IHydroxypropylmethylcellulose (HPMC) yipolymer ephuma kwi-cellulose esetyenziswa ngokuqhelekileyo kumashishini ahlukeneyo, kubandakanywa amayeza, ukutya kunye nokwakhiwa. Ubushushu bunokuba nempembelelo enkulu ekusebenzeni kunye nokuziphatha kwe-HPMC.
1. Ukunyibilika kunye nonyibiliko:
Ukunyibilika: I-HPMC ibonisa ukunyibilika okuxhomekeke kubushushu. Ngokuqhelekileyo, inyibilika ngakumbi emanzini abandayo kunasemanzini ashushu. Le propathi ibalulekile kwimixube yoxubo-mayeza efuna ukukhutshwa kwechiza okulawulwayo.
Ukutshatyalaliswa: Umlinganiselo wokuchithwa kweendlela ze-HPMC zichatshazelwa bubushushu. Amaqondo obushushu aphezulu ngokubanzi akhokelela ekuphelisweni ngokukhawuleza, ngaloo ndlela echaphazela i-kinetics yokukhululwa kwechiza kwizicelo zoxubo-mayeza.
2. I-Gelation kunye ne-viscosity:
I-Gelation: I-HPMC inokwenza i-gel kwisisombululo esinamanzi, kwaye inkqubo ye-gelation ichatshazelwa ngubushushu. I-Gelation idla ngokukhuthazwa kumaqondo okushisa aphezulu, okubangela ukubunjwa kwenethiwekhi ye-gel ezinzile.
I-Viscosity: Ubushushu budlala indima ephambili ekumiseleni i-viscosity yezisombululo ze-HPMC. Ngokuqhelekileyo, ukunyuka kweqondo lokushisa kubangela ukuhla kwe-viscosity. Le propati ibaluleke kakhulu ekuqulunqeni iingubo, i-adhesives kunye nezinye izicelo ezifuna ulawulo lwe-viscosity.
3. Ukwenziwa kwefilimu:
Ukugquma ifilimu: Kwishishini lamachiza, i-HPMC isetyenziswa ngokubanzi kwifilimu yokugquma iipilisi. Ubushushu buchaphazela iipropati zokwenza ifilimu yezisombululo ze-HPMC. Ukushisa okuphezulu kunokunyusa inkqubo yokwenza ifilimu kunye nokuchaphazela umgangatho kunye neempawu zefilimu yokugqoka.
4. Uzinzo lweThermal:
Ukuthotywa: I-HPMC ibonisa ukuzinza kwe-thermal ngaphakathi koluhlu oluthile lobushushu. Ngaphandle kolu luhlu, ukuthotywa kwe-thermal kunokwenzeka, kubangele ukulahlekelwa kwe-viscosity kunye nezinye izinto ezifunwayo. Ukuzinza kwe-Thermal ye-HPMC kufuneka kuthathelwe ingqalelo kwizicelo ezahlukeneyo.
5. Utshintsho lwenqanaba:
Ubushushu beGlass Transition (Tg): I-HPMC idlula kwinguqu yeglasi kwiqondo lobushushu elithile elibizwa ngokuba liqondo lobushushu beglasi (Tg). Ngaphezulu kwe-Tg, i-polymer transitions ukusuka kwiglasi ukuya kwi-rubbery state, echaphazela iimpawu zayo zomatshini.
6. Ukusebenzisana kweziyobisi-Polymer:
Ulwakhiwo oluntsonkothileyo: Kuqulunqo lwamayeza, ubushushu buchaphazela intsebenziswano phakathi kwe-HPMC kunye nechiza. Ukutshintsha kweqondo lobushushu kunokukhokelela ekwakhekeni kwee-complex, ezichaphazela ukunyibilika kweziyobisi kunye nokukhululwa.
7. Uzinzo lwefomula:
Uzinzo lwe-Freeze-Thaw: I-HPMC iqhele ukusetyenziswa kwimixube engumkhenkce, efana nezimuncumuncu ezikhenkcezisiweyo. Ukuzinza kwayo ngexesha lemijikelezo ye-freeze-thaw ichaphazeleka kukutshintsha kweqondo lokushisa. Ukuqonda imiphumo yobushushu kubalulekile ukugcina umgangatho wemveliso.
Ubushushu bunempembelelo enkulu kwi-solubility, i-dissolution, i-gelation, i-viscosity, ukubunjwa kwefilimu, ukuzinza kwe-thermal, utshintsho lwesigaba, ukusebenzisana kweziyobisi-polymer, kunye nokuzinza kwe-HPMC. Abaphandi kunye nabaqulunqi kufuneka baqwalasele ngononophelo ezi zakhiwo ezinxulumene nobushushu xa usebenzisa i-HPMC kwizicelo ezahlukeneyo.
Ixesha lokuposa: Jan-20-2024