-high-viscosity grade HPMC isetyenziselwa ukulungiselela iipilisi ezidibeneyo ze-skeleton, i-capsules ekhutshwe ngokuqhubekayo, kunye ne-hydrophilic gel skeleton skeletons-release tablets.
I-ejenti yokwenza ifilimu yokwambathisa: I-HPMC ineempawu ezilungileyo zokwenza ifilimu, kwaye ifilimu eyenziwe iyunifomu, icacile, inzima, kwaye akukho lula ukuyithobela. Inokuphucula uzinzo lwechiza kwaye ithintele ukujika kombala. Uxinzelelo oluqhelekileyo lwe-HPMC yi-2% ukuya kwi-10%.
I-excipients zamachiza: I-cellulose ethers idlala indima ebalulekileyo ekubunjweni kokulungiswa njengezinto ezincedisa amayeza, ezifana ne-pellets-release-release-release, i-skeleton-release preparations, i-coated-release-release preparations, i-capsules ekhutshwe ngokuqhubekayo, iifilimu ezizinzileyo zeziyobisi, i-resin-resin ukukhululwa kwamalungiselelo kunye namalungiselelo olwelo oluzinzileyo.
I-Microcrystalline Cellulose (MCC): I-MCC luhlobo lwe-cellulose olusetyenziswa ngokubanzi kwishishini lamachiza, ngokukodwa kwiinkqubo zokunyanzeliswa ngokuthe ngqo kunye ne-granulation ezomileyo ezifana ne-roller compaction ukulungiselela iipilisi ezixinzelelweyo okanye iigranules.
I-Bioadhesives: I-cellulose ethers, ngokukodwa i-nonionic kunye ne-anionic ether derivatives efana ne-EC (ethylcellulose), i-HEC (i-hydroxyethylcellulose), i-HPC (i-hydroxypropylcellulose), i-MC (i-methylcellulose), i-CMC (i-carboxymethylcellulose) okanye i-HPMC (i-hydroxypropylmethylsivecellulose esetyenziswa kwi-bio). Ezi polymers zingasetyenziselwa ngomlomo, i-ocular, i-vaginal kunye ne-transdermal bioadhesives, yodwa okanye idibene nezinye iipolymers.
I-Thickeners kunye ne-Stabilizers: I-cellulose derivatives isetyenziswa ngokubanzi ukutyebisa izisombululo zamachiza kunye neenkqubo zokusasazeka ezifana ne-emulsions kunye nokumiswa. Ezi polymers zinokunyusa i-viscosity yezisombululo zeziyobisi ezingenamanzi ezifana nezisombululo zokugquma ezisekelwe kwi-organic. Ukwandisa i-viscosity yezisombululo zamachiza kunokuphucula i-bioavailability ye-topical and mucosal preparations.
Izigcwalisi: I-Cellulose kunye ne-derivatives yayo isetyenziswa ngokuqhelekileyo njengabazalisi kwiifom zedosi eqinile ezifana neepilisi kunye neepilisi. Ziyahambelana nezinye izinto ezincedisayo, i-pharmacologically inert, kwaye ayigaywanga yi-enzymes yesisu somntu.
Izibophelelo: I-cellulose ethers isetyenziswa njengezibophelelo ngexesha lenkqubo yegranulation ukunceda iigranules zenze kwaye zigcine ingqibelelo yazo.
Iipilisi zezityalo: Ii-ether ze-cellulose zikwasetyenziselwa ukwenza ii-capsules zezityalo, enye indlela ehambelana nokusingqongileyo kwii-capsules zezilwanyana eziphuma kwizilwanyana.
Iinkqubo zokuhanjiswa kweziyobisi: Ii-ether ze-cellulose zingasetyenziselwa ukuphuhlisa iinkqubo ezahlukeneyo zokuhanjiswa kweziyobisi, kubandakanywa ukukhutshwa okulawulwayo kunye neenkqubo zokulibaziseka, kunye neenkqubo zokukhutshwa kweziyobisi kwisayithi okanye ngexesha elithile.
Ukusetyenziswa kwe-cellulose ethers kwishishini lamayeza liyaqhubeka nokukhula, kwaye ngophuhliso lweefom zedosi entsha kunye nezinto ezintsha ezincedisayo, ubungakanani bemfuno yayo yentengiso kulindeleke ukuba yande ngakumbi.
Ixesha lokuposa: Oct-31-2024