HPMC Hypromellose

Hydroxypropyl Methylcellulose(HPMC), yikhompawundi yeekhemikhali eziguquguqukayo kunye nefomula [C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n]x, apho m imele iqondo lokutshintshwa kwemethoxy kwaye n imele idigri yehydroxypropoxy. endaweni. Ithathwe kwi-cellulose, i-polymer yendalo efunyenwe kwiindonga zeeseli zezityalo. I-HPMC ayinavumba, ayinancasa, kwaye ayinatyhefu. Ineempawu ezahlukeneyo ze-physicochemical ezifana nokunyibilika emanzini, iipropathi ze-gelation ze-thermal, kunye nokukwazi ukwenza iifilimu, okwenza ukuba isetyenziswe ngokubanzi kumashishini amaninzi.

Kwishishini lamachiza, i-HPMC isetyenziswa kakhulu njenge-excipient-into eyenziwe ecaleni kwesixhobo esisebenzayo seyeza, ngenjongo yokuzinzisa ixesha elide, ukudibanisa iifomyulo eziqinileyo eziqulethe izithako ezinamandla ezisebenzayo kwiimali ezincinci (oku kudla ngokubhekiselwa kuzo. njengesihluzi, isinyibilikisi, okanye umthwali), okanye ukomeleza ukufunxa okanye ukunyibilika. I-HPMC capsules yenye i-gelatin capsules yemifuno kwaye isetyenziswa kwimixube elawulwayo yokukhululwa, evumela ukukhutshwa okucothayo kwechiza ngokuhamba kwexesha. Izisombululo ze-HPMC zinokusebenza njenge-viscolyzers ukunyusa i-viscosity yezisombululo ze-ophthalmic, ukuphucula ukubambelela kwizinto eziphilayo, kunye nokwandisa ixesha lokuhlala kweziyobisi kumphezulu we-ocular.

Kushishino lokutya, i-HPMC yamkelwa njengesongezo sokutya esikhuselekileyo (E464) kwaye isebenza ngemisebenzi emininzi efana ne-emulsifier, i-agent etyebisayo, kunye ne-stabilizer. Isetyenziselwa ukuveliswa kokutya okwahlukeneyo ukuphucula ukuthungwa, ukugcina ukufuma, kunye nokwenza iifilimu ezidliwayo. Ipropathi ye-thermal gelation ye-HPMC ixabiseke ngokukodwa kwizicelo ezifuna i-gelling kumaqondo athile obushushu, njengakwiiresiphi zemifuno kunye ne-vegan apho inokuthatha indawo ye-gelatin. I-HPMC ikwanegalelo kubomi beshelufa kunye nomgangatho weempahla ezibhakiweyo, iisosi, kunye nezimuncumuncu ngokulawula icrystallization kunye nokufuma.

Ishishini lokwakha lixhamla kwi-HPMC ekwenzeni izinto zokwakha. Ukusetyenziswa kwayo kubandakanya ukusebenza njenge-binder kunye ne-arhente yokugcina amanzi kwi-mortars, i-plasters, kunye ne-coatings, ukuphucula ukusebenza, ukunciphisa ukusetyenziswa kwamanzi, kunye nokwandisa ixesha elivulekileyo - ixesha apho imathiriyeli ihlala isebenziseka. I-HPMC iphucula iipropathi zemixube esekwe kwisamente, ibonelela ngokuncamathela okungcono, ukusasazeka, kunye nokuchasana nokuncipha.

Kwizimonyo kunye neshishini lokhathalelo lomntu, i-HPMC isebenza njenge-ejenti yokwenza ifilimu, i-emulsifier, kunye ne-rheology modifier kwiimveliso ezifana ne-lotions, i-creams, kunye ne-gel zeenwele. Ukuhambelana kwayo kunye neentlobo ezahlukeneyo zesikhumba kunye nokukwazi ukuzinzisa i-emulsions yokuphucula ukusebenza kwemveliso kunye nokuphila ixesha elide. iipropati HPMC kaThixo hydration zenza ukuba isithako ezinqwenelekayo iimveliso inskin ukhathalelo, inceda ukugcina ukufuma kunye nokubonelela imvakalelo agudileyo. Isishwankathelo, ukuguquguquka kwe-HPMC kubandakanya amayeza, ukutya, ulwakhiwo, kunye nezinto zokuthambisa, iqaqambisa ukubaluleka kwayo njengesithako esisebenza ngeendlela ezininzi kwizicelo ezahlukeneyo.