I-Hydroxypropyl methylcellulose (HPMC) i-polymer ebalulekileyo yamanzi e-soluble esetyenziswa ngokubanzi kumashishini okwakha, amayeza, ukutya kunye nezithambiso, ngakumbi kwintsimi yokunamathela. Ulawulo lwe-viscosity lwe-HPMC lubalulekile ekusebenzeni kwemveliso. kubalulekile. Ukuphucula i-viscosity ye-HPMC kwi-adhesives inokufezekiswa ngokulungelelanisa iimpawu zayo zomzimba kunye neekhemikhali, kunye nokuphucula ukuqulunqwa kunye nokusingqongileyo kwesicelo.
1. Lungisa ubunzima bemolekyuli ye-HPMC
I-viscosity ye-HPMC ikakhulu ixhomekeke kubunzima bayo bemolekyuli. Ngokuqhelekileyo, ubukhulu be-molecular weight, buphezulu i-viscosity. Ngokukhetha i-HPMC enobunzima obufanelekileyo bemolekyuli, i-viscosity ye-adhesive inokulawulwa ngokufanelekileyo. Ngokubanzi, i-HPMC enobunzima obuphezulu bemolekyuli iya kwandisa i-viscosity ye-adhesive, kodwa iya kuchaphazela ukuhamba kunye nokusebenza. Ngoko ke, ibhalansi phakathi kwe-viscosity kunye nokusebenza kufuneka ifunyanwe kwizicelo eziphathekayo.
2. Lawula iqondo lokutshintshwa kwe-HPMC
I-HPMC yimveliso efunyenwe kwi-methylcellulose nge-partial hydroxypropylation reaction. Iqondo layo lokutshintshwa (oko kukuthi, iqondo lokutshintshwa kwe-hydroxypropyl kunye namaqela e-methyl) kunempembelelo ebalulekileyo kwi-viscosity. Izidanga eziphakamileyo zokutshintsha ngokubanzi zinciphisa i-viscosity ye-HPMC, ngelixa izidanga ezisezantsi zokutshintshana zonyusa i-viscosity. Ngoko ke, ngokulungelelanisa iqondo lokutshintshwa kwe-HPMC, ulawulo olusebenzayo lwe-viscosity lunokufezekiswa. Kwiimeko ezahlukeneyo zesicelo, i-HPMC enemigangatho eyahlukeneyo yokutshintshwa ingafuneka ukuhlangabezana neemfuno zokusebenza kwe-adhesive.
3. Ukulawulwa kobushushu bokutshatyalaliswa
I-solubility kunye ne-viscosity ye-HPMC inxulumene ngokusondeleyo nobushushu. Ngokubanzi, i-HPMC ine-viscosity ephezulu xa inyibilikiswa kumaqondo obushushu asezantsi. Ngokulungisa ukushisa kwe-HPMC ngexesha lokulungiselela ukunamathela, i-viscosity yemveliso yokugqibela inokulungiswa. Umzekelo, ukunyibilikisa i-HPMC kumaqondo obushushu aphezulu kunokubangela i-viscosity esezantsi, kodwa ukunyuka kancinci kwi-viscosity njengoko ubushushu buyancipha. Ngoko ke, ngokulawula ubushushu ngexesha lenkqubo yokwakha, ukulungiswa okuguquguqukayo kwe-viscosity kunokufezekiswa.
4. Yongeza i-thickener
Kwifomula yokuncamathelisa ye-HPMC, ukongeza inani elifanelekileyo le-thickener kunokunyusa ngokufanelekileyo i-viscosity. Izityebi eziqhelekileyo ziquka i-xanthan gum, i-carbomer, i-cellulose derivatives, njl. Ezi zityebi zisebenza ngokubambisana ne-HPMC ukunyusa i-viscosity iyonke ye-adhesive. Ukongeza, i-thickeners inokuphucula ukuzinza kunye nokumelana ne-sag ye-adhesive, inika ukusebenza kakuhle kwisicelo.
5. Lungisa ugxininiso lwesisombululo se-HPMC
Ukuxinwa kwesisombululo se-HPMC emanzini kunempembelelo ngqo kwi-viscosity. I-concentration ephezulu, inkulu i-viscosity. Kwizicelo eziphathekayo, i-viscosity ye-adhesive inokuguqulwa ngokuguquguqukayo ngokulawula ukuxinwa kwesisombululo se-HPMC. Ngokomzekelo, xa ulungiselela i-adhesive, i-viscosity inokunyuswa ngokunyusa ngokuthe ngcembe inani le-HPMC, okanye i-viscosity ingancitshiswa ngokuhlanjululwa.
6. Ukulungiswa kweresiphi
I-viscosity ye-adhesive ye-HPMC ayixhomekeke kuphela kwiimpawu ze-HPMC ngokwayo, kodwa inxulumene ngokusondeleyo nayo yonke inkqubo yokuqulunqa. Ngokulungisa iintlobo kunye nomlinganiselo wamanye amacandelo kwifomula, njengama-fillers, i-co-solvents, i-stabilizers, njl., i-viscosity inokulungiswa ngokufanelekileyo. Umzekelo, ukonyusa inani le-filler ngokufanelekileyo kunokonyusa i-viscosity, kodwa ukugcwaliswa okuninzi kunokubangela ukuba incamathiso ibe nolwelo oluphantsi kwaye kube nzima ukuyifaka. Ke ngoko, uyilo lwefomula olufanelekileyo ngundoqo ekuphuculeni i-viscosity ye-HPMC.
7. Ukulungelelaniswa kwexabiso le-pH
I-viscosity ye-HPMC iphinda ichaphazeleke yi-pH yesisombululo. Kuluhlu oluthile, i-viscosity ye-HPMC iyatshintsha ngexabiso le-pH. Ngokubanzi, i-HPMC ibonisa i-viscosity ephezulu ngokungathathi hlangothi kwiindawo ezibuthathaka ze-alkaline, ngelixa phantsi kweemeko ze-asidi eqinile okanye i-alkaline, i-viscosity inokuncipha kakhulu. Ngoko ke, ngokulungelelanisa i-pH ye-adhesive, ulawulo lwe-viscosity lunokufezekiswa. Umzekelo, kwizicelo ezithile, i-pH inokuzinziswa ngokongeza ii-buffers ukugcina i-viscosity ezinzileyo.
8. Sebenzisa ii-agent ezidibanisayo
Kwezinye iimeko, ukongezwa kwee-agent ezidibanisayo kunokunyusa kakhulu i-viscosity ye-HPMC. Ii-agent ezidibanisa umnqamlezo zingenza i-cross-links emzimbeni okanye iikhemikhali phakathi kwee-molecule ze-HPMC kunye nokuphucula intsebenziswano phakathi kwamatyathanga eemolekyuli, ngaloo ndlela kwandisa i-viscosity. Ngokomzekelo, kwi-adhesives yokwakha, ukudibanisa kwe-HPMC kunokunyanzeliswa ngokudibanisa inani elifanelekileyo le-boric acid okanye ezinye ii-ion ezininzi zokufumana inkqubo ye-adhesive high-viscosity.
9. Ulawulo lobushushu kunye nokufuma
Kwizicelo ezisebenzayo, i-viscosity ye-adhesives ye-HPMC ikwachatshazelwa bubushushu be-ambient kunye nokufuma. Ukunyuka kwamaqondo obushushu ngokubanzi kunciphisa i-viscosity ye-HPMC, ngelixa ukunyuka kokufuma kunokubangela ukuguquguquka kwe-viscosity kwi-adhesive. Ke ngoko, ukugcina ubushushu obufanelekileyo kunye neemeko zokufuma kwindawo yokwakha kunokunceda ukugcina i-viscosity efanelekileyo ye-adhesive HPMC.
10. Ukuphucula iimeko zokugcina
Iimeko zokugcinwa kwee-adhesives ze-HPMC zineempembelelo zexesha elide kwi-viscosity. Ukuze kugcinwe ukuzinza kwe-viscosity, i-adhesives kufuneka igcinwe kwindawo eyomileyo, epholileyo, ukuphepha ukushisa okuphezulu kunye neemeko eziphezulu zomswakama. Ukongezelela, ixesha elide lokugcina lingakhokelela ekunciphiseni kwe-viscosity. Ngoko ke, ukujonga rhoqo i-viscosity ye-adhesive kunye nokwenza izilungiso njengoko kuyimfuneko nazo ziyimilinganiselo ebalulekileyo yokuqinisekisa umgangatho wokubambelela.
Ixesha lokuposa: Sep-03-2024