Ngaba i-hypromellose iyingozi emzimbeni?

IHypromellose, ekwabizwa ngokuba yi-hydroxypropyl methylcellulose, yi-semi-synthetic, inert, kunye ne-polymer enyibilikayo emanzini esetyenziswa ngokubanzi kumashishini ahlukeneyo. Isetyenziswa ngokuqhelekileyo njengesongezo sokutya, i-thickener, i-emulsifier, kunye ne-excipient yamayeza ekuveliseni iipilisi, ii-capsules, kunye namalungiselelo ophthalmic. Kweli nqaku, siza kuphonononga ukhuseleko lwe-hypromellose kunye nemiphumo yayo yezempilo.

Ukhuseleko lweHypromelose

I-Hypromellose ngokuqhelekileyo ithathwa njengekhuselekile ukuba isetyenziswe ngabasemagunyeni abahlukahlukeneyo abalawulayo, kuquka i-United States Food and Drug Administration (FDA), i-European Food Safety Authority (EFSA), kunye ne-Joint FAO / WHO yeNgcali yeKomiti yezongezo zokutya (JECFA). Ihlelwa njenge-GRAS (eyaziwa ngokubanzi njengekhuselekile) isongezo sokutya yi-FDA, oku kuthetha ukuba inembali ende yokusetyenziswa ngokukhuselekileyo ekutyeni kwaye akunakwenzeka ukuba ibangele ingozi xa isetyenziswe kwiimali eziqhelekileyo.

Kumachiza, i-hypromellose isetyenziswa ngokubanzi njenge-excipient ekhuselekileyo kunye nokunyamezela kakuhle. Idweliswe kwi-US Pharmacopeia kwaye isetyenziswa ngokubanzi ekwenzeni zombini iifom zedosi eqinileyo kunye neyolwelo. Ikwasetyenziswa njenge lubricant yamehlo kwaye ithathwa njengekhuselekile ukuba ingasetyenziswa kwiilensi zoqhagamshelwano, iinyembezi zokwenziwa, kunye nezinye iimveliso zamehlo.

Uphononongo lubonise ukuba i-hypromellose inetyhefu yomlomo ephantsi kwaye ayifuntshwa ngumzimba. Idlula kwi-gastrointestinal tract ngaphandle kokuphulwa, kwaye ikhutshwe kwi-lindle. I-Hypromellose ikwabonwa njengekhuselekile ukuba isetyenziswe kubasetyhini abakhulelweyo nabancancisayo, kunye nabantwana, ngaphandle kweziphumo ezibi ezaziwayo.

Iziphumo zeMpilo ezinokubakho zeHypromellose

Ngelixa i-hypromellose ngokuqhelekileyo ithathwa njengekhuselekile ukuba isetyenziswe, kukho ezinye iziphumo zempilo ezinokuthi ziqwalaselwe.

Iziphumo zeGastrointestinal

IHypromellose yipolima enyibilikayo emanzini efunxa amanzi kwaye yenze into efana nejeli xa idibana nolwelo. Oku kunokubangela ukwanda kwe-viscosity kwi-gastrointestinal tract, enokuthi icuthe ixesha lokuhamba lokutya ngokusebenzisa inkqubo yokugaya. Oku kunokubangela ukuqunjelwa, ukuqunjelwa, kunye nokungonwabi kwesisu kwabanye abantu, ngakumbi ukuba kusetyenziswe kakhulu.

Iintshukumo zokwalana

Ukuchasana nokwaliwa kwi-hypromellose kunqabile, kodwa kunokwenzeka. Iimpawu zokungaphenduli komzimba zinokubandakanya ukurhawuzelelwa, ukurhawuzelelwa, ukudumba kobuso, imilebe, ulwimi, okanye umqala, ukuphefumla nzima, kunye ne-anaphylaxis (i-allergies enzima, enokusongela ubomi). Ukuba ufumana nayiphi na yezi mpawu emva kokutya i-hypromellose, funa unyango ngokukhawuleza.

Ukucaphuka kwamehlo

I-Hypromellose isetyenziswa ngokuqhelekileyo njenge-lubricant ye-ophthalmic ekuveliseni amaconsi amehlo kunye namanye amalungiselelo e-ophthalmic. Nangona ngokuqhelekileyo ithathwa njengekhuselekile ukuba isetyenziswe emehlweni, abanye abantu banokufumana ukucaphuka kwamehlo okanye ezinye iziphumo ezibi. Iimpawu zokucaphuka kwamehlo zinokubandakanya ububomvu, ukurhawuzelelwa, ukutshisa, nokukrazuka.

Ukusebenzisana kweziyobisi

I-Hypromellose inokunxibelelana namayeza athile, ngakumbi lawo afuna indawo ephantsi ye-pH yokufunxa. Oku kungenxa yokuba i-hypromellose yenza into efana nejeli xa idibana nolwelo, olunokuthi lucothise ukunyibilika kunye nokufunxa amayeza. Ukuba uthatha nawaphi na amayeza, kubandakanywa neyeza okanye amayeza angaphezulu kwe-counter, kubalulekile ukubonisana nomboneleli wakho wezempilo ngaphambi kokuba uthathe i-hypromellose okanye naziphi na izongezo zokutya.

Ukuqukumbela

I-hypromellose ithathwa njengekhuselekile ukuba isetyenziswe ngabasemagunyeni abahlukeneyo abalawulayo. Isetyenziswa ngokubanzi njengesongezo sokutya, i-thickener, kunye ne-emulsifier, kunye ne-excipient yamayeza ekuveliseni iipilisi, ii-capsules, kunye namalungiselelo ophthalmic.