I-Hypromellose, eyaziwa ngokuba yi-hydroxypropyl methylcellulose (HPMC), isithako esisetyenziswa ngokubanzi kwiindidi zamayeza, kubandakanywa izongezo zokutya. Yipolymer eyenziweyo evela kwi-cellulose kwaye isetyenziswa ngokuqhelekileyo njenge-thickener, stabilizer kunye ne-emulsifier kumashishini okutya kunye namayeza. Njengayo nayiphi na into, ukhuseleko lwe-hypromellose kwizongezelelo luxhomekeke kwizinto ezahlukeneyo, kubandakanya idosi, ukucoceka, kunye nempilo yomntu.
1. Isishwankathelo se-hypromellose:
IHypromellose yipolymer eyisemi-synthetic eyeye-cellulose ether yosapho. Ithathwe kwi-cellulose yezityalo kwaye isetyenziswa ngokubanzi kumashishini amayeza kunye nokutya ngenxa yeempawu zayo ezininzi. Kwizongezelelo, i-hypromellose idla ngokusetyenziswa njengempahla ye-capsule ukunceda ukwenza igobolondo efana ne-gelatin efaka izithako ezisebenzayo.
2. Iinjongo zonyango:
I-Hypromellose inembali ende yokusetyenziswa kwishishini loxubo mayeza kwaye yaziwa ngokubanzi njengekhuselekile (GRAS) zii-arhente ezilawulayo. Isetyenziswa rhoqo njenge-excipient ye-pharmaceutical formulations ngomlomo, kubandakanywa iipilisi kunye neepilisi. Ubume be-inert ye-hypromellose yenza kube yinto efanelekileyo yokukhetha ukuhambisa izithako ezisebenzayo ngendlela elawulwayo kunye nokuqikelelwa kwangaphambili.
3. Ukhuseleko lwezongezo:
A. I-Digestibility: I-Hypromellose ithathwa njengento yokwetyisa kakhulu. Idlula kwinkqubo yokugaya ngaphandle kokufunxwa egazini kwaye ekugqibeleni ikhutshwe emzimbeni. Le propati yenza ukuba ibe yimpahla efanelekileyo yokudibanisa iintlobo ezahlukeneyo zezongezelelo.
b. Ukuvunywa kwe-Arhente yoLawulo: I-Hypromellose ivunyiwe yi-arhente ezilawulayo ezibandakanya i-US Food and Drug Administration (FDA) kunye ne-European Medicines Agency (EMA) yokusetyenziswa kweziyobisi kunye nokutya. Ukuvunywa okusemthethweni kunika inqanaba lengqinisekiso yokuba ikhuselekile xa isetyenziselwa izongezo.
C. Hypoallergenic: I-Hypromellose ngokuqhelekileyo i-hypoallergenic kwaye inyamezeleke kakuhle ngabantu abaninzi. Ngokungafaniyo nezinye izixhobo ze-capsule, njenge-gelatin, i-hypromellose ayinazo izithako zemvelaphi yezilwanyana, iyenza ifanele abantu abatya imifuno kunye nabantu abanezithintelo ezithile zokutya.
4. Iinkxalabo ezinokwenzeka:
A. Izongezo kunye nezihluzi: Ezinye izongezelelo zingaqulatha ezinye izongezo okanye izihluzi kunye ne-hypromellose. Kubalulekile ukuba abathengi baqonde uluhlu olupheleleyo lwesithako kunye nomthombo we-hypromellose ukuqinisekisa umgangatho opheleleyo kunye nokhuseleko lokuncedisa.
b. Iimvakalelo Zomntu Ngamnye: Nangona kunqabile, abanye abantu banokufumana ukungonwabi kwesisu okanye ukuchasana ne-hypromellose. Kubantu abanolwazi olwaziwayo okanye abakwaliwayo, kuyacetyiswa ukuba udibane nengcali yezempilo ngaphambi kokusebenzisa izongezo ezine-hypromellose.
5. Imilinganiselo yomthamo:
Ukukhuseleka kwayo nayiphi na into, kubandakanywa ne-hypromellose, ngokubanzi kuxhomekeke kwithamo. Kwizongezelelo, ukuxinwa kwe-hypromellose kuyahluka ukusuka kwifomula ukuya kwifomula. Kubalulekile ukuba umntu ngamnye alandele imiyalelo yedosi ecetyiswayo enikezwe ngumenzi wezongezo okanye ingcali yezempilo.
6. Isiphelo:
I-Hypromellose ngokuqhelekileyo ithathwa njengekhuselekile xa isetyenziswa njengesongezelelo kwiidosi ezicetyiswayo. Ukusetyenziswa kwayo ngokubanzi kumayeza kunye nokuvunywa kwayo ngamaqumrhu alawulayo kubonisa ukhuseleko lwayo. Nangona kunjalo, njengaso nasiphi na isongezelelo okanye isithako samayeza, abantu kufuneka balumke, baqonde uluhlu olupheleleyo lwesithako, kwaye badibane nochwepheshe bezempilo ukuba banenkxalabo okanye iimeko zempilo esele zikho.
IHypromellose sisithako esamkelwe ngokubanzi kwaye sikhuselekile kwizongezelelo xa isetyenziswa ngokufanelekileyo. Njengaso nasiphi na isigqibo esinxulumene nempilo, abantu kufuneka baxelele abathengi, bafunde iilebhile zeemveliso, kwaye badibane nochwepheshe bezempilo xa kuyimfuneko ukuqinisekisa ukusetyenziswa okukhuselekileyo nokusebenzayo kwezongezo ezine-hypromellose.
Ixesha lokuposa: Dec-21-2023