IHydroxypropylcellulose (HPC) yinto ebalulekileyo ephuma kwiselulosi esetyenziswa ngokubanzi kumayeza, ukutya kunye neendawo zokuthambisa. Ukusetyenziswa kwayo ekunqunyanyisweni kugqame ngakumbi, ngakumbi ngokutyeba kwayo, ukuzinzisa kunye neempawu zokunyibilikisa ukuqinisa uzinzo lokunqunyanyiswa.
Iimpawu eziphambili ze-hydroxypropylcellulose
I-Hydroxypropyl cellulose yi-ether ye-cellulose e-nonionic efunyenwe nge-hydroxypropylation ye-cellulose yendalo. Iqela le-hydrophilic hydroxypropyl lingeniswa kwisakhiwo salo sekhemikhali, linika ukunyibilika okuhle kunye neempawu ezityebileyo emanzini. I-HPC inezi mpawu zilandelayo:
Ukunyibilika okuhle: I-HPC inokunyibilika kumanzi abandayo kunye nashushu, yenze isisombululo esicacileyo kunye ne-viscous.
I-biocompatibility ephezulu: I-HPC ine-biocompatibility efanelekileyo kunye ne-toxicity ephantsi, ngoko isetyenziswa ngokubanzi kumashishini amayeza kunye nokutya.
Uzinzo olomeleleyo lwe-thermal: I-HPC inozinzo oluphezulu lwe-thermal kwaye inokugcina iimpawu zayo zokuqina kunye nokuzinzisa ngaphakathi kwinqanaba elithile lobushushu.
isiphumo sokuqina
Omnye weyona misebenzi iphambili ye-HPC ekumisweni kukutyeba. Ngokongeza inani elifanelekileyo le-HPC ekumisweni, i-viscosity ye-liquid inganyuswa kakhulu, ngaloo ndlela inciphisa isantya sokumisa iincinci eziqinileyo. Ngokomthetho we-Stokes, isantya sokumisa amasuntswana sihambelana ngokungafaniyo ne-viscosity yolwelo. Ngoko ke, ngokunyusa i-viscosity yokumiswa, ukulungiswa kweengqungquthela kunokulibaziseka ngokufanelekileyo kunye nokuzinza kokumiswa kuphuculwe.
Isiphumo sokuqina kwe-HPC sivela ikakhulu kubunzima bayo obuphezulu bemolekyuli kunye nesiphumo sokungena phakathi kwamakhonkco emolekyuli. Xa i-HPC ichithekile emanzini, iimolekyuli ze-long-chain zityhila kwaye zidibanise omnye nomnye kwisisombululo, zenze isakhiwo sothungelwano esiyinkimbinkimbi. Esi sakhiwo sothungelwano sinokunyusa kakhulu i-viscosity yesisombululo, okwenza kube nzima ukuba amasuntswana aqinileyo ahambe kulwelo, ngaloo ndlela aphucule ukuzinza kokumiswa.
Isiphumo sokuzinzisa
Enye indima ebalulekileyo ye-HPC kukuphucula ukuzinza kokunqunyanyiswa. Ukongeza kwisiphumo sayo sokuqina, i-HPC ikwanomsebenzi ogqwesileyo wobuso kunye nokukwazi ukwenza umaleko wokuncamathelisa okhuselayo. Iimolekyuli ze-HPC zinokubhengezwa kumphezulu wamasuntswana aqinileyo ukwenza umaleko okhuselayo weglue ukuthintela amasuntswana ekudibaneni nasekuzinziseni.
Lo maleko wokuncamathelisa okhuselayo uzinzisa ukunqunyanyiswa nge-electrostatic repulsion kunye neziphumo ezithintelweyo zesteric. Okokuqala, iqela le-hydroxypropyl kwi-molecule ye-HPC inokwenza iibhondi ze-hydrogen kunye neemolekyuli zamanzi, ukwandisa i-hydrophilicity ye-particle surface kunye nokuphucula ukusasazeka kweengqungquthela emanzini. Okwesibini, ubukho bamaketanga eemolekyuli ze-HPC buya kwenza umqobo womzimba kwi-particle surface, ukukhusela ukudibanisa ngokuthe ngqo phakathi kweengqungquthela, ngaloo ndlela kuncitshiswe i-particle aggregation kunye ne-sedimentation.
I-Solubilization
Isiphumo solubilizing ye-HPC ekumisweni ayinakuhoywa. Kwamanye amachiza anganyibiliki kakuhle okanye izithako ezisebenzayo, i-HPC inokunyusa ukunyibilika kwayo emanzini ngokwenza ii-molecular inclusion complexes okanye iimicelles. Iqela le-hydroxypropyl kwi-molecule ye-HPC linokwenza intsebenziswano ebuthathaka (efana neebhondi ze-hydrogen okanye i-van der Waals forces) kunye neemolekyuli zezinto ezinyibilikayo, ngaloo ndlela ziphucula ukunyibilika kwayo emanzini.
Ngokusebenzisa le mpembelelo ye-solubilization, i-HPC ayinako ukunyusa kuphela ukunyibilika kwezinto ezinganyibiliki kakuhle ekumisweni, kodwa ziphinde ziphucule ukuhanjiswa kwazo okufanayo kulwelo, kuphuculwe ngakumbi ukuzinza kokumiswa.
Usetyenziso
Kwishishini lamachiza, i-HPC isetyenziswa ngokuqhelekileyo kwiindidi zamalungiselelo amayeza afana nokumiswa komlomo, iinaliti, kunye namalungiselelo e-ophthalmic. Ngokomzekelo, ekumisweni komlomo, i-HPC inokuphucula ukumiswa kunye nokuzinza kweyeza, ukuqinisekisa ukuba iyeza alihlali ngexesha lokugcinwa, ngaloo ndlela iphucula ukusebenza kunye nokukhuseleka kweyeza. Kwiinaliti, i-HPC inokunyusa i-bioavailability yamachiza kwaye iphucule ukusebenza kwayo ngokudibanisa.
Kwishishini lokutya, i-HPC isetyenziswa ngokuqhelekileyo kwiimveliso zokunqunyanyiswa ezifana nejusi, iimveliso zobisi kunye ne-condiments. I-HPC inokuphucula i-viscosity kunye nokuzinza kokumiswa, ukuthintela ukuhlaliswa kunye nokuhlelwa kweengqungquthela eziqinileyo, kunye nokuqinisekisa ukufana kunye nokunambitha kwemveliso.
IHydroxypropylcellulose idlala indima ebalulekileyo ekwandiseni uzinzo lokunqunyanyiswa. Ngokuqina kwayo, ukuzinzisa kunye neempawu zokunyibilikisa, i-HPC inokunyusa kakhulu i-viscosity yokumiswa, ukunciphisa isantya sokumisa amasuntswana aqinileyo, yenza umaleko okhuselayo weglue ukuthintela ukudityaniswa kwamasuntswana, kunye nokwandisa ukunyibilika kwezinto ezinganyibiliki kakuhle. Ezi zakhiwo zenza i-HPC isetyenziswe ngokubanzi kwiinkalo zamachiza, ukutya kunye nezithambiso, ibe yinto ephambili yokuphucula ukuzinza kokumiswa.
Ixesha lokuposa: Jul-21-2024