Umahluko phakathi kwe-EHEC kunye ne-HPMC

I-EHEC kunye ne-HPMC ziintlobo ezimbini ezisetyenziswa ngokuqhelekileyo zeepholima ezinezakhiwo zeekhemikhali ezahlukeneyo kunye neempawu. I-EHEC imele i-ethyl hydroxyethyl cellulose, ngelixa i-HPMC imele i-hydroxypropyl methylcellulose. Kweli nqaku, siza kuxubusha umahluko phakathi kwe-EHEC kunye ne-HPMC ngokubhekiselele kulwakhiwo lweekhemikhali, iipropati, ukusetyenziswa kunye nokhuseleko.

1. Ulwakhiwo lweMichiza

I-EHEC i-polymer e-soluble yamanzi ephuma kwi-cellulose. Yi-ether ye-cellulose ehlaziyiweyo enamaqela e-ethyl kunye ne-hydroxyethyl eqhotyoshelwe kwi-cellulose backbone. Iqondo lokutshintshwa (DS) lwe-EHEC libhekiselele kwinani le-ethyl kunye namaqela e-hydroxyethyl akhoyo ngeyunithi ye-anhydroglucose (AGU) ye-cellulose backbone. I-DS ye-EHEC inokusuka kwi-0.2 ukuya kwi-2.5, kunye namaxabiso aphezulu e-DS abonisa iqondo eliphezulu lokutshintshwa.

HPMC, kwelinye icala, ikwayipolymer enyibilikayo emanzini ephuma kwiselulosi. Yi-ether ye-cellulose elungisiweyo ene-hydroxypropyl kunye namaqela e-methyl aqhotyoshelwe kwi-cellulose backbone. Iqondo lokutshintshwa kwe-HPMC libhekiselele kwinani le-hydroxypropyl kunye namaqela e-methyl akhoyo nge-AGU yomqolo we-cellulose. I-DS ye-HPMC inokuqala ukusuka kwi-0.1 ukuya kwi-3.0, kunye namaxabiso aphezulu e-DS abonisa iqondo eliphezulu lokutshintshwa.

2. Iipropati

I-EHEC kunye ne-HPMC zineempawu ezahlukeneyo ezenza ukuba zilungele izicelo ezahlukeneyo. Ezinye zeempawu eziphambili ze-EHEC kunye ne-HPMC zidweliswe ngezantsi:

a. Ukunyibilika: I-EHEC ayinyibiliki kancinci emanzini kune-HPMC, kwaye ukunyibilika kwayo kuncipha njengoko inqanaba lokutshintsha linyuka. HPMC, kwelinye icala, inyibilika kakhulu emanzini.

b. I-Rheology: I-EHEC yimathiriyeli ye-pseudoplastic, ethetha ukuba ibonisa ukuziphatha kokucheba. Oku kuthetha ukuba i-viscosity ye-EHEC iyancipha njengoko izinga lokucheba linyuka. I-HPMC, kwelinye icala, i-Newtonian material, ethetha ukuba i-viscosity yayo ihlala ihleli kungakhathaliseki ukuba isantya sokucheba.

c. Iimpawu zokwenza ifilimu: I-EHEC ineempawu ezintle zokwenza ifilimu, ezenza ukuba zilungele ukusetyenziswa kwiingubo kunye neefilimu. I-HPMC ikwanazo neepropati zokwenza ifilimu, kodwa iifilimu zinokuba brittle kwaye zithande ukuqhekeka.

d. Ukuzinza: I-EHEC izinzile phezu koluhlu olubanzi lwe-pH kunye neemeko zokushisa. I-HPMC nayo izinzile kuluhlu olubanzi lwe-pH, kodwa ukuzinza kwayo kunokuchatshazelwa ngamaqondo obushushu aphezulu.

3. Usebenzisa

I-EHEC kunye ne-HPMC zisetyenziswa kuluhlu olubanzi lwezicelo kumashishini okutya, amayeza, kunye nokhathalelo lomntu. Ezinye zezinto eziphambili zokusetyenziswa kwe-EHEC kunye ne-HPMC zidweliswe ngezantsi:

a. Ishishini lokutya: I-EHEC iqhele ukusetyenziswa njenge-thickener, stabilizer, kunye ne-emulsifier kwiimveliso zokutya ezifana neesosi, izinxibo, kunye nempahla ebhakiweyo. I-HPMC ikwasetyenziswa njenge-thickener kunye nokuzinzisa kwiimveliso zokutya, kodwa isetyenziswa kakhulu njenge-agent yokugquma kwiimveliso zeconfectionery ezifana ne-gummy candies kunye neetshokolethi.

b. Umzi-mveliso wamachiza: I-EHEC isetyenziswa njenge-binder, i-disintegrant, kunye ne-agent yokugqoka i-tablet ekuqulunqweni kwamayeza. I-HPMC ikwasetyenziswa njengesibophelelo, i-disintegrant, kunye ne-ejenti yokugquma ithebhulethi kwimixube yoxubo, kodwa isetyenziswa kakhulu njenge-arhente yokukhutshwa okuzinzileyo.

4. Ukhuseleko

I-EHEC kunye ne-HPMC zithathwa njengekhuselekile ukusetyenziswa kwizicelo zokutya kunye nezamayeza. Nangona kunjalo, njengakuyo nayiphi na into yeekhemikhali, kusenokubakho imingcipheko ethile eyayanyaniswa nokusetyenziswa kwazo.