Ngawaphi amabakala ahlukeneyo e-HPMC?

I-HPMC, okanye i-hydroxypropyl methylcellulose, luhlobo lwe-cellulose derivative edla ngokusetyenziswa njenge-agent ejiyayo, i-emulsifier, kunye ne-stabilizer kwiimveliso ezahlukeneyo. Ngumgubo omhlophe, ongenavumba, ongenancasa onyibilika emanzini abandayo kwaye awunyibiliki emanzini ashushu.

I-HPMC ifumaneka kumabanga ahlukeneyo, ngalinye lineempawu zalo ezizodwa kunye nokusetyenziswa. Amabanga e-HPMC asekelwe kwiqondo lokutshintshwa (DS) kwamaqela e-hydroxypropyl, engumlinganiselo wenani lamaqela e-hydroxypropyl ngeyunithi ye-anhydroglucose. Okukhona iphezulu i-DS, kokukhona amaqela e-hydroxypropyl ekhona kwaye kokukhona i-hydrophilic i-HPMC.

Amabanga e-HPMC ahlulwe abe ngamacandelo amathathu aphambili: i-DS ephantsi, i-DS ephakathi, kunye ne-DS ephezulu.

I-DS HPMC ephantsi idla ngokusetyenziswa kwizicelo apho i-viscosity ephantsi kunye namandla ejeli aphantsi afunwayo. Eli bakala lidla ngokusetyenziswa ekutyeni nakwiziselo, njenge-ayisikrimu, iisosi, kunye neegravies. Ikwasetyenziswa kwizicelo zamachiza, ezifana neetafile kunye neecapsules.

I-Medium DS HPMC isetyenziswa kwizicelo apho i-viscosity ephezulu kunye namandla ejeli afunwayo. Eli bakala lihlala lisetyenziswa kwizicelo zokutya kunye neziselo, ezifana neejam kunye nejeli, kunye nezicelo zamachiza, ezifana ne-ointments kunye ne-creams.

High DS HPMC isetyenziswa kwizicelo apho viscosity eliphezulu kakhulu kunye namandla gel zifunwa. Eli bakala lihlala lisetyenziswa kwizicelo zokutya kunye neziselo, ezifana netshizi kunye neyogathi, kunye nakwizicelo zamayeza, ezinje ngee-suppositories kunye neepessaries.

Ukongeza kwiindidi ezintathu eziphambili ze-HPMC, kukwakho amacandelwana amaninzi. Ezi subcategories zisekelwe kwiqondo lokutshintshwa, ubungakanani be-particle size, kunye nohlobo lweqela le-hydroxypropyl.

Iqondo lokutshintshwa kwamacandelwana asekelwe kwiqondo lokutshintshwa kwamaqela e-hydroxypropyl. Ezi zintlu ziphantsi kwe-DS (0.5-1.5), i-DS ephakathi (1.5-2.5), kunye ne-DS ephezulu (2.5-3.5).

Iicandelwana zobungakanani besuntswana zisekelwe kubungakanani bamaqhekeza. Ezi subcategories zilungile (ngaphantsi kwe-10 microns), eziphakathi (10-20 microns), kunye ne-coarse (ngaphezu kwe-20 microns).

Uhlobo lwee-subcategories zeqela le-hydroxypropyl zisekelwe kuhlobo lweqela le-hydroxypropyl elikhoyo kwi-HPMC. Ezi zintlu zingaphantsi yi-hydroxypropyl methylcellulose (HPMC), i-hydroxypropyl ethylcellulose (HPEC), kunye ne-hydroxypropyl cellulose (HPC).

I-HPMC sisithako esisebenzayo kwaye sisetyenziswa ngokubanzi kwiimveliso ezahlukeneyo. Amabanga ahlukeneyo e-HPMC asekelwe kwiqondo lokutshintshwa, ubungakanani besuntswana, kunye nohlobo lweqela le-hydroxypropyl, kwaye ibakala ngalinye lineempawu zalo ezizodwa kunye nokusetyenziswa.